I won't go into much detail into my past history with antiandrogens (you can read my previous threads for that). Basically 0.5mg Dutas (Dr. Reddy's) daily is not really doing the job. I was thinking of taking 0.5mg twice daily to see if it has any effect. I've read that while doing research they've administered patients with upto 2.5mg Dutasteride and they didn't really have a lot more sides than people on 0.5mg. I don't really have any sides on Dutasteride right now either so I'm thinking I can maybe increase the dose and see how it goes. The main thing I'm concerned about is the long term affect of Dutasteride on the liver.