Day 2 On Finasteride - Sensitive Nipples Help Scared And Worried

Feelsbadman

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Yes it does, if you look at the finasteride response curve, it inhibits dht but not as much as 1 mg.

Thank you,also do you know how long till finasteride is completely out of ur system?

i dont understand how i got such bad sides so quickly?
my penis feels so weird/soft and bends hugely to the left. before it was jsut a small bend i assume this is because before i could get rock hard so it would straighten more, now it's soft and more bendy
 

JohnSmith21

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Here's another poll from a couple of years ago with 500+ participants from a foreign hairloss forum. http://www.haarweb.nl/forum/showthread.php?t=2848

Guess, the results?

55%+ had side effects.

Stop coping, we know you're invested in the pill you swallow daily. And we know Merck lied about their studies, was a big article about it last year:
A REUTERS SERIES

Court let Merck hide secrets about a popular drug’s risks

Lawsuits claim baldness drug Propecia causes sexual problems and depression. The judge sealed evidence – uncovered by Reuters – suggesting the maker downplayed the side effects. A widow wants the truth out.

Also not the first time Merck lied, look up Vioxx.

Anyway, sorry to say, the pill you see as your ultimate salvation for your hairloss is not safe, that's a fact.

Now let's wait for the weak insults and cope.
you know these polls are from people on a forum, and not the general population on finasteride you moron? millions of men take finasteride, and probably way less than 1% of them are on this site. and people with no sides or problems don’t go on forums. are you too stupid to understand this
 

RealSnickers

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Thank you,also do you know how long till finasteride is completely out of ur system?

i dont understand how i got such bad sides so quickly?
my penis feels so weird/soft and bends hugely to the left. before it was jsut a small bend i assume this is because before i could get rock hard so it would straighten more, now it's soft and more bendy
It doesn't sound like this drug is for you. Not because it isn't working, but because you are making yourself believe you have sides. It's not possible to develop anything from this drug in that time frame. You should quit taking it now and try something else for your hair.
If you freak out like this for sensitive nipples and blame finasteride right away, you will probably blame everything and anything that happens to you on finasteride down the road and maybe worse, you will convince yourself you have post-finasteride syndrome.
I really don't mean to be rude or anything, just an honest opinion with good intentions for you.
 

FilthyFrancis

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..... Its sad that you are letting yourself go bald over neurotic fears from a imaginary syndrome.

How can you make such claim when even Merck backed out on this, updating their leaflet with permanent ED risks. This is pure misinformation.

The discussion shouldn't be around whether PFS is real or not, but rather about the odds of suffering from this rare syndrome when taking finasteride. If the treatment is still on the market, it means health authorities consider Finasteride to offer a positive risk/benefit ratio. I am not saying these entities are wrong.

In the end, it's a personal choice that needs to be taken by each and everyone of us. The more misinformation, the more difficult it gets to have a clear understanding of what is at stakes.
 

FilthyFrancis

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If anything useful could be done by one person, it would be to start an extensive thread with pros and cons of Finasteride, highlighting both the positive findings and the negative studies.

This war, taking over each single thread about Finasteride, is leading us nowhere. It only generates more frustration on both sides, perhaps generating stress and making you shed? ;)
 

Derelict

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Probably an indicator oncoming gyno, weird it happened so quickly but if you want your save your hair you will either need to deal with sides like that or go bald, maybe try RU or CB
 

JohnSmith21

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Oh look more cope. Lol at "people with no sides or problems don't go on forums", you really are an idiot. This is a hairloss forum not propeciahelp. A forum unrelated to fina or side effects still gives us poll results of 50% experiencing side effects, that says it all. Btw, it's not only this forum.

Let's look at an older poll on a different hairloss forum.

http://www.haarweb.nl/forum/showthread.php?t=2848

A poll of 500+ people, guess how many experienced side effects? 55%.

You're on long term hormonal treatment to save your ratsnest. You really think blocking 70% of an important male hormone doesn't create any side effects besides saving your hair? LMFAO! You desperate, naive sucker.

And here are some more studies:

Adverse Event Reporting in Clinical Trials of Finasteride for Androgenic Alopecia: A Meta-analysis.

CONCLUSIONS AND RELEVANCE:

Available toxicity information from clinical trials of finasteride in men with Androgenetic Alopecia is very limited, is of poor quality, and seems to be systematically biased. In a cohort of men prescribed finasteride for routine treatment of Androgenetic Alopecia, most would have been excluded from the pivotal studies that supported US Food and Drug Administration approval for Androgenetic Alopecia. Published reports of clinical trials provide insufficient information to establish the safety profile for finasteride in the treatment of Androgenetic Alopecia.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064044/


a substantial body of evidence exists which points to serious and potentially ill-health effects of 5?-RIs' therapy. These include loss or reduced libido, erectile dysfunction, orgasmic and ejaculatory dysfunction (Table 2) [99], development of high grade PCa tumors (Fig. 4), potential negative cardiovascular events, and depression. The side effects are potentially harmful in some individuals and in young men may be persistent or irreversible [100]. The argument that the benefits of these drugs outweighs the risks is slowly eroding in the face of new emerging scientific evidence from preclinical (Figs. 2, ?,3;3; Table 1) and clinical studies (Table 2). The available data demonstrate that such drugs do pose serious adverse effects, especially in a subset of men who may have the predisposition to be affected severely. This is also corroborated by the overwhelming FDA disapproval of these drugs for the chemoprevention of PCa. The FDA mandated relabeling issued in 2011 equally points to the dark side of these drugs on human health.

The occurrence of persistent adverse sexual, physical, neurological, and psychiatric side effects after 5?-reductase inhibitor is well supported by the existing data.

https://link.springer.com/article/10...930-018-0163-4

Patients treated for male pattern hair with finasteride show, after discontinuation of the drug, altered levels of neuroactive steroids in cerebrospinal fluid and plasma.

Abstract

Observations performed in a subset of patients treated for male pattern hair loss indicate that persistent sexual side effects as well as anxious/depressive symptomatology have been reported even after discontinuation of finasteride treatment. Due to the capability of finasteride to block the metabolism of progesterone (PROG) and/or testosterone (T) we have evaluated, by liquid chromatography-tandem mass spectrometry, the levels of several neuroactive steroids in paired plasma and cerebrospinal fluid (CSF) samples obtained from post-finasteride patients and in healthy controls. At the examination, post-finasteride patients reported muscular stiffness, cramps, tremors and chronic fatigue in the absence of clinical evidence of any muscular disorder or strength reduction. Although severity of the anxious/depressive symptoms was quite variable in their frequency, overall all the subjects had a fairly complex and constant neuropsychiatric pattern. Assessment of neuroactive steroid levels in CSF showed a decrease of PROG and its metabolites, dihydroprogesterone (DHP) and tetrahydroprogesterone (THP), associated with an increase of its precursor pregnenolone (PREG). Altered levels were also observed for T and its metabolites. Thus, a significant decrease of dihydrotestosterone (DHT) associated with an increase of T as well as of 3?-diol was detected. Changes in neuroactive steroid levels also occurred in plasma. An increase of PREG, T, 3?-diol, 3?-diol and 17?-estradiol was associated with decreased levels of DHP and THP. The present observations show that altered levels of neuroactive steroids, associated with depression symptoms, are present in androgenic alopecia patients even after discontinuation of the finasteride treatment. This article is part of a Special Issue entitled 'Sex steroids and brain disorders'.


https://www.ncbi.nlm.nih.gov/pubmed/24717976

The Dark Side of 5?-Reductase Inhibitors' Therapy: Sexual Dysfunction, High Gleason Grade Prostate Cancer and Depression

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064044/


With aging, abnormal benign growth of the prostate results in benign prostate hyperplasia (BPH) with concomitant lower urinary tract symptoms (LUTS). Because the prostate is an androgen target tissue, and transforms testosterone into 5?-dihydrotestosterone (5?-DHT), a potent androgen, via 5?-reductase (5?-R) activity, inhibiting this key metabolic reaction was identified as a target for drug development to treat symptoms of BPH. Two drugs, namely finasteride and dutasteride were developed as specific 5?-reductase inhibitors (5?-RIs) and were approved by the U.S. Food and Drug Administration for the treatment of BPH symptoms. These agents have proven useful in the reducing urinary retention and minimizing surgical intervention in patients with BPH symptoms and considerable literature exists describing the benefits of these agents. In this review we highlight the adverse side effects of 5?-RIs on sexual function, high grade prostate cancer incidence, central nervous system function and on depression. 5?-Rs isoforms (types 1-3) are widely distributed in many tissues including the central nervous system and inhibition of these enzymes results in blockade of synthesis of several key hormones and neuro-active steroids leading to a host of adverse effects, including loss of or reduced libido, erectile dysfunction, orgasmic dysfunction, increased high Gleason grade prostate cancer, observed heart failure and cardiovascular events in clinical trials, and depression. Considerable evidence exists from preclinical and clinical studies, which point to significant and serious adverse effects of 5?-RIs, finasteride and dutasteride, on sexual health, vascular health, psychological health and the overall quality of life. Physicians need to be aware of such potential adverse effects and communicate such information to their patients prior to commencing 5?-RIs therapy.

Keep on coping and don't forget to take your daily tranny pills. You will learn.
okay so what percent of people who take finasteride do you think has an account on this website? forreal? obviously less than one percent. 99% of people who take finasteride, take the pill and continue their life, not create a forum and talk about it. wtf are you even talking about anyway? the treatments have been the same for 20 years dumb f***. you either take finasteride or you don’t lol. that’s it. what else is there to talk about. take it, stop losing hair, don’t take it, keep losing hair. so we can all delete our accounts now! that’s all there is to it buddy. so the fact that u think these polls represent the entire population is literally retarded. like i said, less than 1% of finasteride users are on the site , and it’s the crazy hypochondriacs .... google sample bias
 

sonictemples

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It doesn’t directly. Controlling aromatase while using 5AR inhibitors is a must imo
 

whatevr

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One year of Finasteride has left me with gyno lumps that I will probably have to get surgery for sometime soon. Nothing too terrible, but there's a "mound" there when it should be flat. I've been avoiding the issue for the past 4 years but I think I should just get it done with so I don't have to be self-conscious of whether it's visible or not when wearing tight fitting shirts. Tried raloxifene, tamoxifene, and letro, didn't really do much after the fact.

I've had people tell me during the time that the puffy nipples would go away if I quit Finasteride - that wasn't the case. The burning and nipple sensitivity started within the first two weeks of taking it, but of course I was desperate to keep my hair and kept taking it for the entire year. My results with hair would've probably been even worse had I taken an AI with it.

Anyway, I've always had normal estrogen levels and my T was >1000 last time I checked, so I guess that makes me a girly-boy, whatever the f*** that means.
 

Feelsbadman

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One year of Finasteride has left me with gyno lumps that I will probably have to get surgery for sometime soon. Nothing too terrible, but there's a "mound" there when it should be flat. I've been avoiding the issue for the past 4 years but I think I should just get it done with so I don't have to be self-conscious of whether it's visible or not when wearing tight fitting shirts. Tried raloxifene, tamoxifene, and letro, didn't really do much after the fact.

I've had people tell me during the time that the puffy nipples would go away if I quit Finasteride - that wasn't the case. The burning and nipple sensitivity started within the first two weeks of taking it, but of course I was desperate to keep my hair and kept taking it for the entire year. My results with hair would've probably been even worse had I taken an AI with it.

Anyway, I've always had normal estrogen levels and my T was >1000 last time I checked, so I guess that makes me a girly-boy, whatever the f*** that means.

i reduced my dosage to 0.25mg and my nipple sensitivty went away so idnt know what t do now dont know if its working or not with my hair :/
 

INT

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i reduced my dosage to 0.25mg and my nipple sensitivty went away so idnt know what t do now dont know if its working or not with my hair :/

How many days after you reduced the dosage did the sensitivity go away?
 

Feelsbadman

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How many days after you reduced the dosage did the sensitivity go away?

about 2 weeks

got a question, i just wonder, someone who has low androgens maybe they can get away with taking a smaller dose of finasteride? whereas someone who has rela high test/high dht will need 1mg a day etc?
i think i have low andrgens/low t etc
 

JohnSmith21

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che
Hahaha, holy fck the cope is immense with this hopeless balding naive mongoloid.

"99% of people who take fina continue their life" That's pure conjecture you made up in your mind idiot. And you have more treatments than just fina you utter retard. Delete your account, your cope is embarassing..

Answer this: Do you really think a long term hormone treatment that blocks DHT for 70% and affects many functions in the body will ONLY affect your fckin hair? Are you this naive? Have you brainwashed yourself so hard to believe it's "safe"? Cognitive dissonance is strong with you.

Lol but continue taking your tranny dugs, you will learn the hard way.


Finasteride, sold under the brand names Proscar and Propecia among others, is a medication used mainly to treat an enlarged prostate or hair loss in men.[2] It can also be used to treat excessive hair growth in women and as a part of hormone therapy for transgender women.[3][4] It is taken by mouth.[2]


https://en.wikipedia.org/wiki/Finasteride
check my page, i’m Norwood 1 with no sides from finasteride so smd
 

Derelict

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One year of Finasteride has left me with gyno lumps that I will probably have to get surgery for sometime soon. Nothing too terrible, but there's a "mound" there when it should be flat. I've been avoiding the issue for the past 4 years but I think I should just get it done with so I don't have to be self-conscious of whether it's visible or not when wearing tight fitting shirts. Tried raloxifene, tamoxifene, and letro, didn't really do much after the fact.

I've had people tell me during the time that the puffy nipples would go away if I quit Finasteride - that wasn't the case. The burning and nipple sensitivity started within the first two weeks of taking it, but of course I was desperate to keep my hair and kept taking it for the entire year. My results with hair would've probably been even worse had I taken an AI with it.

Anyway, I've always had normal estrogen levels and my T was >1000 last time I checked, so I guess that makes me a girly-boy, whatever the f*** that means.

Did your hair recover from the letrozole shed?or did you not experience a shed? letro absolutely decimated my crown in the 2 months i was on it, 2.5mg a day. I stopped it maybe just over 2 months ago and my crown still doesn't look like it's recovering.
 

whatevr

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Did your hair recover from the letrozole shed?or did you not experience a shed? letro absolutely decimated my crown in the 2 months i was on it, 2.5mg a day. I stopped it maybe just over 2 months ago and my crown still doesn't look like it's recovering.

For the most part, yes, took a few months though. I only went up to 1.25 mg however, at 2.5 mg I can only imagine the devastation.
 

Mr. Prince

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A month late, but I did have sensitive nipples in the first few days of finasteride. I think it was 3 or 4 days, can't remember exactly. I'm now 3 years on finasteride and I never experienced that feeling ever again. Right now my only side effect of finasteride is watery semen and my semen also lost its bleach smell. it's now odorless and honestly this is probably the most worrying side effect so far for me.
 

JohnSmith21

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Good for you tranny, how long are taking that poison? Most get sides after some time so keep on swallowing those daily hormone pills.
i’m 185lbs, bench 315, mad facial hair. no sides. your just a beta fear monger who losing hair
 
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