Recent content by New dimonesion

According to this biotech company, Oxy133 should be risk free. But FDA would not allow trials unless tests on mice have no trace of cancer.

Don't know whether it will work or not, however hedgehog pathway seems to reverse hairloss. Yesting was halted by P&G in 2007 due to potential cancer risk.

https://experiment.com/projects/can-hair-loss-be-reversed-with-oxy133-a-sterol-based-drug-candidate This crowdfunding is meant to test a compound which targets the Sonic Hedgehog Pathway.

https://experiment.com/projects/can-hair-loss-be-reversed-with-oxy133-a-sterol-based-drug-candidate This crowdfunding is meant to test a compound which targets the Sonic Hedgehog Pathway.

Should anything positive was revealed during the conference, I guess that the news would have already reached us.

Thanks for the info and effort, Pls keep me posted should you get any feedback.

Thanks, I asked about jak inhibitors as Aclaris has pushed with trials for Androgenetic Alopecia. I don't expect an answer from you, but I woul really appreciate if you can ask some of your colleagues whether they have any info.

@Insider, Do you know anything about Aclaris phase 2 for Androgenetic Alopecia? Or could you see if any contact of yours can supply any info?

What makes you think that Aclaris will make an update regarding Jak for Androgenetic Alopecia? Is there an official quote?

Thanks again for the info. TBH, when it comes to JAK, I have some hope because somehow during the interviews, both Angela Christiano and Aclaris CEO DR Neil Walker have made some slip ups with regards to male pattern baldness.

Basically, we could farm them, but get no hair in return :)

Thanks for the detailed info. Could you kindly mention the companies involved with dermal papillae regeneration, or something of the sort? Also, would JAK inhibitors effect dermal papillae?

I have been pondering whether hair follicles, die out due to male pattern baldness or just remain miniaturized and producing tiny microscopic hairs undetectable to the human eye. Can anyone provide some info pls?

I'm still on the lookout for Aclaris. Jak might pove to be the real deal. That is, as long that hair follicles don't really die out in people with male pattern baldness.

What makes you so sure that JAK (Decernotinib?) will work for Androgenetic Alopecia?