Dr. Tsuji Kyocera, Riken Research, Organ Technologies Form Regenerative Hair Research Team

[Pray The Bald Away]

sorry, i meant an injector with multiple needles, not chambers. like the injector replicel developed, which has 16 needles.

Okay, thanks. How would that solve guiding nylon thread problem? We can't have 60,000 nylon threads on our head.

 

[Ken1983]

Okay, thanks. How would that solve guiding nylon thread problem? We can't have 60,000 nylon threads on our head.

?
I thought they patented a guide. The nylon guide was just used in the initial stages, the bio absorbable guide will be used during the procedure, which will naturally fall out of the transplant site or decompose...

 

[Swoop]

Seems that the primordium would be approximately around 0.5mm in length and approximately 0.15mm in width?

Damn this is so great.

 

[Swoop]

Punch size: 0.7mm , 4mm length

Implantation: Choi implanter pen 0.6 & 0.8mm

These were my specifics when I had my hair transplant. I believe the 0.6mm pen was used for transplantation of single grafts and the 0.8mm for doubles and triples in my case.

Look at 5 minute 17 there you can see how a 2's graft is being placed into a implanter pen before delivered to the scalp. That's probably a 0.8mm pen.

 

[Pray The Bald Away]

Punch size: 0.7mm , 4mm length

Implantation: Choi pen 0.6 & 0.8mm

These were my specifics when I had my hair transplant. I believe the 0.6mm pen was used for transplantation of single grafts and the 0.8mm for doubles and triples in my case.

Do you know how he'll get around having to use a nylon thread to guide the hairs? His newest paper was still using this method.

 

[Ken1983]

Do you know how he'll get around having to use a nylon thread to guide the hairs? His newest paper was still using this method.

https://www.google.com/patents/US20140037592

 

[Pray The Bald Away]

https://www.google.com/patents/US20140037592

You're the man! Thanks!

 

[Swoop]

From the patent;

• The regenerative organ germ for transplantation into which the guide has been inserted can be transplanted to a target site by a method known to those skilled in the art. For example, when transplanting a regenerative hair follicle germ, it can be transplanted by using a hair transplant which utilizes the Shapiro hair transplant technique or the Choi hair transplant device or an implanter which utilizes air pressure or the like. The Shapiro hair transplant technique is a method in which a graft wound is created at the transplant site using a micro scalpel or the like and then the hair transplant is transplanted using tweezers. When applying this kind of hair transplant technique, since the regenerative organ germ for transplantation provided by the present invention has a guide, it is possible to operate without directly touching the regenerative hair follicle germ by picking up the guide, and the operation can be therefore easily performed.

• The transplantation depth of the regenerative organ germ can be appropriately modified depending on the organ which is the target of regeneration. For example, when transplanting a regenerative hair follicle germ, the depth is preferably 0.05 to 5 mm, more preferably 0.1 to 1 mm, and most preferably 0.3 to 0.5 mm. In particular, when transplanting a regenerative hair follicle germ into a recipient, it is preferably transplanted into the dermic layer, and more preferably above the boundary surface between the dermal and subdermal tissue at which the hair follicle formation and subsequent hair growth efficiency is excellent. It is also preferable to adjust the transplantation depth so that the top end of the epithelial cell portion of the regenerative hair follicle germ is exposed at the top end of the graft wound because this can increase the continuity with the epithelial cells of the recipient.

I wonder if they won't automate this process though? I mean if these germs would go to a clinic and would need to be injected/delivered to the scalp by a human hand this would be time consuming as hell, skill would also be needed.

Plus I imagine that would be expensive as hell?

Outline of Business Model
Follicular regenerative medicine will focus on the collection of stem cells from the patient’s own hair follicles, followed by the processing of these follicles and autografting on the same patient. For the treatment of androgenic alopecia (the most common type), a small number of hair follicles will be collected, from which stem cells will be isolated, cultured and amplified to produce hair follicle germ by the established organ primordium method. The regenerated hair follicle germ will be packaged and delivered to a medical facility for use in transplantation therapy for the patient.

 

[Ken1983]

hmm, so it looks like they wont be using an injector after all.

 

[Torin]

The method sounds excruciatingly complicated in almost every sense.

I hope Dr. Tsuji really believes that this has the potential to be mass marketed and is not just doing it to prove its viability in humans or to treat a very few select people (say the top 0.1% elites of Japan and the world) carried out by himself and his staff who would be the only ones capable of this.

How I wish Follica would just hurry up and come up with some goodies. Their method is remarkably simple and mass marketable. It could be licenced easily to clinics worldwide, which I think is their aim.

Now if only they could grow hair...

 

[Pray The Bald Away]

From the patent;




I wonder if they won't automate this process though? I mean if these germs would go to a clinic and would need to be injected/delivered to the scalp by a human hand this would be time consuming as hell, skill would also be needed.

Plus I imagine that would be expensive as hell?

This is kind of encouraging because it means there will be little risk for pili multigemini so anyone with retrograde alopecia can get the sides and back filled in.

 

[hilbert]

From the patent;




I wonder if they won't automate this process though? I mean if these germs would go to a clinic and would need to be injected/delivered to the scalp by a human hand this would be time consuming as hell, skill would also be needed.

Plus I imagine that would be expensive as hell?

haha.. transplant. now it makes full sense. now i believe this will be viable and marketable worldwide. come tsuji, hurry up.

 

[pegasus2]

From the patent;




I wonder if they won't automate this process though? I mean if these germs would go to a clinic and would need to be injected/delivered to the scalp by a human hand this would be time consuming as hell, skill would also be needed.

Plus I imagine that would be expensive as hell?

If they don't then it's going to be very important to hold onto, and regrow as much hair as you can through medication in the meantime. Imagine how expensive it would be to have an entire NW7 scalp done by hand.

 

[hellouser]

haha.. transplant. now it makes full sense. now i believe this will be viable and marketable worldwide. come tsuji, hurry up.

Not really... there wouldnt be any time required to 'harvest' each individual graft, it'd only require implanting.

 

[Swoop]

If they don't then it's going to be very important to hold onto, and regrow as much hair as you can through medication in the meantime. Imagine how expensive it would be to have an entire NW7 scalp done by hand.

Let's assume a NW6 guy would normally need 15K grafts with an average hair follicle count of 2. That's 30K hair follicles.

If 1 primordium = 1 hair follicle that would mean implanting 30K primordiums.

Then again if you look at the study...

To achieve hair follicle regeneration at hair densities of 120 or 60–100 hair shafts cm−2 of normal scalp or in FUT treatment41, respectively, twenty-eight bioengineered hair germs were transplanted into a cervical skin circle with a diameter of 1 cm. At 14 to 21 days after transplantation, the bioengineered hairs were erupted at a high density of 124.0±17.3 hair shafts cm

28 germs made a 100+ hair shaft density in the rodent model. Hmm?

 

[Pray The Bald Away]

I wonder if this method will be able to achieve 200 hairs per cm^2. This is going to be insanely expensive for me to get the top and sides filled in. I'd be willing to go up to $50,000 but that would probably be pretty close to the maximum I'd pay.



Who am I kidding? I'd sell my soul for a full head.

 

[Dnpuntold]

I wonder if this method will be able to achieve 200 hairs per cm^2. This is going to be insanely expensive for me to get the top and sides filled in. I'd be willing to go up to $50,000 but that would probably be pretty close to the maximum I'd pay.



Who am I kidding? I'd sell my soul for a full head.

50,000seemswayoverpricedI'mexpectingsomethingin the lines of 15,000 euro but who knows

 

[kuba197]

I wonder if this method will be able to achieve 200 hairs per cm^2. This is going to be insanely expensive for me to get the top and sides filled in. I'd be willing to go up to $50,000 but that would probably be pretty close to the maximum I'd pay.



Who am I kidding? I'd sell my soul for a full head.

50 000? so I keep fingers for Replicel and their 1000 $ treatment....

 

[Ken1983]

Mind you that patent was made well before the kyocera deal, so they may not use chois transplant device. The primdormiums

28 germs made a 100+ hair shaft density in the rodent model. Hmm?

So it would take a little over 4000 germs to generate 30,000 hairs, assuming there is an average of 2 hairs per follicle.



Lets hope the mass production of the primordiums will be as simple and cost effective as possible..

 

[I.D WALKER]

Mind you that patent was made well before the kyocera deal, so they may not use chois transplant device. The primdormiums


So it would take a little over 4000 germs to generate 30,000 hairs, assuming there is an average of 2 hairs per follicle.



Lets hope the mass production of the primordiums will be as simple and cost effective as possible..

Yes let's hope our hope is well invested.