Gadgetine

Exploring The Hormonal Route. Hair=life.

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Ikarus

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I'mme said:
I guess I'd again be able to become normal. I don't know if I'm originally an introvert or I just turned one BC of Hair loss. But it gave me bouts of depression, so I'd like to think I'm ambivert. I hope I can be normal again.

You're quick? Still you lost huge density. You can't add growth stimulant for reasons otherwise your progress can be fast.
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I was reasonably quick, meaning that there was no hesitation for me to use such a regimen.
 
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Ikarus

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Itsnoahkennedy said:
I've gone from eating once a day to eating like 5 meals a day, i am so HUNGRYYY. I could eat an elephant frfr lol.

Btw @Ikarus i have the same white sandy type dandruff you were talking about a few weeks ago. did yours go away ?
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Mine did go away, soon after I started spironolactone and estradiol; maybe in the month of April it went away.
 
Yar

Yar

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Itsnoahkennedy said:
I know your pain man, i started losing mine later than you, at 17 years old, but the stress of balding has taken a toll on my mental health. It became an obsession to get my hair back, i spent a lot of money on doctors who did no help, some "hair specialist" even scammed me for $2,500 and i knew it might be a scam but that's how vulnerable i was because i was desperate. I tried Finasteride which did nothing. I tried Dutasteride which did nothing. i tried topical minoxidil which maintained for a while but eventually did nothing. For the first 3 years i was so stressed out that towards the end when i knew none of those meds were working in my body i would go into full blown psychosis where i would feel panicked with anxiety and have many hallucinations where i would feel like i am having a bad acid trip. It sucked me dry of emotions and i can't feel enjoyment in anything at all no matter what it is, people said get out and travel, so i traveled the world and got no enjoyment out of it, and i think balding has altered my personality in a way that i am bitter inside and i also lost my long time girlfriend because of it (i assume). I live in isolation to this day because of it. i don't go outside or talk to anyone unless i have to. i guess it depends from person to person but balding can literally destroy ones life. HRT is the last hope for myself, i said the same, i choose side effects over depression because i don't want to feel like a piece of sh*t anymore.
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do not be upset, you will return your hair, half a year a year of feminizing drugs and most importantly check any information, with many preparations finasteride or dutasteride I would not even try, even in combination with estrogen and antiandrogen. My preparations are female drugs, estradiol, progesterone, cpa, spironolactone. After adding finasteride to the mode, my biceps increased, my back was rounded, the smell of male sweat increased. The hairs on the inside of my arms reappeared. It became clear then that finasteride and dutasterid take bodybuilding Dera, in order for more testosterone to work, less DGT. Therefore, I do not use them because the temples at FTM arise due to testosterone injections. And my task is to overgrow the temples. I do not understand why the bridge takes drugs for bodybuilders Finasteride and Dutasteride!
 
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Father_of_Shiseido

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Yar said:
do not be upset, you will return your hair, half a year a year of feminizing drugs and most importantly check any information, with many preparations finasteride or dutasteride I would not even try, even in combination with estrogen and antiandrogen. My preparations are female drugs, estradiol, progesterone, cpa, spironolactone. After adding finasteride to the mode, my biceps increased, my back was rounded, the smell of male sweat increased. The hairs on the inside of my arms reappeared. It became clear then that finasteride and dutasterid take bodybuilding Dera, in order for more testosterone to work, less DGT. Therefore, I do not use them because the temples at FTM arise due to testosterone injections. And my task is to overgrow the temples. I do not understand why the bridge takes drugs for bodybuilders Finasteride and Dutasteride!
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I think the laws of science are different for Russia. Fina/duta aren’t the body building drugs elsewhere.
 
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Father_of_Shiseido

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Itsnoahkennedy said:
I take 0.75mg Oestrogel 17b-estradiol once per day. it's half life is 36 hours, so 1 dose of 0.75mg will last for 72 hours in the body. 72 divided by 24 hours = 3 days. 3 divided by 0.75 = 2.25mg estradiol per day after building up in the blood.

i hope i did that right lol
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You had the feminine face before starting hrt?
 
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Stephen788

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Itsnoahkennedy said:
I take 0.75mg Oestrogel 17b-estradiol once per day. it's half life is 36 hours, so 1 dose of 0.75mg will last for 72 hours in the body. 72 divided by 24 hours = 3 days. 3 divided by 0.75 = 2.25mg estradiol per day after building up in the blood.

i hope i did that right lol
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Did you get gyno on that small amount your taking?
 
LEXUS

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Itsnoahkennedy said:
@LEXUS I think it would be benificial for you to read this paper written about CPA before you continue with taking high doses of the drug (read paragraphs from the right side to the left side starting with the introduction)
This information is important to keep in mind when you are taking CPA without doing research on it's phase trials. (im assuming you haven't read it before)

Title: The DNA damaging drug cyproterone acetate causes gene mutations and induces glutathione-S-transferase P in the liver of female Big BlueTM transgenic F344 rats.

Although the study was done on rats liver, it is still good information to have when you are considering very high doses of CPA. The term liver damage includes cancer, cell/gene mutation, high liver enzyme and the list goes on.

https://academic.oup.com/carcin/article-pdf/19/2/241/19258155/190241.pdf

See - "Results Mutagenesis assay The experiments performed in this study reveal that CPA was a mutagenic compound in rat liver. In experiment 1, performed with one animal per dose and expression periods of 11 and 22 weeks, a dose of 100 mg CPA/kg b.w. was found to increase the mutation frequency determined in the controls by a factor of almost 4, while doses of 25 and 50 mg CPA/kg b.w. were ineffective, with the possible exception of 50 mg CPA/kg b.w.

11 week assay time (Table I). Experiment 2 performed with five animals per dose group and an expression period of 6 weeks revealed a dose dependent increase of mutation frequency at doses between 75 and 200 mg CPA/kg b.w. (Figure 1, Table I). Mutation frequencies determined at doses of 25 and 50 mg CPA/kg b.w. did not exceed those determined in control animals. For interpretation four common dose–response models were employed to fit the data.

For the 6 week assay, Figure 1 presents a plot showing the observed proportions of mutants of the individual rats, the pooled proportions and the four dose–response models fitted. The linear model (Model 1) produced the worst fit to the data. Models 2 and 4 are better than Model 1 and indistinguishable from each other. The linear E-NOEL model (Model 3) fits the data even slightly better than Models 2 and 4. The overall lack-of-fit statistics support these observations. For Model 1 the deviance has an associated p value of 0.03 indicating" (page 242)
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you do not read carefully. I wrote that I now take only 16 mg of cyproterone. The only problem with cyproterone is that it destroys estradiol.
 
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Ikarus

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Stephen788 said:
Hi mate
Do you reckon you’ve had any sides at all since being on bica?
How’s your hair doing also.
Cheers.
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Side effects have cut down drastically compared to when I was on spironolactone. On spironolactone, I would get the unpleasant effects of it being a diuretic such as: tiredness, weakness, nausea. Gynecomastia has worsened, which is because bicalutamide raises E further compared to before; if you are not on estradiol, you are fine.
 
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Stephen788

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Ikarus said:
Side effects have cut down drastically compared to when I was on spironolactone. On spironolactone, I would get the unpleasant effects of it being a diuretic such as: tiredness, weakness, nausea. Gynecomastia has worsened, which is because bicalutamide raises E further compared to before; if you are not on estradiol, you are fine.
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Cheers mate. I am excited to just get started. I just want some regrowth. This is the best hrt drug for me because it doesn’t effect androgens like the others. I want to be on this long term so fingers crossed it works for me.
 
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Ikarus

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Stephen788 said:
Cheers mate. I am excited to just get started. I just want some regrowth. This is the best hrt drug for me because it doesn’t effect androgens like the others. I want to be on this long term so fingers crossed it works for me.
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Dutasteride + Bicalutamide + Oral Minoxidil; will that be your regimen?
 
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I'mme

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Ikarus said:
Dutasteride + Bicalutamide + Oral Minoxidil; will that be your regimen?
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This is the regimen I've been advocating for a month now. That is the best regimen with minimal sides vis-a-vis benefits.

  • DHT blocker - check
  • Test and other androgens blocker - check (I know bica doesn't directly block it)
  • Growth stimulant - check. Pretty powerful one.
Just need to add metformin or raloxifene for gyno and the person should be done with this f*****g disease. Or maybe I'm just being delusional.
 
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