Recent content by tgfbeta

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    The Cb (breezula [clascoterone]) Community Thread

    You're not wrong, but I'm just sharing my personal experience with the supposed drug. This is all contingent on me having used the legit chemical, which is why I haven't attempted to claim that CB is dangerous. However, I do trust my current urologist who is treating me. Independent of what...
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    The Cb (breezula [clascoterone]) Community Thread

    Not so good. Long story short, I developed penile fibrosis which was found with an ultrasound test. I'm currently taking cialis daily and undergoing weekly shockwave therapy to help break up the fibrotic tissue that's causing erectile dysfunction. All of my symptoms are in line with pfs, except...
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    The Cb (breezula [clascoterone]) Community Thread

    This provides grounds for further independent research - using antibodies for AR and measuring them in DP over time.
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    The Cb (breezula [clascoterone]) Community Thread

    If anybody is familar with the cortisol synthesis pathway please let me know. I have not studied it enough to make any connections yet; however, I've come across a possible culprit: 17 alpha-hydroxylase/17,20-lyase deficiency. It could be possible that the HPTA suppression caused by excessive...
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    The Cb (breezula [clascoterone]) Community Thread

    My personal theory, like others have said above, is HPTA suppresion causing strong negative feedback on the hormone profile, which can theoretically explain hair loss. Honestly, from what I've read so far regarding upregulation of AR, AA can downregulate AR expression; conversely, it's been...
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    The Cb (breezula [clascoterone]) Community Thread

    It's not nocebo, I promise you. 0%
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    The Cb (breezula [clascoterone]) Community Thread

    Yes. I wrote it in the midst of frantic mood today. I still cannot believe it's really happened to me. Pigeon, have you had pfs-like symptoms before?
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    The Cb (breezula [clascoterone]) Community Thread

    Update: My total testosterone came in today. Pre-treatment I had 650 total T. Today it's 540 total. Waiting for my estradiol results to come in too. My LH and FSH are not far off from baseline, so those are okay.
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    The Cb (breezula [clascoterone]) Community Thread

    Thank you for the words of encouragement. I took it for 2 weeks. I've never taken anything else. I microneedle but stopped during CB to avoid any systemic sides. Didn't matter in the end. I'm back to needling but I'm seeking treatment from multiple urologists right now to undo the effects. All...
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    The Cb (breezula [clascoterone]) Community Thread

    Only time will tell. Once I have it tested we'll know the verdict on CB. At this point I just want a path towards recovery. I could care less about my hair anymore. Health truly is most important.
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    The Cb (breezula [clascoterone]) Community Thread

    50 mg/day. Yeah HPTA axis shutdown could be my problem. Dropped LH and FSH -> underactive testes -> reduced T. Honestly I have most of the sexual sides people have on propeciahelp. Things have gotten progressively worse since I've stopped too.
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    The Cb (breezula [clascoterone]) Community Thread

    Thank you. While I'm waiting for my labs, I spoke to another urologist who believes that CB increased testosterone levels significantly, leading to high aromatization into estrogen, which subsequently caused anti-androgenic effects, suppressing my FSH and LH. In addition, he believes that I may...
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    The Cb (breezula [clascoterone]) Community Thread

    Could HPTA axis shut down cause sexual side effects? I cannot find references that correlate the two.
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    The Cb (breezula [clascoterone]) Community Thread

    Yes. It's crazy. I'm still in shock honestly. I'm trying to stay positive but it's really hard emotionally. It makes you realize how much more important sexual health is than hair. I've ordered blood work which I'll post publicly once the results come in. It will show my FSH, LH, T, DHT, E2...
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