Exploring The Hormonal Route. Hair=life.

Mr. Slap Head

Mr. Slap Head

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sg2000 said:
what are you doing now?You were afraid of upoing dose?
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Was already on a high dose of it, massive dose and it wasn’t working. In fact it caused more itching and acne etc. You have to figure, aside from receptor upregulation, it also raises T quite a bit. Bica works by outnumbering the androgens in volume, but molecule for molecule it has a very weak affinity for AR. It’s certainly no match for DHT. The other factor most people don’t realize is that all that excess T can still be converted to DHT via intracellular mechanisms. Even if you are on a 5ARI we already know that the significant blockage occurs in the serum. However, these drugs only block scalp DHT by 50%. This is because, unlike T, DHT is a paracrine hormone (it is produced in the local cells). Thus, the spike in serum T from bica can reach the scalp to the cells of the hair follicle and be converted to DHT. Not all of it, but some of it will be enough to continue to do the damage, especially since the AA will upreg AR.
 
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sg2000

Senior Member
My Regimen
Reaction score
318
Mr. Slap Head said:
Was already on a high dose of it, massive dose and it wasn’t working. In fact it caused more itching and acne etc. You have to figure, aside from receptor upregulation, it also raises T quite a bit. Bica works by outnumbering the androgens in volume, but molecule for molecule it has a very weak affinity for AR. It’s certainly no match for DHT. The other factor most people don’t realize is that all that excess T can still be converted to DHT via intracellular mechanisms. Even if you are on a 5ARI we already know that the significant blockage occurs in the serum. However, these drugs only block scalp DHT by 50%. This is because, unlike T, DHT is a paracrine hormone (it is produced in the local cells). Thus, the spike in serum T from bica can reach the scalp to the cells of the hair follicle and be converted to DHT. Not all of it, but some of it will be enough to continue to do the damage, especially since the AA will upreg AR.
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damn do you think that if you try pyri you will succeed?
 
S

sg2000

Senior Member
My Regimen
Reaction score
318
Mr. Slap Head said:
Was already on a high dose of it, massive dose and it wasn’t working. In fact it caused more itching and acne etc. You have to figure, aside from receptor upregulation, it also raises T quite a bit. Bica works by outnumbering the androgens in volume, but molecule for molecule it has a very weak affinity for AR. It’s certainly no match for DHT. The other factor most people don’t realize is that all that excess T can still be converted to DHT via intracellular mechanisms. Even if you are on a 5ARI we already know that the significant blockage occurs in the serum. However, these drugs only block scalp DHT by 50%. This is because, unlike T, DHT is a paracrine hormone (it is produced in the local cells). Thus, the spike in serum T from bica can reach the scalp to the cells of the hair follicle and be converted to DHT. Not all of it, but some of it will be enough to continue to do the damage, especially since the AA will upreg AR.
Click to expand...
scalp itch and hair loss is very common and i think is mainly a problem with the AR
 
S

sg2000

Senior Member
My Regimen
Reaction score
318
Mr. Slap Head said:
Was already on a high dose of it, massive dose and it wasn’t working. In fact it caused more itching and acne etc. You have to figure, aside from receptor upregulation, it also raises T quite a bit. Bica works by outnumbering the androgens in volume, but molecule for molecule it has a very weak affinity for AR. It’s certainly no match for DHT. The other factor most people don’t realize is that all that excess T can still be converted to DHT via intracellular mechanisms. Even if you are on a 5ARI we already know that the significant blockage occurs in the serum. However, these drugs only block scalp DHT by 50%. This is because, unlike T, DHT is a paracrine hormone (it is produced in the local cells). Thus, the spike in serum T from bica can reach the scalp to the cells of the hair follicle and be converted to DHT. Not all of it, but some of it will be enough to continue to do the damage, especially since the AA will upreg AR.
Click to expand...
on monday i will have my prolactin results.Do you think that it will cause hair loss if high?
 
Mr. Slap Head

Mr. Slap Head

Senior Member
My Regimen
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2,247
sg2000 said:
is he ok if i am not gay and not trans but willing to do this only for hair?
btw mr slaphead did you try dutasteride?Im on 0.5 and i think my libido is much much lower but i still get hard and f*** hot b****s
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I’m not sure. He’s very weird but he might be okay since you’re considering HRT.

Yes dutasteride gave me worse hair. You can read about reports on this, it happens for some people. Interestingly I didn’t have that bad of sides, which makes sense since hair was worse and acne too. That’s upregulation for you.
sg2000 said:
do you guys think my hair loss is bad?What should i do to keep my current hair state for like 4ever?
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You have solid hair. If you are concerned about maintaining, you really don’t need that extreme of a regimen. Unless you want regrowth. Personally I would focus on a healthy regimen that is sustainable long term. If you go on HRT, imagine how much the drug will affect you since you are already sensitive to dutasteride. I’d make slight changes to your regimen to maintain, and go to a top transplant doctor.
 
S

sg2000

Senior Member
My Regimen
Reaction score
318
Mr. Slap Head said:
I’m not sure. He’s very weird but he might be okay since you’re considering HRT.

Yes dutasteride gave me worse hair. You can read about reports on this, it happens for some people. Interestingly I didn’t have that bad of sides, which makes sense since hair was worse and acne too. That’s upregulation for you.

You have solid hair. If you are concerned about maintaining, you really don’t need that extreme of a regimen. Unless you want regrowth. Personally I would focus on a healthy regimen that is sustainable long term. If you go on HRT, imagine how much the drug will affect you since you are already sensitive to dutasteride. I’d make slight changes to your regimen to maintain, and go to a top transplant doctor.
Click to expand...
wich kind of slight changes?I dont wanna hear about hair transplants anymore!f*** that i just want to maintain this baseline as long as i live
 
losingbattle88

losingbattle88

Senior Member
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3,093
sg2000 said:
10 months dutasteride and 8 months. on 5 oral min
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Dutasteride for 1.5 years destroyed my hair and gave sexual sides. Finasteride gave me a permanent sexual side effect. These drugs sucks. I also used oral min for 5 months while on Dutasteride. 15 to 20mg. Did f*** all. Im today way better off hairloss drugs.
 
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