Cassiopeia Release Full Year Results To 2018 Including Update On Breezula

[ScaredOfBalding]

this is very bad news. most people perceive CB to be a lot weaker than RU also RU is non steroidal which in theory should make it more effective as well. if even with RU most people have had mediocre results.. I don't know. here is my prediction: CB works really well in a short period of time for example after 6 months people get decent regrowth. however unlike with finasteride the efficiency will fade off a lot quicker so we won't see something like can average maintenance of 7 years as with finasteride. it will probably work really well in short term. probably because of the different way of action. the other guy already reported he had maintenance with RU but it faded after 3 years.

remember with finasteride, you reach your MAXIMUM of regrowth and efficiency you can achieve on average after 1.5-2 years. thats how long it takes for it to really kick in. I'm afraid they won't even do a 5 year study with CB as they did with finasteride so we have a product that we know can generate short term growth but what about down the line?

how can it be this hard to create a safe efficient anti androgen, holy sh*t.

I don't see any reason as to why CB would lose efficacy quicker than finasteride. Not in the mechanism of action and not in the results.

 

[alibaba92]

me neither but I have a bad feeling about everything these days when it comes to hairloss research. and thats pretty much the only way CB can disappoint at this point. the way I thought is receptors get more sensitive when there is a lack of androgens but that would defeat the entire point of androgen deprivation therapy in prostate cancer and even in finasteride usage so I guess it won't play a major factor

Just wait for 1 year result. Worst case is to take finasteride and use cb. Attack this sh*t from multiple angle

 

[kungfukenny]

I was using RU. I'll just out in my two cents.

RU wasn't released. No one knows why. We can all simply speculate.

One thing was some poster saying RU effected his heart and he was going to die. Was a big post. I know it personally scared the sh*t out of me. RU also does go systemic and essentially would have all the sides of finasteride.

You can get RU now... But CB has been proven to be safe. And if you can get it you're only losing out on money.

I'll take spending more knowing I'm safe over risking my health.

Also not sure why people are debating if CB works. It's proven to work 2x finasteride.

So all we have beyond speculation are these facts.

CB is twice as strong as finasteride.
CB has a safe profile.
CB is expensive.
RUs safety profile is ???
RU is a really strong anti androgen.
RU was discontinued for ???

To me. RU is a big risk. I did it for a year. I'm ok. But after reading about that guy I'd rather go with something I know than something I don't.

I know the sides of finasteride.
I know the safety of CB.
I don't know anyone of this with RU.

Yeah I tried RU last summer and literally after first use it gave me chest pains, scared the sh*t out of me so stopped. Maybe I’m just allergic to the carrier or something but the chest pain was definitely too significant to continue using it.

 

[Phatalis]

Woah woah woah woah.

Guys calm the f*** down haha!

I was very lackadaisical about how I used RU. Admittedly.

So take what I said with a grain of salt. I do think I maintained on it.

I was regular with it. I used an average recommend dosage. I don't remember TBH. I followed hellousers guide.

But I was lackadaisical in when I took it and I mixed it quickly... I did measurement it out etc but it wasn't as... focused? As I would now. My hairloss wasn't so bad.

Vehicle was pg and ethanol.
Yeah nw2. So I wasn't super focused on regrowth.
Didn't even test.

So yeah I'm a big dumb sh*t and ignore my comments haha.

With that said we don't truly know the reasoning behind hairloss and we don't truly know why or how certain medications lose effectiveness over time


So no reason to stress about it.

We DO know stress has massive effects on the human body... And could exacerbate hairloss haha.

So chill out and do your best

 

[Pephair]

Hi guys, I'm actually working on a formulation for CB. As soon as I get all the ingredients and test it out, I should be able to get everyone some of the necessary ingredients to prepare the delivery vehicle.

Please note, you still will have to source the active yourself. I will get you all the other ingredients to make sure your topical CB works as well as the Phase 2 studies.

Fagron has recently launched a large range of vehicles for scalp application of actives. They're calling the range Fagron TrichoConcept.

The ones I'm testing are TrichoOil and TrichoSol.
The TrichoOil is designed for lipophilic actives like CB, whereas TrichoSol is designed for more hydrophilic actives like Minoxidil.

I'm gonna see what the texture of TrichoOil is like and whether it leaves a greasy layer on the scalp or not. I'll keep you guys posted.

Once I've got more info, I can get everyone some

Any update?

 

[NotInmywatch]

what makes me optimistic is that winlevi obviously did not stop working after 6 months so we know that this angle of into androgenic action is kind of sound

this was the holy grail since the beggining, a topical androgen receptor blocker without ruining your body.
not even dutasteride can block 100% scalp DHT synthesis and besides that, testosterone by itself is binding the AR and killing your hair at 1/10 speed.
your scalp will become MtF transgender. if you start very early, david schimmer norwood 0 hairlines will become feasible.

 

[Ollie]

People need to stop comparing RU and CB. Yes RU might have a stronger binding affinity for the AR but im sure there are many more variables at play. The only people on this forum who have had any success with RU are 45-50 year olds barely have f*****g hairloss anyway. I went up to 7% with RU for over a year and if anything it slowed down some hair loss for me but thats it.

However, a lot of people who have tried CB have said they got regrowth, but at the time couldn't continue because how expensive it used to be. At one point before RU i was doing CB at just 50mg in 3ml of the study vehicle (transcutol: eth: pg) and was getting some regrowth along the hairline, but like others had to stop after 3 months cause of cost.

On a better note, as of next week im starting CB again. Cant afford 7.5% twice a day, and as 2.5% has the same results as 5% twice daily, i'll be doing 2.5% twice daily. I am on 0.25mg of finasteride which doesn't make me a great test subject, however 1mg of finasteride was getting me all my hair back, but when i dropped to 0.25mg from sides i lost much of my growth in a couple of months and now continue to lose hair, so if this gets me some regrowth it should be a decent testimony.

 

[Pephair]

So is the general consensus that we can just apply a larger amount of Winlevi on the scalp for regrowth? And the mechanism would work identically? /broscience

 

[ScaredOfBalding]

So is the general consensus that we can just apply a larger amount of Winlevi on the scalp for regrowth? And the mechanism would work identically? /broscience

Nope. Won't work aswell.

 

[Btg]

winlevi has a vehicle not suited for scalp absorption so i wouldnt count on it

 

[AndrewU]

winlevi has a vehicle not suited for scalp absorption so i wouldnt count on it

Would dermapen not enhance the absorption?

 

[AndrewU]

Also what’s the potential cost of Breezula?

 

[Ollie]

Would dermapen not enhance the absorption?

Doesn’t matter you’d need a prescription for it and you’d get a small tube a month most likely

 

[Pephair]

Doesn’t matter you’d need a prescription for it and you’d get a small tube a month most likely

I have a little bit of acne, we can make this work boys!

 

[alibaba92]

However, a lot of people who have tried CB have said they got regrowth, but at the time couldn't continue because how expensive it used to be. At one point before RU i was doing CB at just 50mg in 3ml of the study vehicle (transcutol: eth: pg) and was getting some regrowth along the hairline, but like others had to stop after 3 months cause of cost.

Good to hear that, are they from private forum ?

Cause there is one mega thread in baldtruthtaIk on CB and none had regrowth.

 

[Seuxin]

Anyone got full study?

 

[Ollie]

Good to hear that, are they from private forum ?

Cause there is one mega thread in baldtruthtaIk on CB and none had regrowth.

Several people from a few places. Here, and discord, but I don’t know anyone on the private forum.

I don’t recall anyone trying CB on there recently . They tried it a couple of years ago when the price was over $100 a gram . Anyone who was running it I remember was doing stuff like 1.5% once a day. 2.5% twice a day is minimally required for what looks comparable to minoxidil type results (average responder) . 7.5% twice a day is what’s needed .

 

[Ollie]

i don't recall a single person claiming regrowth on cb but some on ru

CB has less people who have tried it, but those who I know who have tried it all have had regrowth but had to stop cause of cost.

I use to run 400mg of RU a day at one point and it did nothing at all. I don’t know anyone who has said anything good about RU other than it ‘maintains’ which is inadequate because they might have kept the hair without it.

 

[Ollie]

i just dort know of anyone who got regrowth on cb

Who do you know who has had regrowth on RU ?

I’ve been on the forum for a little while but lurked for a couple years prior to joining and every testimony of RU has either been it does nothing, or I think my RU is fake because it also does nothing.

 

[Makaveli1988]

CB has less people who have tried it, but those who I know who have tried it all have had regrowth but had to stop cause of cost.

I use to run 400mg of RU a day at one point and it did nothing at all. I don’t know anyone who has said anything good about RU other than it ‘maintains’ which is inadequate because they might have kept the hair without it.

Did u have any sides from ru?