21 Years Of Finasteride/ Dutasteride ( Since 1998, Duta Since 2002).

[jamesbooker1975]

Was replying to the other guy, not you man.

You know this sh*t is poison which I'm glad you do.

Sorry, to many replies. Glad people appreciate this post, make me really feel good. At least, I can use this stupid thing I did to help others

 

[michel sapin]

and dutasteride doesnt cause you puffy nipples ? or lump ?
Just some bad chest form ?

and fina didn't maitain your hair ?

 

[sunchyme1]

No, but I train 5 times per week ( gym plus Martial Arts ) . I eat extremely well. First thought that, for example, the liver enzymes was caused cause high protein diets, but the last lab test, almost 3 month after I dropped from 7 caps per week to 2 caps per week, my ALT and AST drop significantly for fist time .

I have v low body hair in the entire body and also my face hair . Once since I noted, since it reduced Dutasteride and take examestane, is that I have to shave more often .

So, my body don't look like a mess but my hormone levels are. Should be nice if others that have being taking for so long this kind of meds show they bloodworks, will be really interesting. For what I an read, other guy on this post put that with Finasteride his progesterone levels was almost 0. Wonder, for example, how many people on Finasteride check his progesterone levels.

as a pharmacist, how come you didnt realize how bad these drugs were for you a long time ago? and continued to keep taking them for 20 years?

 

[jamesbooker1975]

so you dont have baseline readings for any of those just the most recent ones once you had problems. Without the baseline readings how do we know those didnt develop naturally?
Well you took oral spironolactone, dutasteride, and finasteride all for significant periods of time. Those issues could be from any of them so it certainly doesnt prove out that finasteride or even the dutasteride you took that long caused this. Although I guess dutasteride is the one you used the longest.

I do have baselines one before I started with Finasteride, everything was fine. I also have another bloodwork done on 2003 and everything was going wrong, including an Espermograma that just got better when 4 years ago I used anastrozol .

Again, I was a groupie ! and idiot. So it I read that my liver enzymes where high my reaction was " ok, I eat to much protein, could be that " It my testosterone was in the rank but not for my age I say " well, it is in the rank after all " If I had low libido I say " better, I can be more concentrate in my studies " Etc, etc, etc.

This post is, Look what I did , look what it happen, "you should not cut your foot cause you have a Infected nail" . If you believe beyond all the new studies and evidence that you can reduce an natural hormone that is in the normal limits 70 or 90 % without creating side effects, it is up to you.

There are not many people out there who used Dutasteride for so many years, I bought it from Switzerland before was even approve in USA, back in 2002 thanks to a Germany guy that I met in hairlosshelp in 2001 ! You can say " this guy is an a**h**, this med are totally fine " so it really have none sense to read this post if you think that way. There are many, many others that are more open mind to others people experience who care about this post and the dozen of studies that prove it.

 

[jamesbooker1975]

as a pharmacist, how come you didnt realize how bad these drugs were for you a long time ago? and continued to keep taking them for 20 years?

Most of the studies are pretty new, for example the one that prove that increase cholesterol and liver enzymes. Not body teach you this on the university, doctors still prescribe it, etc. And again, I was a groupie, I was to afraid to loose my hair cause the bad a**h** hair transplants I got in Argentina ( never get one here ) .

 

[MaxPayne3]

Dutasteride will not, probably, give you gymecomastia but remember it will also f*** your cholesterol levels, neurohormones levels and livers Enzymes will increase.

I will handle with them. I feel more bad if I'm loosing my hair.
My plan is to take 1 cap every other day, not like you that took 1 cap every day.

 

[jamesbooker1975]

and dutasteride doesnt cause you puffy nipples ? or lump ?
Just some bad chest form ?

and fina didn't maitain your hair ?

Just some bad chest form, like fatty. Keep in mind I train really hard on the gym since 14 and I noticed that only two years after I started with finasteride.

 

[jamesbooker1975]

Im still not convinced that if you stuck to something like finasteride you would have all these issues. The only big issue finasteride has is it shouldnt be changing neurosteroids at all. Of course merk will never redesign or change it to avoid that, but it should be that the pharma companies go back and fix problems with earlier drugs.

I can not post links cause I am "new " here. On this post (search it on GourmetStyleWellness ) you will find the studies :
"Propecia's devastating effect on neurohormones"

 

[jamesbooker1975]

But spironolactone is more effective than finasteride, even if it doesn't decrease testosterone levels. MtF women take it for growing boobs, this is a side effect that dutasteride doesn't have, or at least with less probabilities.
I think you can't blame DHT inhibitors if you mistake your treatment and it's clearly that spironolactone is not what you needed.


Systemic absorption is more effective through topicals because the substances bypass the liver, so the side effects would be much more.

Again, only used spironolactone oral for 7 month back in 2001/2002 !!!!!!
Oral minoxidil, for example, is not more effective than topical minoxidil. It have tons of more logic to delivery a drug via the scalp and not the mouth !!!!

 

[jamesbooker1975]

Just some bad chest form, like fatty. Keep in mind I train really hard on the gym since 14 and I noticed that only two years after I started with finasteride.

I will handle with them. I feel more bad if I'm loosing my hair.
My plan is to take 1 cap every other day, not like you that took 1 cap every day.

My advice, since the almost 5 week half life of dutasteride and how potent it is : start with 1 cap per week, give it at least 6 month. Keep in mind that even one cap every other day will inhibit more DHT than 1mg finasteride daily.

 

[jamesbooker1975]

Here, for example, we have an study done in 2015 showing that finasteride actually DECRESE testosterone :
Finasteride, not tamsulosin, increases severity of erectile dysfunction and decreases testosterone levels in men with benign prostatic hyperplasia :
https://www.ncbi.nlm.nih.gov/pubmed/26053014

 

[Razzabo]

Here, for example, we have an study done in 2015 showing that finasteride actually DECRESE testosterone :
Finasteride, not tamsulosin, increases severity of erectile dysfunction and decreases testosterone levels in men with benign prostatic hyperplasia :
https://www.ncbi.nlm.nih.gov/pubmed/26053014

Pro finasteride users will never show or link studies to this. Or they will argue only the 5mg dose lowers testosterone for BPH.

It's a flat dose response.

 

[jamesbooker1975]

Pro finasteride users will never show or link studies to this. Or they will argue only the 5mg dose lowers testosterone for BPH.

It's a flat dose response.

I know, I was one of them ! . 5mg and 1 mg inhibit almost the same amount of DHT. But you are right, they will not understand.

 

[abovedagame]

abovedgame, thanks for your reply.
Yes, but like I said, no DHT since it not available here.
First at all, may stupid doctors only check if the testosterone levels are in the range, but most of them do not check your age ! cause you need another table to check it. So my testosterone levels, check at 33 ( 6 years ago ) was in the range, but if you use the variable age, was a 60 years old man levels !
I have a daugther now and to finally get my wife pregnant ( after a year of trying ) I took Arimidex for 3 month . By that time, I was still a finasteride/ dutasteride groupie

Yes, finasteride is safer, first at all, for what I know, finasteride do not mess with your liver. But, again you can not lower 70% of on hormone without having side effects.

But even so, if you want to use it, CHECK your DHT levels, may be they are high and you can download to a certain levels where it will not give you side effects but you will also have to check your estrogens levels, cause it ying/yang . DHT also compete against estrogens. So inhibit DHT will cause estrogen dominance so an anti aromatase could be a must. So it is a real " surgical " job to do .

But keep in mind, that alpha reductase it in a lot more reaction than simple create DHT.

Thank you for the response.

Have u ever suffered from scalp inflammation? What did u do to combat it? Thanks

 

[jamesbooker1975]

Thank you for the response.

Have u ever suffered from scalp inflammation? What did u do to combat it? Thanks

No, well I had folliculitis decalvans but that is another story.
One thing that many people don't count but Dr Lee use it in all his xandrox versions is corticoids ( he used dexametasone ) . I suggest you an small amount of mometasone one time per day is the newest corticoid . Corticoids, as it work on asthma , besides reducing inflamation, I bet that they block, in some way, the CTRH2/prostaglandines pathway of male pattern baldness.

 

[sunchyme1]

No, well I had folliculitis decalvans but that is another story.
One thing that many people don't count but Dr Lee use it in all his xandrox versions is corticoids ( he used dexametasone ) . I suggest you an small amount of mometasone one time per day is the newest corticoid . Corticoids, as it work on asthma , besides reducing inflamation, I bet that they block, in some way, the CTRH2/prostaglandines pathway of male pattern baldness.

this stuff is no good for long term skin damage though right?

 

[jamesbooker1975]

this stuff is no good for long term skin damage though right?

Actual, newest corticoids like mometasone are design for daily use in many skin disease ( for example atopic dematitis ) . If you do not use to much, if you do not have an injury on your skin, etc, should not produce side effects.

 

[jamesbooker1975]

It's good to yell and sh*t. But what's the solution ? Lose my hair and keep my hormones within their natural range ?
f*** that.

lol, you will loose more than hair . Go the damn topica route !!!!!!!!

 

[The Baldy Man]

Too bad there are no topicals nearly as effective as oral finasteride, and the topicals that do show promise go systemic anyways. If you forego oral finasteride in favor of a topical route, your topical route may soon be a hair piece.

 

[jamesbooker1975]

Too bad there are no topicals nearly as effective as oral finasteride, and the topicals that do show promise go systemic anyways. If you forego oral finasteride in favor of a topical route, your topical route may soon be a hair piece.

Did you checked the Breezula compare to minoxidil of phase 2 ? The results at 6 month are almost the same. I must differ with you, this are all the drugs with enought studies that show that are not going systemic ( or are in a very low % like minoxidil ) :
Ketoconazole
Minoxidil
Tretinoina
17-Alpha estradiol ( also, I am not 100 % sure about this and systemic )
Espironolactone .

If minoxidil don't worked for you, search about minoxidil sulphate.
Crossing finger, I will go only topical soon. I think that pass from blocking almost 100 % of DTH to not blocking at all ( systemic way ) will put all the hormone balance even more crazy.