Exploring The Hormonal Route. Hair=life.

[JaneyElizabeth]

Posted by
u/JaneyElizabeth

7 hours ago

Clarification about Monotherapy with Either CPA, MPA, spironolactone or the 'Mides and Safety​

I know many people do this in the XY hair loss community, in terms of only using an AA, which technically, duta and finasteride are too. I have been told that it can cause loss of bone mass and have other negative effects but I don't want to warn them off if unnecessary. It appears to me that Provera and CPA work exactly alike but we mostly use provera as an adjunct for breast finishing. So that would seem to leave spironolactone and bica as primarily receptor blockers.
If any of them raise E and lower T enough, then they should be safe in monotherapy or no? That's their thought as I always warn against more than 90 days single-shot AA.

 

[JaneyElizabeth]

Changing my two patches for a new week. I use two generic Climara 100's. I usually place on buttocks or in the kidney area where they seem to stay better. Arguably the best method of ingestion among all who have insurance since they are pricey.

 

[JaneyElizabeth]

I am waiting for some answers on my single-shot reddit question on reddit. If any of you know the answer please feel free to post over there.

 

[deathdiss]

I am trying to find a scheme that does not lower the T to the female levels. Otherwise, we will get a feminization of the face, body changes. Bicalutamide is good at this, any scheme should include it as a base. It is possible to defeat hair loss with 100mg of Bika and dutasteride for sure, but the price of this treatment is very high, so I am looking for other options. At cost, I can afford the following options:
1) 75mg Bica + finasteride / Duta (if I find a generic)
2) 50mg Bica + finasteride + Estradiol. Estrogel is expensive if you use 2 clicks a day (1 press - 2.5g, 80g in a can). But I don't know what effect one press will have (0.75mg estradiol)

It is very difficult to choose. While I check all the options, I'll go bald

do you have to stick on bica for life or is it a cycle only?

 

[JaneyElizabeth]

do you have to stick on bica for life or is it a cycle only?

We don't know but probably not for maintenance.

 

[JaneyElizabeth]

Clarification about Monotherapy with Either CPA, MPA, spironolactone or the 'Mides and Safety
from shrouded_reflection via /r/AskMtFHRT on my thread.

 

[Norwoody]

You were supposed to explain what the heck that was.

I don't really know lol. "Whatevr" has posted about it. Apparently it's present in the follicle of hairs that aren't miniaturizing and slowly dwindles away after puberty for those with balding scalps.

 

[JaneyElizabeth]

I don't really know lol. "Whatevr" has posted about it. Apparently it's present in the follicle of hairs that aren't miniaturizing and slowly dwindles away after puberty for those with balding scalps.

Eh. I guess it is irrelevant to MtF's.

 

[JaneyElizabeth]

I don't really know lol. "Whatevr" has posted about it. Apparently it's present in the follicle of hairs that aren't miniaturizing and slowly dwindles away after puberty for those with balding scalps.

So many things seem apparent conceptually but then they just don't pan out.

 

[Norwoody]

Yeah correlation vs. causation too

 

[ReturnOfExtreme]

Hair growth and facial feminization and breast growth all are going really well. Lowered my dose of oral min to ~6mg down from 12.5mg to hopefully decrease periphery hair increases. Is yours holding up?

That’s good to hear, any images of your hair for updates? And, mine is doing fine, I had a shed when increasing my estrogen dosage but that was expected

 

[ReturnOfExtreme]

Explain the side effects. Have you become physically weaker, lost muscles? Are you getting fat? ED?

Physically weaker? Yeah. Lost muscles? Yeah. Didn’t have those regardless. Getting fat? No, but my weight has increased due to thicker thighs, etc. Erectile dysfunction? Don’t know, don’t use it.

 

[JaneyElizabeth]

Anyone have a good source for a 2.5mm derma-roller on Amazon. I am getting frustrated because it only returns results for 0.25mm grrr.

 

[JaneyElizabeth]

Yeah correlation vs. causation too

Yes. The prostaglandin folks forget that they are not a double-blind study plus most are using stacks of things.

 

[JaneyElizabeth]

That’s good to hear, any images of your hair for updates? And, mine is doing fine, I had a shed when increasing my estrogen dosage but that was expected

Last ones were February 1st so I will post on my next good hair day which I still have strangely enough. My main need is volume. Any thinning areas are from a transplant that didn't take but derma-rolling can resolve that which is miraculous to me. The other theory of mine is cross-talk which increases blood flow in the follicles that weren't transplanted and even those that took. This would explain why small scars seem not to be visible through a full head of hair.

 

[JaneyElizabeth]

Skin health​

The estrogen receptor, as well as the progesterone receptor, have been detected in the skin, including in keratinocytes and fibroblasts.[62][63] At menopause and thereafter, decreased levels of female sex hormones result in atrophy, thinning, and increased wrinkling of the skin and a reduction in skin elasticity, firmness, and strength.[62][63] These skin changes constitute an acceleration in skin aging and are the result of decreased collagen content, irregularities in the morphology of epidermal skin cells, decreased ground substance between skin fibers, and reduced capillaries and blood flow.[62][63] The skin also becomes more dry during menopause, which is due to reduced skin hydration and surface lipids (sebum production).[62] Along with chronological aging and photoaging, estrogen deficiency in menopause is one of the three main factors that predominantly influences skin aging.[62]

Hormone replacement therapy, consisting of systemic treatment with estrogen alone or in combination with a progestogen, has well-documented and considerable beneficial effects on the skin of postmenopausal women.[62][63] These benefits include increased skin collagen content, skin thickness and elasticity, and skin hydration and surface lipids.[62][63] Topical estrogen has been found to have similar beneficial effects on the skin.[62] In addition, a study has found that topical 2% progesterone cream significantly increases skin elasticity and firmness and observably decreases wrinkles in peri- and postmenopausal women.[63] Skin hydration and surface lipids, on the other hand, did not significantly change with topical progesterone.[63] These findings suggest that progesterone, like estrogen, also has beneficial effects on the skin, and may be independently protective against skin aging.[63]

 

[JaneyElizabeth]

Anyone know why progesterone is P4 and not just P? I assume there are different metabolites that are P1, P2 and P3 as with estrogen. But why isn't DHT called T2? Copyright violations of Arnald's movies?

 

[JaneyElizabeth]

I can easily pull my scalp together from all angles which is supposed to be correlated with a good environment for regrowth.

 

[JaneyElizabeth]

Amazon has none and these companies don't bother to print the gauge on the base or roller so those are useless:

https://www.cosmeticsmegastore.com/us/25-mm-derma-roller-boolavard-tm-titanium-alloy-micro-needle-roller-540-needlesbest-skin-roller/p-13552950-27885146?language=en&ac=cosmeticsmegastore&gclid=CjwKCAiA65iBBhB-EiwAW253W6sSm7gOYDth2MXFBtKPC5_JEUWOvPHw_SNvQ9-4Dk8cQL3whXKWbhoCtOQQAvD_BwE

 

[JaneyElizabeth]

So, 2.5mm roller bought from Cosmetics Megastore for $17 including shipping and no tax apparently so score! I will provide feedback on the 2.5mm gauge.