Minoxidil consensus

Oger

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What was your overall opinion on minoxidil? Any success/horror stories? I cam across a similar poll on another forum that was from back in 2006. That poll seems pretty over run with stories of non stop she'd and destruction of hairline. My overall opinion on that poll was that the shed they were speaking of was just the normal male pattern baldness process they were witnessing with little to no adverse effects from the minoxidil. I myself have just started 2x daily application for diffuse poss, but mostly for the hairline, as I have no recession but pretty bad loss at front. I don't want to make the situation worse. So what is/was your story?
 

br1

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I have been using it on my temples for almost 3 weeks now. At first it basically "burned" all the hair there... But now, it (seems) to be growing back.. i.e. the areas seem to be filling in, getting darker.
 

Oger

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I was curious about this, I have heard of the "shed". However I thought mine seemed a little hard.. I initially buzzed down to a 1 to make application and progress tracking easier. But after very first application of minoxidil. I saw ridiculous amounts of very tiny hairs coming out of my head.. I'm glad I shaved down because seeing this she'd would've freaked me put even worse.. was yours immediate as well?
 

Digidako

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I just started using minoxidil again after about six months off and I shed like a dog for the first couple weeks, it was very disheartening. Its been about a month and a half now and I can and my temples are already appearing thicker.
 

br1

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I was curious about this, I have heard of the "shed". However I thought mine seemed a little hard.. I initially buzzed down to a 1 to make application and progress tracking easier. But after very first application of minoxidil. I saw ridiculous amounts of very tiny hairs coming out of my head.. I'm glad I shaved down because seeing this she'd would've freaked me put even worse.. was yours immediate as well?


Yes, I would say like in the first week..
 

dekaz

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I found the foam version to be completely useless, i believe i saw OK results with liquid, no where near recovery, but at least some more hair...though i got bad side effects taking 2ml a day so i stopped minoxidil atm and gonna let the sides clear (burning/tingling feet) and then try 1ml a day, and if that doesn't do it - i'll go agent 47 style.
 

shookwun

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It's ok, but wont stop the progression of hair loss unless you inhibit DHT.
 

Eren

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Minoxidil is something that may work really well, barely or not at all. Point is, the results vary widely per individual. The most recent long-term study I know of is the Olsen et al. (1990). According to their five-year study, regrowth peaks after 1 year. At the third year, there was a slight decrease in nonvellus hairs, albeit not significant. At the 4.5 to 5 years, further decrease was noticed. But this was just on average. There were individuals that still had additional regrowth even at the 5 year mark.

The citation of this study tells us the following (somewhat more elaborate than I state above):

"Patients who completed the long-range follow-up were not
statistically different in terms of baseline age, duration,
or pattern of baldness from the larger initial group (p> 0.15).
The patients who continued with topical minoxidil for
4.5 to 5 years tended to have
lower baseline nonvellus hair counts (p =0.076)
than the short-term group but had a similar amount
of hair growth during the initial 12 months
(p == 0.360).
Hair regrowth with topical minoxidil peaked at
approximately 1 year of treatment with a slight but
not statistically significant decrease in 1-year counts
seen at the 3-year visit (p =0.16, Fig. 2). At 1 year
there was a mean increase in nonvellus hairs compared
with the baseline count of 273.4 (± 157.1) and
that at 3 years, 246.2 ( ± 171.8). At 4.5 to 5 years a
further decrease was noted in the mean nonvellus
hair counts (Table II), which was a statistically significant
decrease from the 1-year nonvellus hair
counts (p == 0.012) but was still a significant
(p <0.001) increase over the baseline count
(206.6 ± 163.3). However, some patients receiving
long-term treatment with topical minoxidil continued
to have an increase in nonvellus target area
counts at 4.5 to 5 years beyond their 1-year counts
(n =9). Similarly, a few subjects, despite continued
treatment with topical minoxidil, had nonvellus target
area hair counts decrease below baseline (n = 4,
-36 ± 40.5).
"

- - - Updated - - -

Minoxidil is something that may work really well, barely or not at all. Point is, the results vary widely per individual. The most recent long-term study I know of is the Olsen et al. (1990). According to their five-year study, regrowth peaks after 1 year. At the third year, there was a slight decrease in nonvellus hairs, albeit not significant. At the 4.5 to 5 years, further decrease was noticed. But this was just on average. There were individuals that still had additional regrowth even at the 5 year mark.

The citation of this study tells us the following (somewhat more elaborate than I state above):

"Patients who completed the long-range follow-up were not
statistically different in terms of baseline age, duration,
or pattern of baldness from the larger initial group (p> 0.15).
The patients who continued with topical minoxidil for
4.5 to 5 years tended to have
lower baseline nonvellus hair counts (p =0.076)
than the short-term group but had a similar amount
of hair growth during the initial 12 months
(p == 0.360).
Hair regrowth with topical minoxidil peaked at
approximately 1 year of treatment with a slight but
not statistically significant decrease in 1-year counts
seen at the 3-year visit (p =0.16, Fig. 2). At 1 year
there was a mean increase in nonvellus hairs compared
with the baseline count of 273.4 (± 157.1) and
that at 3 years, 246.2 ( ± 171.8). At 4.5 to 5 years a
further decrease was noted in the mean nonvellus
hair counts (Table II), which was a statistically significant
decrease from the 1-year nonvellus hair
counts (p == 0.012) but was still a significant
(p <0.001) increase over the baseline count
(206.6 ± 163.3). However, some patients receiving
long-term treatment with topical minoxidil continued
to have an increase in nonvellus target area
counts at 4.5 to 5 years beyond their 1-year counts
(n =9). Similarly, a few subjects, despite continued
treatment with topical minoxidil, had nonvellus target
area hair counts decrease below baseline (n = 4,
-36 ± 40.5)."
 
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