DHT-blocking Topicals (Please submit information)

Bryan

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collegechemistrystudent said:
I must point out that here linoleic acid out performed ALA, whereas in the PubMed abstracts you posted, ALA outperformed linoleic acid.

Hahahah! I wondered if you were going to notice that! :)

The list I compiled before wasn't just based on this one hamster study, it was sort of the "average" of some other studies, too, which I have here. That list is still my best overall estimate of the relative potencies of those common fatty acids.

collegechemistrystudent said:
Since RU costs 10x as much as spironolactone for the same dose, I'm tempted to go with the spironolactone.

spironolactone would appear to be more cost-effective than RU, but nevertheless there's still that troubling little issue of whether or not the MAXIMUM POSSIBLE effect of topical spironolactone will always be less than what you can get with topical RU.

Bryan
 

MPBWarrior

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Right, so spironolactone seems to be the best choice then... at least for us who don´t know enough about mixing oils to make solutions and the like...

Which spironolactone is the most recommended? I heard something about the cream being the best choice, is this correct?

Thanks
 

CCS

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MPBwarrior, buy the 5% cream.


Anyway, I'm wondering if fatty acids mixed with ppg and ethanol can serve as a cream for the spironolactone (2 in 1), or if it is better to but both in the dermavan. I'd rather do the former.


As for spironolactone vs RU, I know it is important to start as early as possible whatever I do. The RU would tell me what I'm capable of growing. And if my smooth forhead area does not grow hair in a year, I know the spironolactone will take care of the rest of my head just fine. Or rather, if proxiphen, dutasteride, GLA, RU, NANO shampoo, Minoxidil 5%, and arginine don't grow hair out of my slick scalp, then probably nothing will.


Felk, Revivogen also has oligomers, which i think are from apples, but i'm not sure. There was a japanese study on it.
 

Bryan

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collegechemistrystudent said:
i don't know now to separate all the filler from spironolactone cream. water will take care of the lactose, but there is a lot of other stuff that is not water soluble, and a lot of ethanol is required to dissolve spironolactone, more than i would want in the cream for that dose of spironolactone.

Personally, I don't worry too much about the fillers in spironolactone tablets. For all we know, they may actually be slightly beneficial, by helping to slow-down the absorption of the spironolactone a little.

Bryan
 

CCS

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Do 25mg tablets have a higher ratio of filler to spironolactone than the 100mg tablets?
 

Bryan

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collegechemistrystudent said:
Do 25mg tablets have a higher ratio of filler to spironolactone than the 100mg tablets?

I've only used 100 mg spironolactone tablets, so I haven't had the opportunity to weigh any 25 mg ones. My hunch is that they also weigh 500 mg, in which case they'd obviously have a higher ratio of filler to spironolactone.

BTW, College, you posted something recently, speculating about the degree to which fatty acids bind to androgen receptors, and how it compares to testosterone and DHT. I was wanting to reply to that, but I didn't have enough time when I first saw it. Now I can't find that damned post of yours! :-x Can you point me to it again?

Bryan
 

CCS

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CCS

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I just want to add that only the Revivogen vials are a deal. If the shampoo has much fatty acid in it, you could not rinse it off with water. Maybe it has emulsifiers that take care of this. I don't know how that would effect absorption.
 

MPBWarrior

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Between revivogen and dr lee´s 5% spironolactone cream, which one would u guys say was the best choice?

Thanks
 

CCS

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i think they will be equally effective from different angles and you should use both if you want maximum effects.
 

MPBWarrior

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And what about between spironolactone, Revivogen and Pro-x?
 

CCS

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all three act in completely different ways. Add minoxidil and you got a little bit of everything.
 

MPBWarrior

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My only problem with minoxidil is that it doesn´t seem to do anything in the long-run for maintenance. but thanks for your help College. also, i´m probably only likely to add one of revivogen, prox-n and spironolactone cream at the moment. which one would u most recommend-basically, my problem is a receding hairline. Thanks
 

CCS

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I don't know. I don't any of those three will stop your hairloss by themself.
 

MPBWarrior

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what´s the naturalis topical?
 

CCS

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The only natural topical blockers are fatty acids ALA, GLA, oleic acid, linoleic acid, and one of the longer omega-3's, GLA being the strongest 5ar blocker.

Beware of scams that claim saw palmetto works. It has a very weak effect only because of all oils, it has one of the highest percentage of free fatty acids. It is better to buy fatty acids that were removed from their glycerol in a factory. Revivogen is one such product. I prefer to buy the fatty acids from other sources.
 

MPBWarrior

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thanks college. i think my next addition to my regimen will be either spironolactone or prox-n!
 
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