.25mg finasteride...what % dht inhibited?

ugh

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As the thread's title says, how much dht is reduced when using .25mg per day?
 

pratc

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Not exactly an answer to your question but along the right lines.

It has been posted on this forum that 1mg/d (the usual dose) is 83% as effective as 5mg/d. Also, 0.2mg/d is 82% as effective as 1mg/d

The graph isn't linear but 0.25mg will be a bit more than 82%

btw a dose of 0.75 mg/d is about 95% as effective as 1mg/d
 

ugh

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Your talking about finasteride right? not dutasteride? So .25mg (1/4) of a 1mg pill inhibits 82% of what a 1mg dose would?
 

pratc

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Yes, finistrade. 0.25mg/d should be about say 85% as effective as the normal 1mg dose. I've not read the studies but maybe % 'effective' is equivalent to reduction of DHT amount. The graph seems to level out as dosage (x axis) is increased so it is like diminishing returns for larger doses and conversely the change in effectiveness is greater for inccremental smaller doses (below about 1mg).
 

shyguy

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just remember that finasteride has a cummulative effect in the body... that means it continues to build in the blood after continuous usage... with that said, .25mg ed or possibly every other day will be of benefit and have a good dht effect... I necesarily believe that you dont have to destroy all dht in the body which when doing that gives the unpleasant side effects... I think you just need to reduce dht levels enough back to tolerable dht levels that the body can handle without inducing hairloss.....
 

MPBWarrior

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i thought 0.5mg had approximately 80% effectiveness as 1mg and then 0.25 had 80% effectiveness as 0.5mg, not 0.25mg having 80% effectiveness as 1mg.
 

pratc

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The information I gave was from a printout I made from a posting that I thought was from this forum. I can't verify teh data or say who the author was but it gave those details and also information from a proscar vs dutasteride study.
 

blakes30

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Where is that printout showing the different levels of effectiveness at varying doses?
 

blakes30

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MPBWarrior said:
i thought 0.5mg had approximately 80% effectiveness as 1mg and then 0.25 had 80% effectiveness as 0.5mg, not 0.25mg having 80% effectiveness as 1mg.

where did you hear that 0.5mg was 80% as effective?
 

MPBWarrior

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can't remember. i thought that was the common knowledge. someone who knows give us a hand on this!
 

ANDREW_J_I

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hmmm, im really thinking bout going a different route instead of 1mg a day. i may do 1mg every other day or 0.5mg a day, which du reckon?? coz dnt it have a half life etc...
 

blakes30

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well, according to the FDA studies,

0.2mg is just as effective as 1mg!!!!!!!!!

http://www.physics.upenn.edu/facultyinf ... index.html

"As seen in Fig. 1, reproduced from the FDA material, the percent change of DHT for placebo and .01 mg finasteride were identical and essentially zero within a reasonable statistical estimate. The change dropped by 60 % for a .05 mg dose and stayed that way for all dosages up to 5 mg. Thus a 20 times smaller dose than PROPECIA had the same effect on the DHT. "

"The data supplied to the FDA on ``efficacy parameters'', (NDA 20-788, table 8.1.2.4.2) compared .2 and 1.0 mg dosages in hair count, investigator assessment, and global photographic assessment but did not present data for other dosages above .02 mg. However the sample of participants (100) was small and the differences between the .2 and 1.0 dosages in the first two cases were not apparent and, in the photographic assessment, which showed a larger mean improvement for 1 mg, the values overlapped statistically at the 95% confidence level"
 

ANDREW_J_I

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^holy sh*t!! is that real? thats one great study for people who gets sides or want to save money. im experiencing sum sort of side effect :(.
 

ANDREW_J_I

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^blakes, u seem to be finding very relevant information. have u come across any studies to do with propecia and fertility ATALL????
 

blakes30

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no---i haven't seen any studies on fertility---that was an issue i worried about too

however, i can tell you that after over 8 years of taking propecia, i got my wife pregnant within 1 month of her coming off the pill, and we have a healthy baby boy!!!! :lol:
 
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