El-Duterino/some q on AA....

Dani_uk

Established Member
Reaction score
0
Hi there,

After reading your recent posts El dutasteride, I have some q for ya...

1. You have said that your hair has never been sooo good since you started any form of hair loss treatments, until with your latest (2x2 Fluridil,dutasteride and Fut) regimen. Is that true? If so how did you evalulate it- any growth or stabilised hair loss and increased hair size???

2. I am v keen in Adding Fluridil to my artillery and your recent posts make me more eager. However, I dont want to use Flutamide at all. Do you think your presrnt results could be due to Flutamide and/or Fluridil?

3. You also mentioned some new drugs currently under the microscope i.e. Cosmo (?). Will this be like fluridil i.e.water intolerant and any idea when it will be available.

4. Whats the half life of Fluridil and will one 2ml topical be ok? I see that you use 2x2ml. Does this increased dose have any side effects and will increasing the dose have any added benefit? What do the studies say? ( I cant access/find any studies).
 

el_duterino

Senior Member
Reaction score
397
Dani_uk said:
Hi there,

After reading your recent posts El dutasteride, I have some q for ya...

1. You have said that your hair has never been sooo good since you started any form of hair loss treatments, until with your latest (2x2 Fluridil,dutasteride and Fut) regimen. Is that true?
>its true. I have no reasons to make this up. I used other things that did not work, such as curcumin/resveratrol combo.I would never use this fluridil if it was not working. My hair is more important than libido or other side effects, if I had no other choices. Side effects or liver issues don't scare me. Rather die young with a hairy head than live bald.

If so how did you evalulate it- any growth or stabilised hair loss and increased hair size???
>no new growth. Anti-androgens will not regrow new hair as a rule. There are some exceptions, if the loss is very recent for example. read the research on castrated men & hairloss (google)
I have no more hairloos, and thicker and more pigemented (darker) hair now.


2. I am v keen in Adding Fluridil to my artillery and your recent posts make me more eager. However, I dont want to use Flutamide at all. Do you think your presrnt results could be due to Flutamide and/or Fluridil?

>I stopped flutamide a few weeks ago and was using it 2 or 3 weeks a day only, and only at the hairline. i am sure that the results are from fluridil. I would be going downhill very fast if it would not be doing anything since I also reduced my dutasteride amount by half .

3. You also mentioned some new drugs currently under the microscope i.e. Cosmo (?). Will this be like fluridil i.e.water intolerant and any idea when it will be available.

>This looks like water will be no issue. They still have not tested its effectiveness on hairloss though, only the side effect/systemically absorbtion of antiandrogen.

Fluridil is designed to break-down in water/blood to protect us from side effects so that it will not be systemically absorbed as an anti-androgen. the break-down molecules are not anti-androgenic.

4. Whats the half life of Fluridil and will one 2ml topical be ok?
the amount depends on how aggressive your hairloss is. And I strongly advise an oral anti-androgen as a combo, such as dutasteride or finasteride for best results. I never stopped dutasteride even when I was on Flutamide or RU58841.
Ther is no serum half life since it breaks down in blood.

I see that you use 2x2ml. Does this increased dose have any side effects and will increasing the dose have any added benefit?

>No side effects at all, because it breaks down in blood whether you use 1 or 4 ampules. Side effects are not dose dependant.

Fluridil is a bit less powerful than flutamide if taken once a day at the recommended dose becuase inhibiting androgen receptors is harder to do than blocking them by binding an androgen-antagonist to them. So if you have more aggressive hairloss you need to have more AR inhibition, thus more fluridil. try 1 ampule a day and increase dosage if you feel you need more power.
It all depends on how advanced or aggressive your hairloss is.
This is similar to inhibiting DHT...you need more Dutasteride to inhibit more DHT and get better results.
Also, hormones are a signal, which means that you would need to cut the signal to close to 100% to guarantee any aggressive/advanced hairloss to stop.

What do the studies say? ( I cant access/find any studies).

see studies under Bp-766 and do a google search on fluridil. they have just one or two studies on humans but with good results. bp-766 was the name of the compound that was developped in the US before it was commercialized as fluridil.
 

gjp2222

Established Member
Reaction score
0
What bothers me is that every clinical trial is run by the same people, the company itself. No independent entity has ever run a trial. This is very suspicious. Other than yourself, no one on these boards has had success with fluridil. Personally, I used it at one point as a replacement for spironolactone and actually lost ground, but regained it when I switched back.
 

el_duterino

Senior Member
Reaction score
397
do we have human studies on spironolactone ? do we have human studies on RU58841 ? Flutamide ? the answer is no. But all these drugs do work.
Lot of people are suspicious of the studies done by Merck too. But finasteride does work.

My point is that all these drugs do work, you just need to understand how much of the drug you need to use to be able to stop hairloss in your case.

You used 1 ampule a day and lost ground. I used 1 ampule a day & dutasteride ED and lost ground too.
But with 4 amplues a day & dutasteride EOD I maintain very well and with no additional side effects.

Fluridil is the only drug that can be increased and still have no side effects. I never used spironolactone myself so I cannot comment on it, but i am sure that it works.
The question is: will spironolactone be sufficient to completely stop hairloss without any side effects ? probably not.
Fluridil has the potential to do that because the dosage can be freely adjusted, unlike all the other anti-androgen drugs we have.

RU58841 is better than fluridil in terms of effectiveness at same dosage, but there are no long-term studies on its dangers, side effects in humans etc....and besides trying to purchase a good quality batch is very difficult & costly.
Nevertheless, I still bought 10g of RU base powder recently,but I am glad that my hair don't depend on it anymore. I don't know if the quality will be good, and shipping has been delayed by over 1 month.
With fluridil, 3 mouse clicks on a web site and the boxes arrive at my house within 5 days..and I live accross the globe.

sure beats dealing with some dudes in some lab in China that only accepts bank wire.
see:
http://www.hairlosshelp.com/forums/mess ... adid=81435
 

Dani_uk

Established Member
Reaction score
0
What is RU 58841 and how do you obtain and use it?

Have you gone back to using this El-dutasteride?
 

Bryan

Senior Member
Staff member
Reaction score
42
el_duterino said:
do we have human studies on spironolactone ? .... the answer is no.

Sure we do. They've been posted several times.
 

Dani_uk

Established Member
Reaction score
0
Bryan,
What do you think of Fluridil and RU-5881 topicals?
Are there any other good anti androgen products out there?
 

die_hard

Established Member
Reaction score
0
Bryan said:
el_duterino said:
do we have human studies on spironolactone ? .... the answer is no.

Sure we do. They've been posted several times.

Finasteride was an accidental study..
 

Bryan

Senior Member
Staff member
Reaction score
42
Dani_uk said:
Bryan,
What do you think of Fluridil and RU-5881 topicals?

I have an agnostic attitude about fluridil, because it's never been tested by independent doctors and scientists. And the longer it goes without such independent testing, the more and more suspicious I become of it.

On the other hand, RU58841 has been thoroughly tested, at least in animals. I think it's the real deal.

Dani_uk said:
Are there any other good anti androgen products out there?

Not to my knowledge.
 

Bryan

Senior Member
Staff member
Reaction score
42
die_hard said:
Finasteride was an accidental study..

Hey, I just spoke with your parents. They said YOU were an accident! :)
 
Top