Dr. Tsuji Kyocera, Riken Research, Organ Technologies Form Regenerative Hair Research Team

[jc3303]

I never said it wasn't going to work. I just said absolutely no other viable treatment has worked thus far and we've absolutely no reason to count on this working as all we have are promises made by companies that make money by making promises.

You think I'm not hopeful? Of course I am - it's just that I'm even more terrified we're not doing enough or certainly not everything we would be doing if we knew all these promising treatments would eventually fail. I'm scared we're being complacent.

I mean, fast forward 15 years to a hypothetical situation where every single one of these treatments turned out to be a bust. How do you reconcile yourself to not having fought harder just because you assumed things would turn out alright on their own? It's our lives that are at stake, of course I am not fine with a cure coming in 20 years' time. No one should be.

I never said I wasn't fighting, I hopped on finasteride as soon as my hair thinned noticeably. I would never sit around and wait on a technology unless it's a 100% chance it works.

The chance of all these methods failing is slim IMO, Tsuji has very solid science and tons of money and resources behind it. Histogen is also entering/already entered phase III, that's huge! It's been a very long time since that happened so things are slowly changing in the hair loss industry

 

[Torin]

Since there will be similarities between this technique and existing techniques, will a hair transplant doctor be needed for the placement to give the best aesthetic appearance possible?

Could something like a crown swirl pattern be recreated with these germ primordiums?

 

[Torin]

What similarities? Removing a patch of donor hairs? The germ hairs are INJECTED into the scalp, they're not even full follicles at that stage. How the hell would a surgeon help? They're going to grow as any follicle does during development - I'm sure certain injection techniques will enhance or inhibit growth, but I don't see how you transplant doctors would help considering the follicle isn't developed at that point.

I think they are going to engraft them much like current transplants, utilizing the fut method. So a surgeon experienced in placing grafts correctly is surely going to be pivotal.

 

[yellowbluegrey]

And yet most hair loss treatments that failed thus far were products of hard scientific work too.



A possible replacement hasn't stopped anyone's hair loss yet, much less regrown as much as we'll need regrown by the time it's out.
But yes, a finasteride replacement would have been a god sent 3 years ago, obviously.

I get nauseaous every time I realize balding guys just latch onto any fantasy that gets them through the day. That's what we're doing, really, isn't it? We're looking for excuses for companies and scientists when they don't even bother half as much themselves. We convince ourselves their products will work and will come in time yet they never ever do. But it doesn't matter because by the time they fall through, a promising new treatment is on the horizon so we cling to that and it's the same thing all over again. Rinse and repeat.

And I suspect many are even okay with that because it's more comfortable than actually getting up and doing something about this defect and society's investment. This isn't living, it's just getting by on false hopes and illusions for the sake of survival; the most pathetic and miserable existence imaginable.

I can't believe we're looking at having to spend our entire lives bald(ing) yet everyone is so damn willing to daydream their youth away.

Jesus dude, go watch a video of kittens or something, every post I see you make is just a huge downer haha

 

[hellouser]

And yet most hair loss treatments that failed thus far were products of hard scientific work too.

Doesn't matter. The outcome of one doesn't determine the outcome of another.

 

[pegasus2]

I never said it wasn't going to work. I just said absolutely no other viable treatment has worked thus far and we've absolutely no reason to count on this working as all we have are promises made by companies that make money by making promises.

You think I'm not hopeful? Of course I am - it's just that I'm even more terrified we're not doing enough or certainly not everything we would be doing if we knew all these promising treatments would eventually fail. I'm scared we're being complacent.

I mean, fast forward 15 years to a hypothetical situation where every single one of these treatments turned out to be a bust. How do you reconcile yourself to not having fought harder just because you assumed things would turn out alright on their own? It's our lives that are at stake, of course I am not fine with a cure coming in 20 years' time. No one should be.

No treatment has come out in the last 30 years that surpasses finasteride and minoxidil, so that shows its really hard to cure this problem, and this reasonable to assume nothing in the pipeline is going to do it either. However, for millions of years humans had ZERO working treatments for baldness until finasteride and minoxidil became available within just a few years of each other. Since then, there have been a few other discoveries that work as well, or a little better, than those two. Among those are adenosine, bimataprost, and dutasteride. So it's also reasonable to say that progress is expanding exponentially, and it won't be long before one of these researchers blows it out of the water with a full blown cure.

 

[Follisket]

Jesus dude, go watch a video of kittens or something, every post I see you make is just a huge downer haha

Hahah, god, I can't even argue with that.
Anyway, I sure hope you guys are right. It's just incredibly hard to stay positive when you're racing the clock and pushing 30.

 

[hellouser]

Hahah, god, I can't even argue with that.
Anyway, I sure hope you guys are right. It's just incredibly hard to stay positive when you're racing the clock and pushing 30.

Some of us are past 30....

 

[yellowbluegrey]

Now wondering what the average age is on these forums, under or over 30?

 

[mr_robot]

Some of us are past 30....

and 40

 

[That Guy]

Now wondering what the average age is on these forums, under or over 30?

I'm 24, so there is hope for me =P

I feel like another FAQ thread may be needed.

 

[Torin]

If for some horrible reason the Tsuji project didn't work out, I'm sure that Dr. Tsuji would be very humble and honest about it. He would release a press statement detailing the issues they faced and were unable to overcome.

He wouldn't string the thing along for years and years like Histogen.

Hopefully it will work though. I believe in Tsuji, Riken and their partners.

 

[hellouser]

If for some horrible reason the Tsuji project didn't work out, I'm sure that Dr. Tsuji would be very humble and honest about it. He would release a press statement detailing the issues they faced and were unable to overcome.

He wouldn't string the thing along for years and years like Histogen.

Hopefully it will work though. I believe in Tsuji, Riken and their partners.

Except that Histogen hasn't done that. Sure it's taking a while but that's largely thanks to SkinMedica's bullshit TWO lawsuits that set them back a number of years and cost them millions of dollars.

Complaints to SkinMedica can be made here:
https://www.facebook.com/skinmedica/

 

[Torin]

Except that Histogen hasn't done that. Sure it's taking a while but that's largely thanks to SkinMedica's bullshit TWO lawsuits that set them back a number of years and cost them millions of dollars.

Complaints to SkinMedica can be made here:
https://www.facebook.com/skinmedica/

Hey hellouser,

Yes I was aware of the court case they went through.

It's just that, when comparing Riken's work on mice and artificial skin to the Histogen headshot photo of a guy with big circles on his head taken in Ziering's office, well yeah.

I don't think Histogen will work. Maybe they will release hsc to much fanfare but I don't think it will be effective in any way shape or form. Period. In fact I even have more faith in Replicel than I do Histogen.

All this is my opinion of course. We will know in the next few years anyway.

One thing's for sure, things can't go on this way indefinitely with Histogen. It can't get to 2023 with Dr. Naughton talking about a possible 2024 release date in Guyana or San wherever.

No, I think they'll release something around 2020/21 along with some excuses for this or that, maybe change the language up to one of "maintenance" and it will be another prp. Hopefully Tsuji will be growing mohawks on humans by then.

 

[jc3303]

Hey hellouser,

Yes I was aware of the court case they went through.

It's just that, when comparing Riken's work on mice and artificial skin to the Histogen headshot photo of a guy with big circles on his head taken in Ziering's office, well yeah.

I don't think Histogen will work. Maybe they will release hsc to much fanfare but I don't think it will be effective in any way shape or form. Period. In fact I even have more faith in Replicel than I do Histogen.

All this is my opinion of course. We will know in the next few years anyway.

One thing's for sure, things can't go on this way indefinitely with Histogen. It can't get to 2023 with Dr. Naughton talking about a possible 2024 release date in Guyana or San wherever.

No, I think they'll release something around 2020/21 along with some excuses for this or that, maybe change the language up to one of "maintenance" and it will be another prp. Hopefully Tsuji will be growing mohawks on humans by then.

People need to look at data FIRST when it comes to a treatment, it is a lot more important than pictures. Histogen works and the odds are good it will release in mexico 2017/2018 imo (if they've actually started phase III trials). They'll want the tourist dollars in Mexico

 

[Torin]

Dr. Takashi examining what look like high norwoods. From the program 'Science View':

 

[Xaser94]

http://www.scientistlive.com/conten...ogy-shows-promise-regenerating-hair-follicles

New article mentioning the partership between Kyocera and Riken. Highlighted the most interesting aspects from the article imo.

Kyocera, along with RIKEN and Organ Technologies, has launched a joint research to develop a regenerative medical treatment for hair loss, targeting practical use in 2020.

The partnership aims to develop technologies and products for treating hair loss by regenerating hair follicles. Because no existing treatment can increase the number of hair follicles, any viable method of regenerating hair follicles has great potential to succeed.

The joint research works on a technology to collect stem cells from the patient’s own hair follicles, followed by the processing of these follicles and autografting on the same patient. For the treatment of androgenic alopecia (the most common type), a small number of hair follicles will be collected, from which stem cells will be isolated, cultured and amplified to produce hair follicle germ.

The regenerated hair follicle germ will be packaged and delivered to a medical facility for use in transplantation therapy for the patient. The method furthermore allows control of the hair colour by adding pigment stem cells, and the number of hair follicles regenerated.

Kyocera is responsible for technical aspects such as the development of cell processing devices. While various methods are under evaluation, Kyocera’s piezoelectric technology is of particular interest as a means of discharging small amounts of viscid cells in a precise manner during the cell processing process.

Kyocera is expanding its expertise in creating medical components for orthopedic joint replacement and dental implants to support this future application of regenerative medicine.

Kyocera, RIKEN and Organ Technologies are aiming for clinical research in Fiscal Year 2019 (Year ending March 31, 2019), with the goal to put the technologies into practical use in 2020.


Clinical research in 2019, practical use by 2020!!!!!!

 

[hellouser]

http://www.scientistlive.com/conten...ogy-shows-promise-regenerating-hair-follicles

New article mentioning the partership between Kyocera and Riken. Highlighted the most interesting aspects from the article imo.

Kyocera, along with RIKEN and Organ Technologies, has launched a joint research to develop a regenerative medical treatment for hair loss, targeting practical use in 2020.

The partnership aims to develop technologies and products for treating hair loss by regenerating hair follicles. Because no existing treatment can increase the number of hair follicles, any viable method of regenerating hair follicles has great potential to succeed.

The joint research works on a technology to collect stem cells from the patient’s own hair follicles, followed by the processing of these follicles and autografting on the same patient. For the treatment of androgenic alopecia (the most common type), a small number of hair follicles will be collected, from which stem cells will be isolated, cultured and amplified to produce hair follicle germ.

The regenerated hair follicle germ will be packaged and delivered to a medical facility for use in transplantation therapy for the patient. The method furthermore allows control of the hair colour by adding pigment stem cells, and the number of hair follicles regenerated.

Kyocera is responsible for technical aspects such as the development of cell processing devices. While various methods are under evaluation, Kyocera’s piezoelectric technology is of particular interest as a means of discharging small amounts of viscid cells in a precise manner during the cell processing process.

Kyocera is expanding its expertise in creating medical components for orthopedic joint replacement and dental implants to support this future application of regenerative medicine.

Kyocera, RIKEN and Organ Technologies are aiming for clinical research in Fiscal Year 2019 (Year ending March 31, 2019), with the goal to put the technologies into practical use in 2020.


Clinical research in 2019, practical use by 2020!!!!!!

3 more years before clinical trials start... damn, why can't we start this year? What's the obstacle?

 

[Billy-D2016]

http://www.scientistlive.com/conten...ogy-shows-promise-regenerating-hair-follicles

New article mentioning the partership between Kyocera and Riken. Highlighted the most interesting aspects from the article imo.

Kyocera, along with RIKEN and Organ Technologies, has launched a joint research to develop a regenerative medical treatment for hair loss, targeting practical use in 2020.

The partnership aims to develop technologies and products for treating hair loss by regenerating hair follicles. Because no existing treatment can increase the number of hair follicles, any viable method of regenerating hair follicles has great potential to succeed.

The joint research works on a technology to collect stem cells from the patient’s own hair follicles, followed by the processing of these follicles and autografting on the same patient. For the treatment of androgenic alopecia (the most common type), a small number of hair follicles will be collected, from which stem cells will be isolated, cultured and amplified to produce hair follicle germ.

The regenerated hair follicle germ will be packaged and delivered to a medical facility for use in transplantation therapy for the patient. The method furthermore allows control of the hair colour by adding pigment stem cells, and the number of hair follicles regenerated.

Kyocera is responsible for technical aspects such as the development of cell processing devices. While various methods are under evaluation, Kyocera’s piezoelectric technology is of particular interest as a means of discharging small amounts of viscid cells in a precise manner during the cell processing process.

Kyocera is expanding its expertise in creating medical components for orthopedic joint replacement and dental implants to support this future application of regenerative medicine.

Kyocera, RIKEN and Organ Technologies are aiming for clinical research in Fiscal Year 2019 (Year ending March 31, 2019), with the goal to put the technologies into practical use in 2020.


Clinical research in 2019, practical use by 2020!!!!!!

Thanks for sharing Xaser94. I'm not sure what they mean by 'clinical research in 2019' . Is this like a Phase 3 Trail?
Also the publication seems to suggest that they can amplify stem cells to create primordiums without any limit? Would this mean unlimited hair from a small biopsy?? Seems too good to be true!!

 

[buckthorn]

I feel like another FAQ thread may be needed.

Please do!! It would be nice for us to have all the info concisely broken down in one place. Your other faq thread was nice. Just know that it will be mucked up again in two days time!!