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Very true, nice post. Yes, if you want to remasculinize, you need to drop bicalutamide and use a topical anti androgen.
Exploring The Hormonal Route. Hair=life.
- Thread starter bridgeburn
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Unusual hairline on Neil Young. He probably washes it Down by the River....
The chest stopped hurting, it only hurt for a few minutes, there were no signs of gynecomastia. I found myself resistant to gynecomastia
But I still need surgery, because I plan HRT next year to resume growth
Wish I wasted time on Finasteride. My hair has suffered a lot, now it's not enough just to keep it - I need an increase in density
But I still need surgery, because I plan HRT next year to resume growth
Wish I wasted time on Finasteride. My hair has suffered a lot, now it's not enough just to keep it - I need an increase in density
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Density, volume and better texture with a long anagen phase so one can grow one's hair long. I am achieving all four of those. It's a weird feeling because on one hand, it's just a matter of time but you never know or at least you fear that the hair conks out before you reach your goals but I have pretty much done that. I would go back on maybe 50mg to 100mg of spironolactone just to see if that flips any more receptors. It's weird how AA's and estrogen can cause different things so often.
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I am also thinking that adding spironolactone might help with some or all of the hypertrichosis.
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Do spironolactone receptors and estrogen receptors overlap? I am just wondering why estradiol together with spironolactone would be useful. I have a feeling that spironolactone and estradiol are synergistic. I am starting back to 50mg daily to see if it makes my beard less scratchy which annoys me to no end since I added oral minoxidil. I probably should have just reduced my dosage of spironolactone but I shall see if there are any sides from using only 50mg and to see if there's synergy.
ive been taking 50mg and 1mg estradiol + .75mg estrogel for 2.5 months and no bad sides yet and am seeing minor growth on the hairline. Im really looking to increase overall density but that looks like it could be achieved at the 6-8month mark
I heard that people were losing ground trying to maintain the result obtained by Spironolactone with Bicalutamide
spironolactone has an estrogen-like effect. It may not be possible to maintain estrogen results with Bica, especially hair quality and texture
In a mouse study, we see that Bicalutamide does not completely prevent the effects of DHT, which I can see from the fact that I still have a small amount of acne and sebum. Possibly needed dosages of 150mg, which are comparable to castration
Ikarus also complained about his hairline, although he uses Estrogen with Bicalutamide. So everything may not be as easy as it seems at first glance ...
In general, this is all theory. I intend to test everything in practice
spironolactone has an estrogen-like effect. It may not be possible to maintain estrogen results with Bica, especially hair quality and texture
In a mouse study, we see that Bicalutamide does not completely prevent the effects of DHT, which I can see from the fact that I still have a small amount of acne and sebum. Possibly needed dosages of 150mg, which are comparable to castration
Ikarus also complained about his hairline, although he uses Estrogen with Bicalutamide. So everything may not be as easy as it seems at first glance ...
In general, this is all theory. I intend to test everything in practice
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It's funny. I took one on one day and I became ravenously hungry for NaCl.
Ikarus also started 5mg oral minoxidil because he wasn't 100% happy with his results from bica and estradiol alone and had really great results, estradiol and minoxidil seem to work great together, whether oral or topical.
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Unfortunately, only HRT will help you. Bicalutamide will only stop baldness, but you need to grow your hair. You can start right away with 50mg Bicalutamide + 2-4mg E, and then try to support the result with 75-100mg Bicalutamide. You will also have to undergo surgery to remove gynecomastia.
Bicalutamide only stops and slightly improves hair quality and thickness, just like castration. Estradiol is responsible for any re-growth, without it it will not be possible to return the hair. I want to try Estradiol, but give it up and try to keep the result on Bicalutamide
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I sadly don't have access to bicalutamide and HRT. Maybe Bicalutamide in a few months, but for HRT, I would need to start a job and that would be pretty hard in my current position.
Life is so unfair.
Any thoughts on using cyclodextrins as a topical E2 delivery mechanism to avoid systemic effects?
Drug Targeting to the Hair Follicles: A Cyclodextrin-Based Drug Delivery - PMC
www.ncbi.nlm.nih.gov
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The cheapest option for e2 is lena's injectable. If feminizing sides aren't a concern for you, then monotherapy could be an option. It depends on the dosage, but around £100 will get you a years supply.I sadly don't have access to bicalutamide and HRT. Maybe Bicalutamide in a few months, but for HRT, I would need to start a job and that would be pretty hard in my current position.
Life is so unfair.
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Your temples are still very good. Honestly better than mine after a full year of treatment. I wouldn't worry about your temples. The top of your head is worse, but I've always heard anecdotally that that area is easier to regrow than temples.