Recent content by Loopydude

Testosterone vs. DHT Testosterone and DHT do the same basic thing, in that they both bind to androgen receptors and affect gene expression. DHT does this much more potently than testosterone. Because of this, there may be some differential in their respective functions. From what I...

minoxidil vs. finasteride Nobody is sure quite why minoxidil causes hair growth, but it is thought to increase the lenth of the growth phase of the hair cycle. Finasteride lowers the production of the androgenic steroid DHT, which is thought to be the most important hormone driving the...

urination I had this experience (more frequent urination) on finasteride. I also had another, rather embarassing problem: The old wet spot on the front of my khakis. I'd take a whiz, shake like crazy, squeeze, shake again...no use. Five minutes later, it looked like I peed myself. A few...

Response to Bryan Heya, Bryan, I guess I was under the impression that microbial infestation playss a big role in seborheic dermatitis (Malassezia yeast infection appears to be the most prevalent problem), and so keto's antifungal properties go a long way toward explaining its effects on...

What can you say? Not much, unfortunately... On the simple basis of principle, I have to agree with maddoc. Not only is there no good data, there's really none at all. Sorry for the confusion about antisteroidogenesis swamping androgen antagonism: I was thinking about systemic keto, the...

GAAAAHH That pic...I'm going to have nightmares tonight...

Heh This thread is seriously funny. Somebody should develop the idea into a comedy routine. :)

Good luck You never know. Butt-hair cloning might be the wave of the future, and could save your *** someday. I'm a little concerned about the potential cancer-promoting effects of growing ***-skin cells in culture, but as it is "where the sun don't shine", maybe the risk of ***-skin cancer...

*** wig Might I suggest and *** toupee? I know, I know, nobody wants to wear a wig. Seriously, though, *** toupee technology has really advanced in the past few years. Many of the higher-end models are made with real, human *** hair that is color-matched to your own hairy *** to blend...

Think about anabolic steroids... Androgenic anabolic steroids cause you to lose fat and put on lean muscle. They mimic endogenous androgens in that respect, only they're more powerful. DHT is the most potent androgen your body makes. If you reduce the amount of DHT in your body, doesn't it...

Just part of getting old This doesn't seem so mysterious to me. You get older, you start going bald. What changed? When you were 20, your body was making as much or more DHT as now, when you're, say, 40. It would appear some people are genetically programmed to respond increasingly to...

Some points Hey, Brian, In vitro binding assays are great for some things, but it has to be understood that context is everything, and it's not unusual for such assays to give spurious results. They have to be followed up with more careful analysis, ultimately things like radioligand...

Hrm... I never got the impression there were any pissing contests here. I call it healthy debate. I don't think of debate as a brainiac contest, I think of it as a good way to get at the facts. I guess it's just that discussions of this type are so common where I work, I take for granted...

Reply to da bomb... It's an interesting question to ponder. The simplest reason to say 0.5mg/day finasteride. is effective is that 1mg/day is really more than you need. But the story might be a bit more complicated than that... Think of it this way: Let's just argue that 1mg finasteride/day is the...

5AR and finasteride Finasteride is a "suicide inhibitor" of type-II 5-alpha-hydroxylase; it binds irreversibly to type-II 5AR, meaning that once bound, both molecules are effectively destroyed. It takes your body a while to synthesize new type-II 5AR molecules. Since a 1mg dose of finasteride...