General thoughts on RU58841

SniperWolfMR

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Where to begin...

Back in November my finasteride decided to stop working, Yes, literally stopped. All of the hair on top of my head began to miniatuize. Hair CAN miniaturize without shedding and regrowing, I saw it first hand.
The shedding was unbelievable as well. The difference in my hair in the matter of 4 months (after great success) was mind boggling.

I decided to start RU after seeing the few (very few) documented accounts of success. When I first started RU, I was using around 130-140MG every application. This dose gave me noticeable chest pains. By chest pains I mean an actual pain in my heart. Upon lowering my dosage to around 80mg, the chest pains immediately went away. It has been said many times that you need to find your dose when it comes to RU and this is true.

Do I believe RU decreased my shedding? I honestly think it may have. Not to the point of where I was when I was in the prime of my finasteride usage. At this very point, I have been on RU for 110 days.

RU58841 has made no, and I mean ZERO improvement In the diameter, density or appearance of a single strand of hair. This is concerning because I know of many users of this forum that think RU58841 alone will give them results, which I think is just close to impossible. I am on finasteride and RU and I feel like these last 4 months I have actually lost density in my hairline. I am aware of hellouser and irishpride (who must now be in the witness protection program) used RU alone and had astonishing results. Honestly, it just doesn't make any sense at all and I think if these accounts were not online and so drastic, this Kane guy would not be in business. I also know Swoop is a heavy advocate of RU but no offense to Swoop, he had a fairly large transplant so how he actually knows RU is working is questionable.

I sometimes convince myself "oh this is just the weaker hairs shedding, these things take time". Upon inspecting my hair under harsh light every few weeks I come crashing back to reality.

I just want everyone to know that RU58841 is not what these few success stories make you believe, It's not even a fraction of that. I think this Kane guy has taken enough of everyones money and it may be time to actually write off RU as an effective treatment.
 

whatevr

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Well, I am one of those people for whom Finasteride doesn't work. Am I supposed to assume it doesn't work for anyone? I'd still tell people to try it.

I have no personal experience with RU. However, given that it's an abandoned illegal research chemical, considering the number of people trying it, do you suppose to hear success stories on RU every day by the dozens?
There is no guarantee it'll work. You don't even get that with Finasteride which is something you can buy in your pharmacy with tons of studies backing it.
Given the situation, if it works even for one person it's good because that one person otherwise wouldn't have an option. We don't really have shelves lined up with hair loss treatments just ready to pick one out.

So whatever. It sucks that it didn't work for you but why do you want to discourage others from trying it?
 

SniperWolfMR

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Well, I am one of those people for whom Finasteride doesn't work. Am I supposed to assume it doesn't work for anyone? I'd still tell people to try it.

I have no personal experience with RU. However, given that it's an abandoned illegal research chemical, considering the number of people trying it, do you suppose to hear success stories on RU every day by the dozens?
There is no guarantee it'll work. You don't even get that with Finasteride which is something you can buy in your pharmacy with tons of studies backing it.
Given the situation, if it works even for one person it's good because that one person otherwise wouldn't have an option. We don't really have shelves lined up with hair loss treatments just ready to pick one out.

So whatever. It sucks that it didn't work for you but why do you want to discourage others from trying it?

Everything about RU is just not right to begin with. We have guys who are trying to make an income off their bodybuilding blogs promoting it on YouTube, it's cost, it's unknown purity etc. Yes, everyone knows it's a research chemical going in and if it was producing half the results that these select few people claim then I would be an advocate, but it just doesn't. I know many people will soon back me up on this. ru58841 is just not worth it, plain and simple.
 

whatevr

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Everything about RU is just not right to begin with. We have guys who are trying to make an income off their bodybuilding blogs promoting it on YouTube, it's cost, it's unknown purity etc. Yes, everyone knows it's a research chemical going in and if it was producing half the results that these select few people claim then I would be an advocate, but it just doesn't. I know many people will soon back me up on this. ru58841 is just not worth it, plain and simple.

The fact that there is no SAFE, LEGAL, EFFECTIVE alternative for RU (and current year yadda yadda there damn well should be) tells you everything you need to know. RU is primarily used by people for whom Finasteride doesn't work alone, or instead of Finasteride and those people are desperate. We should've had something like CB ages ago. RU is overpriced, potentially unsafe and a pain in the *** to deal with but it saves some people's hair. I just doubt everyone who ever posted a success story is a Kane shill, although it's DAMN suspicious that he seems to be the only one selling it.
 

SniperWolfMR

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What probably happened was him and his chemists took their time making batches in 2012-2013. People started seeing success and the money came in. Once this happened im sure they dropped the ball and started cutting corners and got lazy. It's sort of a genius idea. No one can prove it's working until they buy at least 6 months worth, they take advantage of the placebo effect and for all the nay sayers, people point to these few accounts of success. Testing purity is insanely expensive so what Kane has now is a bunch of balding zombies just throwing money at him
I wish I thought of this.
 

Swoop

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Well I'm not necessarily a very big advocate of RU. I think it's a tier 1 treatment together with finasteride etc. It has a different mode of action, and when people can't handle finasteride (due to side effects) or people can't maintain on a 5ar2 inhibitor because they bald very aggressively they have a possible way out and that is switching to a anti-androgen like RU or adding it to their regimen. Still first line of action should be finasteride.

The problem is that people love to stare down on the best results. Problem is, very little people get actually such awesome results like Irishpride or hellouser. You can be considered extremely lucky if you get such results like them.

I mean if you don't improve on finasteride + RU58841 then I have bad news for you man. Castration isn't probably even going to cut it for you. Your only line of action is either going full eunuch by adding estradiol and slashing down your T (no man should do that obviously). Or you can take a second route of action and that is using a "kitchen sink" regimen by dumping various things into your regimen. Very often the latter is simply not worth it by the amount of effort you got to put in for the minimal results (also health and practical wise imo). Better option at that point is a hair transplant imo, which you could look into (if you maintain).

I can understand the frustration but this is Androgenetic Alopecia bro. Approximately 5-8% of minoxidil users get very good cosmetic improvement if I remember correctly from studies as evaluated from photographs. They are the lucky ones, but not everyone can be so lucky.
 

Coiffio

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Both treatments ultimately work because less androgens are attaching to your follicles. If nuking your DHT stopped working, I wouldn't be that optimistic about another treatment that prevents some of the androgens from attaching to your follicles.

I've had a ton of success with daily RU + .25mg of finasteride twice a week. RU is still the only thing that keeps my hair grease free. I don't like thinking about the day these treatments stop working.
 

buckthorn

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RU may f*ck you, finasteride may f*ck you. RU may help you, finasteride may help you. I have learned first hand the devastating effects finasteride can have if your body counteracts it. I don't CARE if finasteride is FDA approved and has studies backing it. It's a multi million dollar industry and people have horrible effects or die from prescription medications every day. Every physiology is different. You try finasteride, it doesn't work, let it go. You try RU, monitor yourself carefully and if it doesn't work let it go. This is just how this game works. It sucks, but it's a reality. I am 4.5 months on RU now and can't say I notice any difference. At first I shedded a TON, but that may have still been the after effects of finasteride. Now, in the past month, my hair seems to have stabilized (i should NEVER say this, because every time I do, the Androgenetic Alopecia g*ds decide to f*ck me).

There are many questions with RU obviously since there is lacking published research on it's effects with Androgenetic Alopecia. Is the vehicle effectively carrying it into the dermis? Is it permeating the cell and getting to it's target? Once there, is it adequately doing it's job and binding to receptors? ok, good.. but is this causing feedback in the cells to produce more receptors for DHT to bind? blah blah blah... YOU never know unless you try and stay consistent for at least six months. Like Swoop said, if RU doesn't work for me, then it's a few months on both RU and dutasteride... if that doesn't work, hello Hasson and Wong.
 

abcdefg

Senior Member
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Yeah the only reason we are even talking about RU is because short of propecia what else really is there? RU has a long laundry list of potential issues, and problems but it also attacks the AR which is a very important angle. I really wish we had a CB or RU sitting on shelves somewhere because its a very important angle of attack even stronger when combined with propecia since neither one is 100 percent effective.
With current options RU is just the kind of pathetic backup if finasteride doesnt work. Hopefully seti, SM or something can give us alternatives sooner rather then later.
 

Iopu

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I'm finding that RU is working pretty good for me. (In combination with minoxidil).
I've tried finasterade and get too many sides.
 

losingbattle88

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Where to begin...

Back in November my finasteride decided to stop working, Yes, literally stopped. All of the hair on top of my head began to miniatuize. Hair CAN miniaturize without shedding and regrowing, I saw it first hand.
The shedding was unbelievable as well. The difference in my hair in the matter of 4 months (after great success) was mind boggling.

I decided to start RU after seeing the few (very few) documented accounts of success. When I first started RU, I was using around 130-140MG every application. This dose gave me noticeable chest pains. By chest pains I mean an actual pain in my heart. Upon lowering my dosage to around 80mg, the chest pains immediately went away. It has been said many times that you need to find your dose when it comes to RU and this is true.

Do I believe RU decreased my shedding? I honestly think it may have. Not to the point of where I was when I was in the prime of my finasteride usage. At this very point, I have been on RU for 110 days.

RU58841 has made no, and I mean ZERO improvement In the diameter, density or appearance of a single strand of hair. This is concerning because I know of many users of this forum that think RU58841 alone will give them results, which I think is just close to impossible. I am on finasteride and RU and I feel like these last 4 months I have actually lost density in my hairline. I am aware of hellouser and irishpride (who must now be in the witness protection program) used RU alone and had astonishing results. Honestly, it just doesn't make any sense at all and I think if these accounts were not online and so drastic, this Kane guy would not be in business. I also know Swoop is a heavy advocate of RU but no offense to Swoop, he had a fairly large transplant so how he actually knows RU is working is questionable.

I sometimes convince myself "oh this is just the weaker hairs shedding, these things take time". Upon inspecting my hair under harsh light every few weeks I come crashing back to reality.

I just want everyone to know that RU58841 is not what these few success stories make you believe, It's not even a fraction of that. I think this Kane guy has taken enough of everyones money and it may be time to actually write off RU as an effective treatment.






Hello buddy. I had bad experience with RU aswell.. it thinned my hair in spots after 2-3 months and I dont think the hair recovered after that. and I did shed maybe 5-10 more hairs on it. but when I applied the RU on my scalp and rubbed it in then later saw how thin my hair had gotten in 2 places of my scalp I freaked out and quit right away. then the thinning in those spots did NOT continue to thin for years just very slowly. but had thinning fast for 2-3 months on RU and im positive that I didnt imaginate it. my friend who tried it told me it "killed" his hairline when he applied it there. and he ended up getting a hair transplant to fix it. and I read another guy that used RU saying that RU thinned out his hair and turned it into straw.. im just scared to try RU again after my experience. I just cant risk it again. thanks for your post you speak the truth about RU being promoted by some youtubers such as "more plates more dates" and forum members and they get money by promoting it or a discount, also I did get chest pains too on RU it was like a pressure on my chest area and near the adams apple. peace bro.
 
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