Recent content by edh38

please do my man!

Growth stimulant It's a bit more complicated imo and I don't wanna forecast results for thyroid hair loss. I also got diagnosed with subclinical hyperthyroidism (and have diffuse thinning only) and have hopes for this indication too.

Yes, there is no connection between them. Group buy is still active for 2 more days.

For anyone wondering about this thread and the other one with a similar name: look at the creation date, this was first and Pegasus just stole the name.. The GB is currently ongoing, if you would like to join, DM me.

didnt they already finish a trial where they dosed women? I guess hair growth was not experienced there but that's where the different..hf physiologies come into play?

Last call guys if you wanna get in and have a good shot at actually regrowing hair dm me

I understand, but at the same time - do you realize that Minoxidil upregulates Shh (this, again should have been more than clear if you would have read the Yale paper e.g.)? It's not just about 'how much', but also about 'how'. Seems like you are making a case of direct hyperactivation of Shh...

Yup, we don't. It's called scientific conclusion. And yeah Shh is very dangerous, which makes the initial safety pass just more impressive.

i've looked for it but couldnt find it. however the author is now a prof at the uni of san francisco: https://lijiejackli.wixsite.com/usflab/jjl

androgenetic alopecia, male pattern baldness.

TDM-105795 is a topical Thyroid-Receptor beta-1 agonist currently in clinical trial for hair growth. It is developed by Technoderma, a Chinese company founded by ex-Pfizer employees. Previous research on such a substance has been, among others, conducted by Pfizer and Ralf Paus' Monasterium Lab...

nice, will take a closer look at the paper later. There's also a paper saying that, surprisingly, PCLAF was found to be very correlated with anagen promotion / wnt/shh activation simultaneously.

he's already organising another gb rn addressing wnt+ssh in a safe way, tdm. About halfway thru minimum order quantity, need 17 more people: https://discord.gg/GwgdRVgx And about the topic: There's the explicit statement that WNT is necessary but not sufficient for anagen promotion in a major...

Or the goal is to get the most bang for your buck..semantics not worth talking about, much less as an argument. Just fyi- a 1b following a 1a is the norm. The 1a consisted of groups which received tdm once, whereby the tdm concentration per group varied. called Single-Ascending-Dose (SAD)...

this is more than standard - phase 1 costs are approx. 1/10 of phase 2+ phase 3 costs so if you can go higher from a safety pov and prior research suggests it is beneficial, you would do it..