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Been on Finasteride for over a year, is it worthwhile adding some topical spironolactone, or is it a waste of time. Anyone using both and had an improvement?
Adding Topical spironolactone to Finasteride
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LookingForAnswers
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Yes, separately. I take the finasteride orally and would like to add an application of spironolactone between my minoxidil applications. I have a stubborn spot on my crown and need to try adding something else, was also thinking of flutamide but not sure how safe they are. What do you think? Also was thinking of maybe Proxiphen.
Cassin
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I have actually been thinking of using spironolactone a few times a week myself but I have held off. Instead I upped my Copper Peptide use and am being more consistent with my nizoral.
The reason I did this over spironolactone is because I am familiar with both products since I have used them so much and I am trying to keep my costs down. Its nothing against Sprio whatsoever.
Anyway...I am sure there quite a few people who have done this...you just might have to bump the thread a few times.
The reason I did this over spironolactone is because I am familiar with both products since I have used them so much and I am trying to keep my costs down. Its nothing against Sprio whatsoever.
Anyway...I am sure there quite a few people who have done this...you just might have to bump the thread a few times.
SoThatsLife
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I have read several places that the Sprio cream is better than liquid. spironolactone cream is 5% and liquid is 2% to. Another thing is the smell, but the cream is supposed to not have a heavy oder, only if you work out and start to sweat and get hot, then something reacts and the spironolactone could start to smell.
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Bryan said:
Bryan....
Why do you not feel that it could boost my chances of additional growth, by suppressing the androgen receptors in this area shouldn't it allow minoxidil a better chance of coaxing more growth from the vellus hairs? If not what would you suggest.
BTW...I spoke to Dr. Proctor today about Proxiphen and he said it might be worthwhile to add it to my current regimen since it contained among other ingredients, spironolactone, that would additionally suppress the androgen receptors in that area, was he wrong? I do not want to waste my time adding another topical.
Currently using 1mg Finasteride and twice daily 5% Rogaine Liquid. What more can I add to accomplish this?
Add Nizoral 1%. Cheap and so easy. Add a shampoo with Piroctone Olamine for your Nizoral off days. That still leaves up to 3 days per week for any other shampoo.
Bryan means that spironolactone won't give super regrowth. Androgen receptor blockers just let you maintain. Castration just stops hairloss.
However, I think 5 alpha reductase inhibitors may have better regrowth potential. I suspect, and this is not backed up by doctors, that the extra testosterone that is not turned into DHT and is turned partially into estrogen, may reverse hair loss. I think extrogen might be able to reverse it some. But don't trust me on that. That is just my unproven guess. I base that guess on the fact that Dutasteride 2.5mg regrew so much more hair than 0.5mg, and more than Propecia or Proscar ever regrew by 1 year, even at the 6 month point. Bryan believes this is just from there being less DHT spillage from the 5ar1, but I think it is from all the extra testosterone left behind from blocked 5ar1, which then aromatizes into estrogen.
OK, I've taken this way off topic for a possibly wrong theory. Just saying if you can inhibit 5ar1 topically, you may get great results, whether my view or Bryans is right. Not sure how great is great though, since they cut the study off after 9 months.
So you got growth stimulant: minoxidil
Androgen receptor blocker: spironolactone
5ar2 blocker: propecia
5ar1 blocker: some other unproven on humans topical
Nizoral: weak androgen receptor blocker, possible weak 5ar1 blocker, to easy and cheap not to use. Nizoral is also a growth stimulant that is synergistic to Minoxidil.
Don't add extrogen to your head: it goes systemic.
Don't take dutasteride 2.5mg: it can have side effects on your body. Bad side effects that last years once it builds up.
Proxiphen: 60mL is supposed to last 2 months, I think. I could be off. It is $100, vs $40 or so for spironolactone 5%. You already have minoxidil in your regimine. Bryan has said Proxiphen is about 2% minoxidil, 2% spironolactone, and has 10 other ingredients Proctor has patents on. I don't know how good they are, or if one of them is used by some hospitals. Read up on it. If those ingredients actually work, I'd say Proxiphen is a deal. But I don't know. Bothers me we have to take his word on it since he is not published, and I don't know how to find peer critiques of studies anyway. He made it into lifeextension's book though. Maybe that counts as a peer review.
Bryan means that spironolactone won't give super regrowth. Androgen receptor blockers just let you maintain. Castration just stops hairloss.
However, I think 5 alpha reductase inhibitors may have better regrowth potential. I suspect, and this is not backed up by doctors, that the extra testosterone that is not turned into DHT and is turned partially into estrogen, may reverse hair loss. I think extrogen might be able to reverse it some. But don't trust me on that. That is just my unproven guess. I base that guess on the fact that Dutasteride 2.5mg regrew so much more hair than 0.5mg, and more than Propecia or Proscar ever regrew by 1 year, even at the 6 month point. Bryan believes this is just from there being less DHT spillage from the 5ar1, but I think it is from all the extra testosterone left behind from blocked 5ar1, which then aromatizes into estrogen.
OK, I've taken this way off topic for a possibly wrong theory. Just saying if you can inhibit 5ar1 topically, you may get great results, whether my view or Bryans is right. Not sure how great is great though, since they cut the study off after 9 months.
So you got growth stimulant: minoxidil
Androgen receptor blocker: spironolactone
5ar2 blocker: propecia
5ar1 blocker: some other unproven on humans topical
Nizoral: weak androgen receptor blocker, possible weak 5ar1 blocker, to easy and cheap not to use. Nizoral is also a growth stimulant that is synergistic to Minoxidil.
Don't add extrogen to your head: it goes systemic.
Don't take dutasteride 2.5mg: it can have side effects on your body. Bad side effects that last years once it builds up.
Proxiphen: 60mL is supposed to last 2 months, I think. I could be off. It is $100, vs $40 or so for spironolactone 5%. You already have minoxidil in your regimine. Bryan has said Proxiphen is about 2% minoxidil, 2% spironolactone, and has 10 other ingredients Proctor has patents on. I don't know how good they are, or if one of them is used by some hospitals. Read up on it. If those ingredients actually work, I'd say Proxiphen is a deal. But I don't know. Bothers me we have to take his word on it since he is not published, and I don't know how to find peer critiques of studies anyway. He made it into lifeextension's book though. Maybe that counts as a peer review.
