Lost my libido using Topical spironolactone...

Beast80

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Hi guys I need some help badly I'm 31 years old, 5 months back I concocted my own blend of spironolactone, mixing about 20 pills of Aldactone with some Aloe Vera Gel. I used it for about 4 weeks when I started realizing that my erections were getting weaker and weaker.

I have stopped using it, but since then I have not recovered. My Libido is almost non existant and if I think of something sexual I cannot get any erections unless I use my hand. Even then, my erections are not as strong as they used to be. I'm very scared because I think I may have effed up my doctrine system.

Please is there something I can use to return my libido and erections back to normal? I am currently taking Zinc and thinking of adding Magnesium. But the reason I'm panicking so much is because my system should go back to normal by itself which it hasn't. Please if someone has gone through this please help me.
 

twenty.five

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I can assure you that your "doctrine system" is fine.

This is all psychological. Topical spironolactone is NOT systemically absorbed. It also has no proper evidence to suggest it works.
 

Primo

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twenty.five said:
I can assure you that your "doctrine system" is fine.

This is all psychological. Topical spironolactone is NOT systemically absorbed. It also has no proper evidence to suggest it works.

Don't listen to that tool... Your sides are definitely NOT "psychological", there's no scientific evidence out there to suggest that topical spironolactone is not systematically absorbed, just like topical Finasteride it will depend on the individual, some are more sensitive than others.

Personally, I got sides of topical spironolactone after 4days and quit and it makes perfect sense given how similar the sides of both oral spironolactone and oral finasteride are to each other. For individuals with a sensitive endocrine system, It only takes the smallest amount to get absorbed into your system and bang!... your hormone balance is f*cked!

Tools on this forum will try to preach the safety of all topical anti-androgens with little or no scientific evidence, but it's best to just use your own common sense, sometimes as some people simply cannot tolerate 5AR inhibitors of any kind.
 

twenty.five

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Primo said:
twenty.five said:
I can assure you that your "doctrine system" is fine.

This is all psychological. Topical spironolactone is NOT systemically absorbed. It also has no proper evidence to suggest it works.

Don't listen to that tool... Your sides are definitely NOT "psychological", there's no scientific evidence out there to suggest that topical spironolactone is not systematically absorbed, just like topical Finasteride it will depend on the individual, some are more sensitive than others.

Personally, I got sides of topical spironolactone after 4days and quit and it makes perfect sense given how similar the sides of both oral spironolactone and oral finasteride are to each other. For individuals with a sensitive endocrine system, It only takes the smallest amount to get absorbed into your system and bang!... your hormone balance is f*cked!

Tools on this forum will try to preach the safety of all topical anti-androgens with little or no scientific evidence, but it's best to just use your own common sense, sometimes as some people simply cannot tolerate 5AR inhibitors of any kind.

Excuse me, sir, I did not preach the safety of it. I think it doesn't work, and all the evidence points to no systemic absorption.

For example:
http://www.ncbi.nlm.nih.gov/pubmed/3411088
http://www.hairlosssucks.com/newsletter ... icle08.htm

I'd love it if you could show any "scientific evidence" that it (a) works or (b) is systemically absorbed to more than a negligible degree.

If you think that a mild topical antiandrogen that isn't systemically absorbed is capable of producing ongoing dysfunction even after application has ceased, well, there's no hope for you.

Good luck with your penis, OP.
 

Shma

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twenty.five said:
Good luck with your penis, OP.

Twenty.five, you're still a "girl" obsessed with Male pattern baldness? :whistle:
 

twenty.five

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Are you just a weirdo in general or do you have reason to believe that I'm someone from these forums under another account?

And no, I am not a "girl". I am an adult, so therefore I am a woman. And I am not "obsessed" with male pattern baldness, I am interested in hair loss as we all are. I happen to have another form of hair loss, but whatever.
 

Primo

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twenty.five said:
Excuse me, sir, I did not preach the safety of it. I think it doesn't work, and all the evidence points to no systemic absorption.

For example:
http://www.ncbi.nlm.nih.gov/pubmed/3411088

What evidence? A study which uses a sample of 6 men??? How much can this really tell us about topical spironolactone's safety profile?

If Merck tested Propecia on 6 random men, the chances are it would also come back "100% safe!!!"

If you can find me a more representative study on topical spironolactone with a substantially bigger sample, I would be very interested, but so far I haven't found one & the one above is pointless.
 

twenty.five

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Primo said:
twenty.five said:
Excuse me, sir, I did not preach the safety of it. I think it doesn't work, and all the evidence points to no systemic absorption.

For example:
http://www.ncbi.nlm.nih.gov/pubmed/3411088

What evidence? A study which uses a sample of 6 men??? How much can this really tell us about topical spironolactone's safety profile?

If Merck tested Propecia on 6 random men, the chances are it would also come back "100% safe!!!"

If you can find me a more representative study on topical spironolactone with a substantially bigger sample, I would be very interested, but so far I haven't found one & the one above is pointless.

It's really funny that you criticise one of my references but cannot provide your own to prove your own point -- that spironolactone is systemically absorbed.

The truth is that there has been barely any research done on topical spironolactone AT ALL, so all we can go by is the little that there is. And the little that there is points to NO systemic absorption.

So once again, feel free to provide me with anything that would cast doubt on that conclusion.
 

Mens Rea

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twenty.five said:
Primo said:
http://www.ncbi.nlm.nih.gov/pubmed/3411088[/url]
http://www.hairlosssucks.com/newsletter ... icle08.htm

I'd love it if you could show any "scientific evidence" that it (a) works or (b) is systemically absorbed to more than a negligible degree.

If you think that a mild topical antiandrogen that isn't systemically absorbed is capable of producing ongoing dysfunction even after application has ceased, well, there's no hope for you.

Good luck with your penis, OP.[/quote:274u1y04]


Excuse me, who do you think you are?

Feel free to take as much interest in male pattern baldness as you like.

But don't try come across as some sort of medical authority.

There would appear to be various reports of systemic absoprtion effects reported across these boards. In fact there has been guys who measured their key sex hormones before and after and found their oestradiol levels to have soared.

The HPTA has various complex feedback mechanisms and when such unnatural and endoctrine disrupting substances are actually absorbed into the blood steam, in certain individuals, the effects can be very pronounced.

Your ignorance is no excuse for your lack of manners - you are outside your realms of knowledge on this one.


TS- if you have ongoing issues its likely you have higher E2. Get it checked. I'd hope you are a far-cry away from the more complex cases that finasteride can bring about. Certainly, id imagine you are.
 

twenty.five

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Mens Rea said:
But don't try come across as some sort of medical authority.

What the hell? I expressed an opinion. You can disagree with me without being an *** about it. My response that you quoted wasn't as polite as it could have been, probably because I was called a tool, but your response to me more than balances it out.

Your anecdotal evidence of stories from these boards aren't that convincing (in my non-medical opinion, just to make that clear). And the mere fact that Y occurs after X doesn't prove cause and effect, especially when Y happens to men without any trigger all the time.

I will now leave the talk about treating Y to you gentlemen.
 

Mens Rea

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twenty.five said:
[quote="Mens Rea":2bqg2ncx]But don't try come across as some sort of medical authority.

What the hell? I expressed an opinion. You can disagree with me without being an *** about it. My response that you quoted wasn't as polite as it could have been, probably because I was called a tool, but your response to me more than balances it out.

Your anecdotal evidence of stories from these boards aren't that convincing (in my non-medical opinion, just to make that clear). And the mere fact that Y occurs after X doesn't prove cause and effect, especially when Y happens to men without any trigger all the time.

I will now leave the talk about treating Y to you gentlemen.[/quote:2bqg2ncx]


There are very little comprehensive studies on the likes of this. Ultimately there isn't really a great degree of interest for such to be undertaken.

You can mess with a myriad of drugs and substances without clearly published side effects if you so wish. Sometimes we have to work on our own experiences and exercise extreme caution with such things - because noone will care if you do experience an "unpublished" reaction. And, if you follow medicine you'll quickly learn that its usually years behind in such regards.


Anyway, you said you expressed an opinion but you said the following:

I can assure you that your "doctrine system" is fine.

This is all psychological. Topical spironolactone is NOT systemically absorbed. It also has no proper evidence to suggest it works.

Sounds like misguided medical advice to me. Not to mention the disrespectful dig contain therein.
 

damielmillo

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Well....i am an PFS, i left propecia 2 years ago and i have not recover...
i tried spironolactone, Fluridil and RU and i have Androgenic side effects so there is possible to get systemic side effects. I can admit it and this sides are as bad like propecia....
be quiet
 
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