Recent Study On Promoting Hair Growth With Pak1

[Koga]

Could someone with a more scientific background interpret what this study found out about the use of PAK1 for hair loss? It seems very promising, no? Link to the study: https://www.ncbi.nlm.nih.gov/pubmed/28098826

 

[FoucaultII]

Could someone with a more scientific background interpret what this study found out about the use of PAK1 for hair loss? It seems very promising, no? Link to the study: https://www.ncbi.nlm.nih.gov/pubmed/28098826

The research team isolated bioactive compounds from a flower (alpinia) that are believed to block the PAK1 enzymes, whose blocking is believed to correlate negatively with hair loss and cancer.
Well, it seems too good to be true and we know very little about it, to boot.
Nice finding, though.
Well done!
Thnx...

 

[Tracksterderm]

Nice find!

(In vitro )increased the proliferation of human follicle dermal papilla cells by approximately 117%-180% and 132%-226%, respectively,

It is extra nice that the compound works against cancer as well, which should mean extra traction to get it out and to the market.

 

[bigentries]

https://www.ncbi.nlm.nih.gov/pubmed/26537230

Start to rub propolis on your scalp

But everything work in vitro and rats

 

[Stupidon]

 

[Ikkaku]

Maybe we can ask Kane to do it?

And is it possible to add this in Minoxdidil?

 

[tylerduren]

looks fun and inexpensive and doable by most chemists

 

[tylerduren]

http://www.sigmaaldrich.com/catalog/product/sigma/srp5246?lang=en&region=GB

we need money, guniepig and photos

 

[mr_robot]

http://www.sigmaaldrich.com/catalog/product/sigma/srp5246?lang=en&region=GB

we need money, guniepig and photos

£306 for 10 micrograms, nice.

 

[inmyhead]

https://www.ncbi.nlm.nih.gov/pubmed/26537230

Start to rub propolis on your scalp

But everything work in vitro and rats

dermarolling + propolis?

 

[bigentries]

dermarolling + propolis?

Maybe, I'm personally tired of trying these treatments. I already did curcumin and dermarolling to no results

Sigma Aldrich also sells the Cucurbitacin I molecule that's apparently more effective than propolis

 

[Solomon]

JAKS are already here. It "cured" AA, we have photos and studies but they're still not on the market after 3 or more years!

and now we are reading about something completely new, we have no studies, no photos, nothing. It makes me very pessimistic :|
How can we be happy for something when we have no proof when JAKS have shown us everything but still no one can use it...

 

[ahmad029]

http://molecular-cancer.biomedcentral.com/articles/10.1186/1476-4598-13-201
the above study reveals the PAK-1 inhibiting capability of "THYMOQUINON". The same molecule block COX2/PGD2 pathway.
it also ibhibit GSK3Beta which down regulate Wnt pathway. i have also read a study about its inhibiting property against Androgen Receptor.
it also a powerful antioxident.

 

[Calchas]

Scientists tend to ignore that DHT is actually a hair growth promoting substance anywhere on human skin except the top of the scalp(DHT paradox).
We don't need another hair stimulant that works in vitro,we have hundreds of them and none is effective in reversing scalp miniaturization.