Recent content by hemingway_the_mercenary

not sure about difool but I think they were using 0.1% concentration which I said from the beginning had no chance of working. I think they needed at least 1% to stand a chance and no one could afford that

In my own opinion, the doses they were using we way too low. They were treating this drug as if it's as potent as finasteride when its clearly not. This is partially the problem wtih doing group buys for drugs, sometimes the raw powder is so expensive. you cannot afford to use it in the...

I’ve edited the invite link once more. Should be valid again, check the op.

You have no idea what you are talking about. The finasteride trials and not designed to actually find occurrence of sexual sides. If they were you'd see them measure how quickly it takes to achieve maximal erection with normal stimuli and how long the male is able to maintain erection without...

Topical Min with retinol is only about 10% better than just topical min alone at best, that’s why I meant

the downsides of oral minoxidil are much deeper than just body hair growth. It is 10x more effective than topical minoxidil with retinol. That is only like 10-15% better at best than min without retinol

If topicals could actually be absorbed in sufficient dosages topical anti androgens would be the cure. The real barrier is absorption not going systemic. Super potent drugs like finasteride, dutasteride, or even estradiol can be absorbed in more than sufficient dosages but when you need ~5mg of drug to be...

What kind of clown are you? If you have nothing helpful to add why are you interfering?

@John Difool have you considered using a mesotherapy gun to inject the ARV-100 into the scalp? This could be done maybe 1x per week and would be able to deliver much more of the drug than any other means of application. The only issues are creating a sterile injectable solution that is not...

I’ll edit an updated version in there

You weren’t even in on the Darolutanide group buys from what I remember were you? Why are you saying “we”? If you were you’d know that no one got sexual sides from it, the only downside was that it didn’t stop miniaturization like we’d hoped, wasn’t potent enough. For everyone else, im not...

long serum half life won't even matter for the very low amount of absorption that occurs from the scalp (unfortunately otherwise male pattern baldness would be so easy to cure). Look at minoxidil for example, quite a long half life and causes strong systemic side effects when taken orally at ~5mg even yet applied...

https://clinicaltrials.gov/ct2/show/NCT04502901

I looked at the phase I published results and the highest dose they used was 20mg from what I found. If true that’s actually quite promising as cb was used at 7.5% or 75mg per ml in their studies. Usually in phase 1 studes they give a dose way higher than needed to be effective to test safety...

We can just source the powder if it’s actually effective which I doubt tbh