Exploring The Hormonal Route. Hair=life.

[Ikarus]

[UPDATE] I have been using bicalutamide for fourteen days, and I would like to mention some notable changes. It has been three days since I last washed my hair, and my scalp still doesn't have sufficient sebum production to make my hair greasy. I believe I could go without washing my hair for a couple more days without my hair becoming greasy, although I wouldn't do that since that seems slightly 'germy' to me. Due to this, I will readjust the amount of times I wash my hair from it's prior amount (EOD) to every fourth day. Additionally, I believe the itching was due to over-washing my hair since the itching has reduced accordingly.

Furthermore, sebum production on my face appears to have significantly reduced in comparison to when I was on spironolactone. Previously I would continue to produce sufficient amount of sebum within the t-zone to produce minuscule whiteheads, which isn't an apparent issue since starting bicalutamide. I can't categorise myself as a truly dry skin-type, although I could classify my skin-type as 'falsely dry' since dry skin isn't my genetic skin-type. I definitely will have to modify my skincare routine to fit these changes.

 

[Ikarus]

in the future i might try to add Bicalutamide to my regime, thank you for the scientific research you're doing, it's appreciated.

I will post significant amounts of photos eventually, which hopefully will help others! There are around two or three users of bicalutamide and only one of them have uploaded pictures, in which he already had great hair.

 

[Yar]

not. I don't care for blood tests. if necessary I will take 400 mg. more than antidor.

What is your regime today? Do you have a gyno? Do you masturbate? How often?

 

[Mr. Grey]

I am not kidding. 50 mg a day doesn't help me anymore.

Man, what exactly do you mean - don’t work??
You still lose hair, or don’t have improved? Or maybe you have morning wooden?))
50 mg it is huge dosage, it impossible, CPA do not make overflow. Go to the doctor and make blood test (hormones). CPA has commulative effect and with some period of time accumulate in your organism.

 

[Marky]

I apply estrogel once a day. I take a relatively small dose of 2.5 g once in the morning. Some days I take 3.75 g of gel.

Wolf I think you when you started some areas started to look better while some worse, I assume that evened out in the end. Or did it continue as in general it was getting better overall.

 

[Marky]

I noticed too that I no longer felt like I was starving all the time. I haven't gained weight but I don't eat as much either so I think my metabolism slowed.

and testosterone does increase metabolism:

"basal metabolic rate (BMR) increased significantly after 3 months of testosterone treatment "
https://www.ncbi.nlm.nih.gov/m/pubmed/1730811/

"Testosterone and dehydroepiandrosterone stimulate RMR, in part, directly and, in part, through their effects on body composition (30)."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645618/

This is very bad because in nature creatures with slower metabolisms live longer. The more food required equals more toxic byproducts of metabolism. That's one main reason why calorie restriction extends lifespan. Amongst these similiar aged monkeys, the one on the right has restricted calories.

View attachment 120355

Also, CR slows metabolism. This is also why I believe too much muscle would also contribute to the aging process. Because bigger muscles consume more energy even while at rest. The more muscle one has, the more calories required to be able to maintain it which again leads to more toxic byproducts of metabolism; homocysteine, oxidation, glycation end products, etc.
Yet people get power and strength confused with health and longevity and the media glorifies testosterone. Women have less muscle and live longer than men, they also have slower metabolisms cause the reality is that the candle glowing twice as bright lasts half as long.

Thats interesting, but could there be value in moderate exercise - I mean there would be the point of overkill for sure.
I do a couple times a week and I feel incomplete without it. I think it would play a part in preserving DNA regeneration, ultimately you're breaking the muscle down then it regrows stronger.

 

[bridgeburn]

I think it would play a part in preserving DNA regeneration, ultimately you're breaking the muscle down then it regrows stronger.

sometimes just because something makes sense doesn't mean its true.

"Endurance but not resistance training has anti-aging effects"
https://www.eurekalert.org/pub_releases/2018-11/esoc-ebn112618.php

"Although calorie restriction can result in reduced muscle mass, the diet is able to preserve the quality and function of muscle with age. In rhesus monkeys, calorie restriction appeared to delay the onset of sarcopenia with age, and this is similar to what is seen in mice that are subjected to CR [4]. "

 

[Marky]

sometimes just because something makes sense doesn't mean its true.

"Endurance but not resistance training has anti-aging effects"
https://www.eurekalert.org/pub_releases/2018-11/esoc-ebn112618.php

"Although calorie restriction can result in reduced muscle mass, the diet is able to preserve the quality and function of muscle with age. In rhesus monkeys, calorie restriction appeared to delay the onset of sarcopenia with age, and this is similar to what is seen in mice that are subjected to CR [4]. "

Then ideally light weight and high rep might be best, again in moderation, it is a form of endurance training over speed and power.
This guy only eats one meal a day, great info if you can understand WTF he's saying, great shape too:

 

[bridgeburn]

Then ideally light weight and high rep might be best, again in moderation, it is a form of endurance training over speed and power.
This guy only eats one meal a day, great info if you can understand WTF he's saying, great shape too:

he's bald as f*** though. not a good sign lol

 

[Marky]

he's bald as f*** though. not a good sign lol

Ya exactly never even thought of that, maybe goes to show you once again that things like this might play a small factor in it (CR that is), but the big factor is always hormone receptivity in the follicles.

 

[bridgeburn]

"When you spread your meals throughout the day, your stomach and digestive system don't have to work as hard. If you eat just one meal, however, there is increased pressure on your digestive system to work through all that food. Your heart must work harder to send extra blood to your gut, which can raise your blood pressure levels over time. If you're susceptible to heartburn, a big meal also raises your risk of suffering from acid reflux.

In clinical trials, scientists have discovered that eating a single meal a day has negative health effects in the long term. In one study published in 2007 in the journal "Metabolism," subjects who had all of their daily calories in one meal developed higher blood sugar levels and elevated levels of ghrelin, a hormone that controls appetite. The researchers concluded that over time, eating a single meal daily could put people at higher risk of developing serious conditions such as diabetes, stroke and heart disease."

https://www.livestrong.com/article/542042-is-eating-one-meal-a-day-healthy/

"One study in published in JAMA involving 100 people found that intermittent fasting raised LDL cholesterol (bad cholesterol). Higher levels of LDL cholesterol are linked to increased rates of heart disease and stroke."

https://www.medicalnewstoday.com/articles/320125.php

 

[nWo Wolfpac]

Wolf I think you when you started some areas started to look better while some worse, I assume that evened out in the end. Or did it continue as in general it was getting better overall.

When I started i noticed my hair was getting worse especially my temples. Then my temples started getting better while the rest of my hair kept getting worse. After the first 3 months it started getting better everywhere.

 

[nWo Wolfpac]

"When you spread your meals throughout the day, your stomach and digestive system don't have to work as hard. If you eat just one meal, however, there is increased pressure on your digestive system to work through all that food. Your heart must work harder to send extra blood to your gut, which can raise your blood pressure levels over time. If you're susceptible to heartburn, a big meal also raises your risk of suffering from acid reflux.

In clinical trials, scientists have discovered that eating a single meal a day has negative health effects in the long term. In one study published in 2007 in the journal "Metabolism," subjects who had all of their daily calories in one meal developed higher blood sugar levels and elevated levels of ghrelin, a hormone that controls appetite. The researchers concluded that over time, eating a single meal daily could put people at higher risk of developing serious conditions such as diabetes, stroke and heart disease."

https://www.livestrong.com/article/542042-is-eating-one-meal-a-day-healthy/

"One study in published in JAMA involving 100 people found that intermittent fasting raised LDL cholesterol (bad cholesterol). Higher levels of LDL cholesterol are linked to increased rates of heart disease and stroke."

https://www.medicalnewstoday.com/articles/320125.php

I hope that's true because I could never force myself to eat one giant meal a day.

 

[Ikarus]

When I started i noticed my hair was getting worse especially my temples. Then my temples started getting better while the rest of my hair kept getting worse. After the first 3 months it started getting better everywhere.

That’s what’s happening to me currently... Although my temples are continuously improving, the rest makes me fearful!

 

[LEXUS]

take progesterone and dutasteride instead that high dosage of cpa

it is the androstendione from yr adrenal gland

androstendione dont use an androgenreceptor to get in in yr cell... cpa is useless for androst.

I tried. when I take progesterone, my testosterone and libido increase and my hair is greasy. It does not work for me. Thank you all for your concern. Why do you all say that there is no point in taking more than 50 mg of CPA? I seem to understand what's the matter. I stopped taking avodart. As soon as I added Avodart two days ago, everything became better. CPA can not remove dht. only avodart.

 

[Ikarus]

I tried. when I take progesterone, my testosterone and libido increase and my hair is greasy. It does not work for me. Thank you all for your concern. Why do you all say that there is no point in taking more than 50 mg of CPA? I seem to understand what's the matter. I stopped taking avodart. As soon as I added Avodart two days ago, everything became better. CPA can not remove dht. only avodart.

If there isn’t any testosterone to convert to DHT, why would you need a 5AR inhibitor? You are using cyproterone acetate and 6MG/day of estradiol; I highly doubt you have much testosterone in sight. I am mostly concerned with your dose of CPA and its significant risks whilst you not monitoring yourself.

 

[LEXUS]

How then to remove androstenedione? spironolactone can help?

 

[LEXUS]

If there isn’t any testosterone to convert to DHT, why would you need a 5AR inhibitor? You are using cyproterone acetate and 6MG/day of estradiol; I highly doubt you have much testosterone in sight. I am mostly concerned with your dose of CPA and its significant risks whilst you not monitoring yourself.

likemike said that dht appears from androstenedione. I made sure that CPA can only remove testosterone. androstenedione and dht he can not remove. the only reason the hairs drop out is dht. just when there is no testosterone, then dht appears from androsterone.

 

[LEXUS]

What is your regime today? Do you have a gyno? Do you masturbate? How often?

I have no problems with ananizm. there is no gino. more than 1 size cannot grow. My regime I just strengthened. You can look at him. Just do not fall. I want everything at once.

from today my mode is like that. CPA 300 mg, spironolactone 600 mg, Avodart, Estrogel, Estradiol, Finasteride, minoxidil.

 

[I'mme]

Everyone doesn't get everything. I saved my hair but prevented masculinization. There are people who think I'm 12 when I'm about to turn 20 in a couple of months. I can be jealous of you all who has to deal with hair loss when you completed your puberty.
Just kidding. I like looking younger. And with bicalutamide and metformin, I'll be stuck at this 12 years of age forever.
#PeterPanSyndrome

Hello @Ein , fellow Indian here.
Sorry, I've had little trouble deciphering your replies. What you're basically saying is that with 50mg bicalutamide and 1mg fina and 100pmg metformin, you were able to stop your hairloss and you didn't get any sexual/feminizing side effects and are still pretty much male?

If that is true, it should give me some hope.