Scalp Hair Regrowth In Hormone-treated Transgender Woman

[Armando Jose]

New hair growth in trasgender male/female
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367483/

Furthermore, it would be interesting
to determine whether more scalp hair regrowth occurs
over time as this patient continues hormone therapy.

 

[DHTpolice]

Yes, it works. But this particular case looks a little bit disappointingly, because the scalp wasn't even slick bald. I have seen full recoveries from advanced male pattern baldness to Norwood 1/2 on estrogen and spironolactone, even without finasteride. Usually those who combine HRT with minoxidil see much better results. HRT wakes dormant follicles from sleep, but they are still too short and unnoticeable for an eye. It takes too much time for them to turn terminal. Minoxidil makes them stronger much faster.

This is what HRT with minoxidil can do:

Spoiler: 1

Spoiler: 2

Spoiler: 3

 

[Min0]

everyone who says that baldness is programmed cell and it's inevitable like aging death should go f*** himself, cell death is irriversible.
baldness is not. we already know that estradiol grows hair.

 

[Tano1]

Those pics are the best results I've ever seen. At what cost though? Wouldn't spironolactone basically turn me into a female?

 

[ALightInTheDark]

Basically binding forever and f*** DHT forever + FGF9 estro induced.
So resurrecting hair,wnt signals,lactate and everything else. Cost of this : Your masculinity.
Yay.
f*** MBP. If MBP was a man,I would have murdered him and take 20 years of jail for my hair.

 

[abcdefg]

Hormones are still the most important part of male pattern baldness we know of so far. Androgens and estrogens are huge players in male pattern baldness. It perfectly explains the difference between men and women. Why women at older ages maintain so much of their hair compared to men at that age. Its the cumulative effect of androgens.
Women go bald like men when they grow facial hair and body hair after given large amounts of androgens.

 

[MomoGee]

I understand the excitement with these kind of pics reversing high NWs by messing around with your hormones. But most of us here are trying to get women NOT turn into one.

 

[BaldyBalderBald]

^this, i agree, Finasteride is the max i'm willing to do for hair regarding hormones.

However, this proves one thing, follicles don't die with MBP, but...

Yes, it works. But this particular case looks a little bit disappointingly, because the scalp wasn't even slick bald. I have seen full recoveries from advanced male pattern baldness to Norwood 1/2 on estrogen and spironolactone, even without finasteride...

How can you explain their recoveries is not total ? Back to Norwood 0 like most of women with full temples, childhood style.
Did some of the follicles get lost in their way ? Irreversibliy ? HRT is not a 100% conversion ?

 

[ALightInTheDark]

^this, i agree, Finasteride is the max i'm willing to do for hair regarding hormones.

However, this proves one thing, follicles don't die with MBP, but...



How can you explain their recoveries is not total ? Back to Norwood 0 like most of women with full temples, childhood style.
Did some of the follicles get lost in their way ? Irreversibliy ? HRT is not a 100% conversion ?

PGD2 stacks in bald area. He/She didn't get rid of it.
There is a lot of HRT Trans women who get back their full head of hair after years only

 

[BaldyBalderBald]

PGD2 stacks in bald area. He/She didn't get rid of it.
There is a lot of HRT Trans women who get back their full head of hair after years only

Cool, encouraging...thought it was irreversible

I remember reading a paper that mentionned fibrosis can occur in long-term balding areas of scalp, maybe it's not the case after all.

 

[dr75]

We all know that immense regrowth is possible when you castrate yourself medically. The trick is to reverse baldness without feminizing yourself.

 

[ManinBlack]

2017 and this is the best we got. When will these genius scientists figure out how to regrow hair on a man's head without turning him into a woman?

 

[DHTpolice]

I understand the excitement with these kind of pics reversing high NWs by messing around with your hormones. But most of us here are trying to get women NOT turn into one.

It's possible to get women even as a woman lol.

 

[BaldyBalderBald]

I don't doubt it

I guess what he meant was to get women as a man with a fully functional penis....and a full head of hair.

It didn't work for Garrison tho....

 

[DHTpolice]

I don't doubt it

I guess what he meant was to get women as a man with a fully functional penis....and a full head of hair.

It didn't work for Garrison tho....

View attachment 65776

Mtf in most cases have functional penis, and sexual sides are not that bad really, just need to put more efforts... And always there are options like v****, etc... I think on antiandrogens my libido and sexual functions dropped to what they were at 13-15 years old.

 

[cocona]

PGD2 stacks in bald area. He/She didn't get rid of it.
There is a lot of HRT Trans women who get back their full head of hair after years only

PGD2 is a result of gene expression. Gene expression is a product of the environment the cell is in. Basically the environment signals PTGDS to be produced in overabundance. DHT will do this to an extent but losing hair does it more. This is why PGD2 levels go through the roof on high norwoods. Getting your hair back in areas will reverse this. (Not proven, just logic, since the signaling will be different cause hair is there now.) Gene expression is caused by signaling to the cell to produce more of the enzyme(The transcripted gene). Nuclear Factor Kappa B is an example of a protein which regulates the transcription of DNA.(PTGES and PTGE2 specifically; the enzymes responsible to turning PGH2 to PGE2.) Another cool one: Hypoxia increases transcription of PTGES as well. My point is that if you can get the hair there it should stay provided you can prevent further degenerative destruction induced by DHT.

 

[mompo]

Do you think mesotherapy with Estradiol and Spironolactone can be possible and effective?

 

[bigentries]

Its the cumulative effect of androgens.

Some people claim the cumulative effect has nothing to do with it. Apparently, older eunuchs given testosterone tend to lose hair faster than younger eunuchs. In that case, age also plays a factor, which could also explain why bald male teenagers are so uncommon

It pisses me off that male pattern baldness, true male pattern baldness is getting reversed right now and no one seems to be eager to study it. Yes, testosterone and estrogen obviously play a huge part, but we can't just dismiss other pathways involved that could be replicated without hormone manipulation