4mg E is too low of a dose to interrupt HPG axis. As long as its intact, it'll interact with adrenal axis for example, or thyroid axis to randomly mess with your hair, and not only with the help of T itself. When it stops, your system starts to learn how to function without it and becomes more stable.
E is important too, but only in conjunction with below female range T. I see it working smth like this:
There is female pattern hair growth cycle and male one. If yours is something inbetween, there will always be problems. To switch to female one, you will need to simulate the cis woman hormone profile, which is: E2: 150pg/ml on average, T: <40ng/dl, DHT: <10ng/dl. If your T isn't supressed enough, your system will always find a way to upregulate smth, or use some backdoor pathway to screw up your growth cycle making it not completely female, no matter what amount of DHT you have.
Ok, good to know. The only problem is that E pills could pretty much be worse for your liver than cypro itself long term, plus cardiovascular complications. The only way you can use them more or less safe is sublingual route, but its a pain in the ***, considering you will need to do it 3 times a day for somewhat stable E levels and half of the pill will still (kill bill) reach your stomach. Either way, wouldn't recommend mono or dosage more than 4mg on pills.
The only good options are scrotal application of gel and injections (best choice imo). GNRH agonist if needed (if you're rich). Bicalutamide might help too, but its better to use low dose of it and when your T is already near female range.
2.5 mg is a non-Hrt dose (which rarely works). When you include E and/or progestins to your regime, there are just extra interactions that you might not want and lack of benefit ( especially if you don't want to do too many blood tests if smth goes wrong). So i recommend tapering off that sh*t very slowly (-0.5mg every 2 month) until the standard dose of 0.5mg is reached. Ofc you'll need your T to be nuked by that time.
---I'm a lil tipsy and started to forget english while typing all this crap, but hope it'll help somehow.
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