Recent content by ngc800

I have had PFS for 3 years now. Some people have had it for 20. The subjects in Melcangi's sample have had it for years. What is your definition of not permanent? How do I remove the methyl groups?!

Link? How about this? https://www.ncbi.nlm.nih.gov/pubmed/31272082

What kind of homeostasis is that? My proper gene expression homeostasis that's been epigenetically altered by Finasteride?

Do you know anyone who has benefited from these? What's your story? I am currently taking transdermal DHT, as I have permanently reduced DHT levels, so that's equivalent to Proviron. It doesn't do much for core PFS symptoms, although it improves my joint pain a lot. I haven't tried TRT yet but...

Penis tissue and all tissue of the reproductive tract - prostate, seminal vehicles, testes, etc - are androgen dependent. They need androgens -- of which DHT is the more potent one -- for tissue maintenance, not just in development. Androgen deprivation leads to apoptosis - cell death. This of...

So I was asked in private when I developed PFS - while I was taking finasteride or after I stopped. I will answer but before that a warning: Do not let this anecdotal evidence and fear mongering get to you! Please continue to take finasteride as prescribed. The more people there are with PFS...

As someone who has a very serious case of PFS with life-altering and life-threatening symptoms that I fight every minute of every day, my position on this debate is the following: Let the deniers take Finasteride.

In terms of the volume of a pea, how many pea volumes do you use?

In terms of pea sizes, how many do you think one pump of the cream is equivalent to? I am trying to estimate your total dose of DHT. An alternative way to ask the same question is, how long do you think one bottle of the cream will last you? The bottle is 100ml so, for example, if it lasts for...

So you consider yourself recovered from PFS while you are on the DHT treatment? Can I ask how much of the 2.5% formulation you use daily? Have you measured your DHT since you started the treatment? I also have PFS and below normal DHT and also take transdermal DHT but I have no results on core...

Hi vailj9, I am so sorry to hear. He should make an account on PropeciaHelp. That's the best way to get support and understanding around the condition. Unfortunately there are no treatments available currently. Some people who are not affected severely improve over time.

Is the risk of having your whole life totally destroyed a serious risk? I don't know...

Finasteride has a very flat dose-response curve, meaning that you need to lower the dose a lot to see a reduction in its action. That's why I said that effective tapering implies going to doses as low as 1/16th and 1/32th of standard dose. One-half of a dose wouldn't make such a big of a...

If you decide to stop I recommend doing it very, very slowly to avoid jolting the system. Taper off over a two year period and go to a very low dose at the end, like 1/32th. You are likely going to lose a substantial amount of hair - more hair than you would have lost over these 20 years had you...