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- 2,900
Bro if you cant even handle 1mg or get sides at that dosage you really shouldnt be taking it in the first place it could be dangerous for you. I use 12.5mg twice daily and no sides.
Exploring The Hormonal Route. Hair=life.
- Thread starter bridgeburn
- Start date
- Reaction score
- 3
Hey guys, An update as i'm 2 months in my regimen of 12,5mg cypro 0,25 mg duta ed, 5% minoxidil and 6 mg Estrogel Transdermal. I received my lab tests and my T is in the right range 26 ng/dl. Prolactin is slightly above normal (516 mu/l). I guess that's okay to keep there as I'm not planning to increase my Cypro dosage as T is already in preferred range. Only problem is my E needs to be raised as it's 33.3 pg/ml. So far my current hair thickened up but no signs of white dots of any form of new hair growing. I read E needs to be above 200pg/ml to have significant results. Y'all think this is true? Currently I'm applying 6mg everyday, 2mg morning, 2mg afternoon, 2mg evening. What would be the best way to increase my E levels as fast as possible? Y'all advice me to raise Estrogel to maybe 8mg a day or maybe switch to E injections? Anyone with knowdledge or experience commenting is very much appreciated. I want to start my regrowth cycle as fast as possible! 
Test results:
E 33.3 pg/ml
Prolactin 516 mU/l
T 26 ng/dl
Test results:
E 33.3 pg/ml
Prolactin 516 mU/l
T 26 ng/dl
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- Reaction score
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Transdermal. I rub it on my innner tighs.
- Reaction score
- 197
Is it too much.
How is your E1 (800 pg/ml?)
6 mg are 6 hub
1 hub is maybe 0.6 or 0.75 mg E2.. Twice a day must be 300 pg/ml E2
- Reaction score
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Didn't test my E1 unfortunately. I do 2mg E three times a day. I'm planning to upper it to 8mg I think or add E pills. This is something Bridgeburn and Noah both did. I guess all of this will work add pills, higher gel dosage or injections.
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Yeah I saw some impressive results on forums. Wondering if anyone here has experienced a difference in results after switching to injections. It's something I would consider but I need to hear more stories as I'm not a big fan of needles myself haha. But anything for hair.
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I see! So you have better experiences with sublingual than with transdermal? You combine them both or completely switched to sublingual? We might be in the same situation
sublingual administration is a hassle with film coated pills... a lot of the dissolved material is swallowed by accident, it takes a long time to dissolve, and keeping it in place is hard. I recommend sublabial instead, under the lip, between the lips and the gums.
Also you should know that E2 levels drop down significantly within a few hours (depending on the dose) with sublingual/sublabial administration. So you should consider dosing 4 times a day. I take .5mg every 4 hrs, 4 times a day.
Also you should know that E2 levels drop down significantly within a few hours (depending on the dose) with sublingual/sublabial administration. So you should consider dosing 4 times a day. I take .5mg every 4 hrs, 4 times a day.
Noah was kind enough to share some charts with me. https://drive.google.com/drive/folders/1vnNCbPhKpYMlHnfds9YQqAsxjFAxeora?usp=sharing
- Reaction score
- 19
I want to use E2 injections as well, but I do not have health insurance at the moment. I prefer to get E2 from a provider, but I am not sure if I can get health insurance any time soon.
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Thanks for the tip! Is there a reason why you didn't try E gel?
E gel goes systemic anyways, and as you can see in the first chart oral e2 is negligible.
Also the gel is less efficacious, so It would be much more expensive. (at least where I live).
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- 197
Yes, sublingual is more effective... And scrotal too..I see! So you have better experiences with sublingual than with transdermal? You combine them both or completely switched to sublingual? We might be in the same situation
Estradiol valerate is more effective than Estradiol
I want to become feminine with a Norwood 0 hairline
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You both gave me new insights thanks so much! Will order EV Pills and add it to my regimen every 4 hours. Will let y'all know how it goes!
it's working insanely fast!!!
And yes.. my hair also got much darker with OM. You should also expect longer eyelashes and thicker eyebrows.. which I personally love.
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- 2,900
A guy at work told me my hair looks darker... And then said maybe its because of Winter.
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Minoxidil does something called hyperpigmentation. So I suspect it can prevent and possibly even reverse grayness to a degree. One thing I will say is that oral minoxidil improves the quality of hair better than any other drug from what I have seen. I would argue it is probably just as effective as estradiol, possibly even more so, in terms of QUALITY from what I have seen. Obviously estradiol is overall superior since it actually reverses hair loss and nearly stops it for everyone. But even those on estradiol seem to improve hair even more when they use oral minoxidil.
But I would say even finasteride is more effective than OM in terms of actual hair COUNTS, but not the quality of those hairs. So it’s very important to use combination therapy. Then there is the matter of things like topical (or oral) antiandrogens which seem to help a lot with scalp inflammation, acne, and sebum. Not only that but they attack the issue in a different way by actively down regulating the receptors, whereas 5ARIs do not have this effect and may in fact increase upregulation. What comes to mind is Derek’s advice about using multiple treatments that use varying mechanisms being generally superior to most mono therapy and potentially less sides since you can use a lower dose. For example, I would bet that 1mg finasteride + 2.5mg OM + 100mg RU or once a week 20mg topical bica is superior to 2.5mg dutasteride on its own, 10mg OM, or other mono therapies, or even a lot of dual therapies. The main exception is obviously E2 because although it would be considered monotherapy on its own it really is not only an androgen antagonist but also a growth agonist.