2 year, 3 month update from an old Vet.

bombscience

Senior Member
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Anyone remember me?

After over 2 years, my hair is still thinning. I have to admit that my treatments have probably slowed this process down considerably, but the inevitable is still coming my way. Over the last year, I have been using the strongest treatments, with minimal success.

My anti-hairloss cocktail for the last 12 months has been:

Xandrox 15% 1 or 2 times a day.
0.5mg Generic Dutasteride daily
2.5mg Generic Finasteride every 2 or 3 days.
T-Sal/Nizoral Shampoo every other day.

The Story: The frontal area of my scalp has progressed thinning more than the crown, which has lost the least. My first year of fighting balding was experimental, and I finally arrived at a consistant regimen last July. After re-introducing minoxidil (in a 15% concentration) I noticed a 3-4 month thickening of my hair. The next 6 months were mostly maintainence or a slow progression of thinning. For the past 3 months, my hair has begun to thin at an increasing rate.

In Summary: After over 2 years, my hair is about 20% thinner than when I began treatment. This is probably a lot better than it would have been if I had never done anything.

My Thoughts: I have a feeling that DHT reduction isn't working for me, or my folicles are highly sensitive to any remaining DHT in my bloodstream. I attribute any success that I've had to minoxidil. I know it's working because for the 3 months before i began Xandrox 15% I stopped using minoxidil, only to induce the fastest shed I've had in over a year.

I'll try to post pictures in the next week. I haven't been frequenting the forums too much, but if anyone has reccomendations on where to go from here, I'd love to hear them. I'm thinking about using spironolactone on the front of my head, but it's pretty pointless considering I have a mega-dose of DHT fighters.
 

Cornholio

Established Member
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Damn, I hate to hear stories like that... progression while on big gun treatment. :( You have more posts than TynanW!!!

I think that there is reason to think adding a topical androgen receptor blocker might give some additional benefit... on dutasteride .5mg/day there is still dht being produced in the scalp and serum testosterone goes up. spironolactone 5% or Fluridil makes sense (as they directly block the androgen receptor, while your dutasteride/finasteride/azelaic acid are directed at the 5AR enzyme).

Other additions might include higher doses of dutasteride (unstudied beyond 6 months, so some risk), addition of copper peptides like tricomin (not studied in combo), switching to retin-a/minoxidil combos (xanadrox nighttime), and revivogen....

I think that you're right... people who progress on treatment have a stronger tendency (sensitivity) to dht triggered male pattern baldness and may need different treatment than others... Hopefully some combo of available treatments will help.
 

bombscience

Senior Member
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7
Corn,

Thanks for the feedback.

I have flirted with the idea of Fluridil, but I haven't heard many success stories. The turnoffs about Fluridil are it breaks down with water (found in minoxidil) and I'd have to order it from overseas (expensive). Twenty months ago I tried spironolactone for about three months without noticing anything (not long enough to show results.) I feel it is a weaker, less effective treatment with most, so my aggressive balding wont miss a beat if I try it once more.

I have heard nasty rumors about Dutasteride actually inducing frontal loss. I am really concerned about how fast the front of my dome is thinning in recent months.
 

Bismarck

Senior Member
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If you can stand the sides / risks - go for oral spironolactone. Fluridil isn't strong enough I think.
 

bombscience

Senior Member
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The Cunnilinguist said:
If you can stand the sides / risks - go for oral spironolactone. Fluridil isn't strong enough I think.

I dont think that type of hormone treatment is what I'm looking for. I haven't had any side effects with everything I'm taking right now but I dont trust a drug that is use for sex change ops. ;)
 

Petchsky

Senior Member
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13
I remember you and actually wondered how your hair was getting on not to long ago. Good to hear from you Bomb.

The story goes on... I think Copper peptides could possibly help. You have the best drugs for blocking DHT and use the strongest minoxidil, so maybe CP's (SOD) will help your scalp and tackle hairloss from a different direction than DHT. There is still enough time for the front to turn around and start producing new hairs.

How you feel about your hairloss now compared to two years ago?
 

powersam

Senior Member
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18
after trying what are basically the most powerful treatments available and coming up short, wouldnt it be advisable to look for other reasons for your hairloss? while using dutasteride and finasteride there is no way dht can be the problem and most hair loss treatments work along that pathway. Remember though its often said that 90% of hairloss is caused by male pattern baldness, this is a figure given to us by dermatologists who look at your head for 10 seconds then proclaim male pattern baldness. Go get your thyroid levels checked dude, and i would also advise having a glucose tolerance test done. hairloss does not always have to be androgenic alopecia.
 

GourmetStyleWellness

Senior Member
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6
Bomb -

Welcome back.

Forgive me for asking what is probably a really dumb question, but why are you doing that incredibly weird dosing regimen with the finasteride and dutasteride? Was there some sort of actual solid reason for coming to the conclusion that it would help to take 2.5mg of finasteride every 2 to 3 days? And finasteride plus dutasteride?

You know me. The scientist in me says "Why isnt he taking 1mg Propecia daily?" I guess I just haven't heard a single logical reason for people who double up and skip days. I also haven't heard a single person doing it say they've seen better results. Only heartache.

I've heard the speculatory theories about half life. That's all they are. I haven't seen a single published study state that skipping days and doubling up is a smart move. Even in the custom dosage studies they still keep a consistent dosing schedule of once a day.
gourmetstylewellness.com
 
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