Recent content by dietcoke1987

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    Is Microneedling Best With Topical minoxidil? Or Can I Still Get Good Results If I Needle + Oral Min?

    How do you supplement sulfurotransferase? Was that a typo "supplementing" sulfurotransferase? Do you mean supplement to increase it? If so what does a person supplement?
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    Botanically Derived, Β-cyclodextrin Inclusion Complex Study

    So would a person just add beta-cyclodextrin powder to any water based liquid at 2.16% and use a magnetic stir for a long time or sonicator to mix it in and that gives you a cyclodextrin enhanced delivery product? Am I understanding this right? It wouldn't be as optimized as possible but I...
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    Using A Sonicator Or Mechanical Homogenizer To Mix Solutions

    Seems helpful but the thing to keep in mind here is it's a balancing act so to speak. You want it to penetrate but you don't want it so much so that it's almost completely mobilized and doesn't stay localized. We aren't trying to administer a drug to go systematic and be wasted. We want it to...
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    Using A Sonicator Or Mechanical Homogenizer To Mix Solutions

    Is there a reason why you choose that over magnesium threonate form or iccarin which is easy to find in very high concentrations 40%+ from horny goat weed extracts for DKK-1? Film forming cosmetic additives/actives such as for tightening and certain hydration formulations and also gelling agents...
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    Yo What Happned To The Private Forum? They Disappeared?

    lmao what? The mods were on a powertrip and insane on there and drove many away.
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    Topical Dutasteride And Microneedling Study

    Who said I haven't already? I wasn't exactly ever fishing for your approval lol, just pointing out penetration clearly isn't an issue like you believe. Even assuming minimal efforts are used for limited penetration, it's tendency to stay localized with extremely long half life will give...
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    Topical Dutasteride And Microneedling Study

    Exactly, like I said there are a multitude of ways to bypass the 450/500 dalton rule of thumb and many more since two decades ago. There obviously has been a lot of research into liposomes in the last two decades since your cited paper far less in the cosmetic industry alone...
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    Topical Dutasteride And Microneedling Study

    I really don't care. It's a pretty irrelevant concern from my perspective. There are many ways to bypass it by way of carrier formulation or application or skin prep. Also beyond all of that none is needed by way of the follicle channel which I already brought up. Lactoferrin is something like...
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    Topical Dutasteride And Microneedling Study

    I think the point is Dutasteride is supposed to be more hydrophobic and lipophilic than finesteride which means it will want to stay put in the local area of application in the skin than go into the blood stream and go systematic. I don't know why this isn't being brought up that's the most...
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    Sodium Thiosulfate: A Way To Reset Scalp Calcification?

    No, EDTA+Omega3 is meant to be taken daily for life for all of it's cardio benefits. EDTA for long term use requires a good form multi mineral to be taken daily. It will actually enhance the utilization of the minerals too. Albion multi mineral is a good, solo stand alone multi mineral that's...
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    Sodium Thiosulfate: A Way To Reset Scalp Calcification?

    calcium disodium edta 600-800mg orally daily with a albion multi mineral will be far more effective and safer for removing calcification. According to experts for total body removal of calcification in soft tissue with that dosage of EDTA it takes about 9 months. I've been on it for 8 years and...
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    Lactoferrin As A Promoter Of Hair Growth

    That formulation was irrelevant to the study. It was mentioned only to note for future application that lacoferrin can be stabilized and put in topical form with a reasonable shelf life. They used 300mg/ml lactoferrin in the study.
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    Update Giving What Jak Pathway Needs To Be Inhibited

    No I haven't, just trying to get the discussion going so people can brainstorm.
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    Update Giving What Jak Pathway Needs To Be Inhibited

    It is around 15 USD for 28 pills of 100mg on alldaychemist. They ship international. That was also just a suggestion of one possible option. I was hoping there would be discussion of other substances now that we know specifically what to target.
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    Stimulation Of Hair Growth By Small Molecules That Activate Autophagy

    It's something that could easily be added to the lactoferrin topical. Any idea the mg per ml? Would it be around 0.5mg per ml?
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