Recent content by Dimitri001

Can anyone else confirm, please? Because it STILL doesn't work for me, whatever browser I try it on. I tried on my laptop, my desktop and doesn't work on neither.

Thank you.

https://libstc.cc/ is, I understand, the most up to date free database of scientific literature, but it's not worked for me for a few days now. Does it work for you? Could you try downloading any random paper and tell me if it works? I always get a "504 Gateway Time-out" message when I try to...

https://link.springer.com/article/10.1007/s00266-024-04439-7

Whenever I read this, my main question is, so what's the cancer potential? This is kind of interesting: Wait, am I reading this correctly? They just shaved the mice, they didn't even apply DHT? Well, that's a pretty lousy model for Androgenetic Alopecia.

One thing he says that I thought was particularly interesting is that it is very difficult to obtain human hair follicles to use as models and that this is the main thing that governs the rate of progress in Androgenetic Alopecia research. That if you could make follicles more easily obtainable, speed of research...

https://pubmed.ncbi.nlm.nih.gov/39215942/ Could this point to some unknown mechanism? I don't remember these enzymes ever being mentioned in Androgenetic Alopecia pathophysiology (if mutant enzymes are even something people without gliomas have). Unless the drug also has other effects that may somehow influence...

It beat 5% minoxidil, sounds pretty good.

At a commercial lab, how else.

I'm interested in measuring my DHT levels to look at how a certain intervention will affect them, but I don't know how variable they are day to day, week to week. Do they vary a lot naturally? Is a single measurement before and a single after sufficient to detect a change or does the level vary...

Around the time my hairloss first started, I would see a lot of miniaturized hair all the time and then there was a period of a few years where there was no miniaturization, at least not in the front where I would normally observe it. IDK whether this is typical, but judging by this it seemed as...

Something that will fail in phase 2.

So, given that the drug doesn't bind to the receptor, but can, after interacting with it, go on to tag other receptors for deletion, as Kevin says in the video, how is this drug metabolized and cleared?

On the topic of the cost of antibodies. A bit I came across in a study on H. pylori immunotherapy:

So there is this suspicion that creatine may contribute to hair loss due to one study that found an increase in DHT levels in subjects given creatine. I've heard this notion poo pooed on the basis that the study has never been replicated, but has anyone ever tried replicating it? Are there any...