DHT is a Factor; NOT THE CAUSE

freakout

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I Broke the Mystery of Male Pattern Baldness

idontwanttobebalding said:
How are men who do not suffer from male pattern baldness different than those of us who do? How do they handle the "mysteries" or do they not apply. Why is their scalp hair follicles unaffected? If genetics only play a minor role than what seperates us?
I posted this in another forum before I found Mercado's book.
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Like the flip side of a coin, if its not genetic, it has to be environmental. The word 'environment' has two types - internal and external. The two types are further classified into several types.

1. internal (biochemistry, biological, psychological, physiological, lifestyle, food, microbes)
2. external (psychosocial, lifestyle, physical, radiation, lifestyle)
3. the external environment CAN affect the internal environment.

CASE EXAMPLE on skin cancer given that fact that cancer is believed to have a genetic component:

1. external - prolonged sun exposure can cause increased risks to skin cancer.
2. internal - lack of green leafy vegetable in diet can cause increase risks to skin cancer.

CASE EXAMPLE on environmental changes:
1. Moderate amount of sun (primitive environment) can prevent certain diseases.
2. Absence of sun (modern environment) can cause certain diseases.
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Mercado does not seem to draw a line between internal and external environmental factors. This is understandable because the external can affect the internal in a contiguous manner.

To add to that, there is also a contiguous mechanism between genetics and environmental factors refered to as 'epigenetics'. You must have read this at Mercado's site.
 

freakout

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I Broke the Mystery of Male Pattern Baldness

As an epidemiologists, I think he's capable of gathering many of those data.
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This I gotta tell you because you seem to be the only one left who is vocal to possibilities beyond the androgenetic theory.

Everytime I read someone post the words 'scientific', specialy someone who didn't even know the word 'empirical' and who obviously doesn't know what 'inferential' nor 'false positives' means, I get struck with the strongest urge to puke.

The guy doesn't even know that a kid who says he has 100 lollipops is more believable than most "scientific" studies specialy when it come to medicine. :fun:
 

freakout

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I Broke the Mystery of Male Pattern Baldness

Thank you for being neutral. I'm not on the table because the debate is finished. It's my mistake for dragging Mercado's name; he has nothing to do with this forum.

I was just a card holder for the researchers of the mice experiment. This debate was between them and the 'experts' of androgenetic alopecia who, to be blunt, will still insist because it's their job to push it.

Sure they're going to say the experiment was never duplicated. But one can also say no one with credibility disputed it.

I can just imagine balding guys asking them for answers all these years and how they would feel once they find out the significance of the mouse who held the key since 2003.
 

freakout

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I Broke the Mystery of Male Pattern Baldness

In short: The belief of direct biochemical relationship between androgens and hair follicles (androgen sensitivity) ended in 2003.

The focus should now be on - to quote S Foote - the indirect relationship. 'Indirect' simply means there is a 'mystery' - an x factor which could be anything depending on each individual case.

It's up to anyone doing his own research to start from a fresh perspective on the true causation of the sensitivity of hair follicles. With lots of luck, I hope they find it or theirs. I think have mine.

The only objective for medical researchers is to find the most common causative factor. But with the heavy influence of pharmaceuticals on the research community, don't count on it.
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If you want to know why I speak in analogies and poker-like stand, I can post details of my email exchanges with Mercado.
 

Bryan

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Re: I Broke the Mystery of Male Pattern Baldness

freakout said:
In short: The belief of direct biochemical relationship between androgens and hair follicles (androgen sensitivity) ended in 2003.

LOL!! I don't know if even the authors of that mouse study themselves believe what you just said! :)

freakout said:
The focus should now be on - to quote S Foote - the indirect relationship. 'Indirect' simply means there is a 'mystery' - an x factor which could be anything depending on each individual case.

Do you know that even Stephen Foote admits (sheepishly) the accuracy of the in vitro studies showing that androgens suppress the growth of human scalp hair follicles, even though he claims (naively) that the sensitivity to androgens is supposedly caused by contact inhibition of those same follicles? :)
 

freakout

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I was actually referring to the S Foote of this forum. :)

I must admit that I haven't come across many of the references that you supposed 'experts' are talking about.

But that mouse makes about a hundred times more sense than "The Bryan Brain Cooling Assertion". :whistle:
 

Bryan

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freakout said:
I must admit that I haven't come across many of the references that you supposed 'experts' are talking about.

Don't you think a wise man would be careful to learn about the references being made by other people, before he plays guessing-games with other silly hairloss theories being posted on some other wacky site? :)

freakout said:
But that mouse makes about a hundred times more sense than "The Bryan Brain Cooling Assertion". :whistle:

Really? When you don't even seem to know for sure exactly what it is they're claiming in that "mouse study"? :smack:
 

freakout

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What the wacky site? Are you refering to this one
 

Bryan

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freakout said:
What the wacky site? Are you refering to this one

Yes. The one you like to play guessing-games about! :)
 

freakout

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Same here. I also thought the site was wacky! :)

You can just imagine the incredible claim "I Broke the Mystery of Male Pattern Baldness" Now, who in his right mind would make such an outragous claim! :jackit:

But what the heck I said to myself. Knowing how I hate meds and the really bad impression I have on pharmaceuticals and their dirty tricks, I decided to buy the book like I bought other wacky books.

What do you know - no one is selling used copies so I had to buy new. It's a good thing he made a lot of sense. I'd say about 500 times more sense than "The Bryan Brain Cooling Assertion". :whistle:

And that's how I found out that the 'androgen sensitivity' theory died :alien: a long time ago.
 

Bryan

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Yawn. Wake me up when you have something intelligent to say.
 

freakout

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I Broke the Mystery of Male Pattern Baldness

Hey wake up Bryan. I finally thought of something intelligent to say.

I told them that:

"Androgenetic Alopecia" stands for Suicidal Hair Follicles :)
 
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