A new gene identified in some alopecias............

michael barry

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Gene defect linked to baldness

By Kerry Young, Bloomberg News | November 10, 2006

WASHINGTON -- Scientists have identified a genetic defect in some people who have trouble growing hair, opening a new avenue for research on treatments for baldness, according to a study in today's edition of the journal Science.

An enzyme called lipase H may help hair grow and develop, researchers wrote. A specific gene, LIPH, which allows the body to produce the enzyme, is defective in some members of Russia's Chuvash and Mari populations, in which even young girls sometimes inherit a form of baldness, the scientists found.

About one in four men begins to lose hair by age 30, and two in three will be bald or "have a balding pattern" by 60, according to the US National Institutes of Health.

Although drugs such as <ORG idsrc="NYSE" value="PFE">Pfizer</ORG> Inc.'s Rogaine are sold to treat hair loss, the medicines don't work for everyone, and the response to the products can't be predicted.

The new research "identifies a novel molecular pathway in regulation of hair growth," said Evgeny Rogaev, the leader of the study and a geneticist at University of Massachusetts Medical School in Worcester, in a Nov. 7 e-mail. "Experiments in animals will be required to prove these predictions."



I hope couteracting this gene can help these people. It may not help men with androgenic hairloss, but then it again it might. Its sad to see a young woman lose her hair though. Hope they can help em' out.
 

person_123

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let's hope they make a cure based on this soon.

that way, we can pop one pill. alter our genes (hopefully no side effects), and be done with balding.
 

Apoc

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It will be 15 years minimum before such a thing comes to the market.
 

docj077

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This gene may be defective in some women, but they must inherit a normal copy, as well, because it impacts way too many tissues. You can't shut this gene off and if it isn't defective, then there is no reason to even be concerned with it.

Its true designation is a Membrane-bound phosphatidic acid-selective phospholipase A1

http://www.genecards.org/cgi-bin/carddi ... earch=LipH
 
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