Skin discolouration from Xandrox

[aussiedavid]

I have been using Xandrox for the past 18 months and prior to that a compounded solution of 7% minoxidil and 0.025% Retinoic Acid. Over the past 18 months I have noticed that the skin along my hairline has lightened considerably and I now have a visible difference in pigmentaton between the area that the Xandrox is applied to and my forehead. There is a distinct line separating the Xandrox area from the rest of my forehead. I figure it has to be one of the ingredients of Xandros that is causing this. Maybe the retinoic acid? Perhaps the axaelic acid? I did not have this problem when I was using the compounded mix of 7%minoxidil and 0.025% Retinoic Acid. The skin where the Xandrox is applied is blemish free and looks fantastic. I either need to find a skin care product that will have the same effect on the rest of my forehead, or consider stopping the Xandrox. I also apply 5% spironolactone cream to the same area.

Any suggestions as to what ingredient may be causing this?

Is anyone else having this problem?

I've got a referral to see a dermatologist, but my appointment is over a month away.

 

[diffuse propecia]

It is the azelaic acid, it is also used to reduce skin pigmentation. you can find it in skinoren (an acne cream) for facial application.

 

[Petchsky]

What's your full regimen Aussiedave? and how's it working out for you?

 

[aussiedavid]

Thanks for the info. I'll try applying azelaic acid to the rest of my forehead and see if that works.

My current regime:

1/4 Proscar/day
2 x 160mg Saw Palmetto/day
Morning and evening: 1/2 ml Xandox 5% (with Azelaic Acid and Retinoic Acid). Applied to rear and mid scalp. 15 mins later I apply 5% spironolactone Cream to hairline.
Morning and evening: 1/2 ml Xandrox 15 Plus. Applied to hairline area. 15 mins later I apply 5% spironolactone Cream to hairline.
2 times/week I shampoo with Nizoral 2% Shampoo. On the other nights I use Neutrogena T/Gel Shampoo and conditioner.

My Results: I've been using Finasteride for approx 12 years now, along with various strengths of minoxidil solution. I have a lot more hair than both of my brothers who are of similar age and who don't use anything to prevent hair loss. My problem area is the temporal region. I changed from a compounded 7%minoxidil + retinoic solution to the Xandrox 15 around 18 months ago. In that time I have suffered further hair loss in the temporal area. I don't know if it's the xandrox that's caused it, or if it would be worse if I wasn't using the Xandrox. Maybe the spironolactone is not doing me any favours. This will sound weird, but there is one solo hair that comes and goes over about a 4 month cycle in a bladed area of my temoporal region. It always comes through as a thick black hair, grows to about a one cm in length, then falls out. Since I have been using the spironolactone, that hair has not been seen. It has been doing it's cycle for as long as I've been bald in that region. I find it unusual that it's stopped appearing since I started the spironolactone cream. It makes me wonder if the spironolactone has actually accelerated the loss in my temporal area. The other thing of note is that I have had accelerated greying of my hair since I started the Finasteride. Neither of my brothers have any grey hair, yet I am almost completely grey now.