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He had a sort of forehead reduction surgery it wasn’t a transplant. He also was still taking aa when he left the forum- he just felt he had solved his problem and no longer wanted to spend time here.
Exploring The Hormonal Route. Hair=life.
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He had a sort of forehead reduction surgery it wasn’t a transplant. He also was still taking aa when he left the forum- he just felt he had solved his problem and no longer wanted to spend time here.
It does raise E, which can be implied due to its significant rates of gynecomastia.
Yeah, i was pretty confident it did, just had to make sure, i have the gyno to prove it does lol Thanks Ikarus
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No, it doesn't increase estradiol.
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No, it's not sweety. I have the before and after blood test report. Indeed, it decreased my estradiol.
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I have gyno too. But my estradiol level decreased after spironolactone.
Hunty, how can spironolactone cause gynecomastia if it doesn't have an effect on E? I am pretty sure it increases E... And, If it didn't then the possibility of regrowth is greatly reduced...
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Sweety, you get gyno on spironolactone because of androgen blockage. A little amount of estradiol can cause gyno, if you are on an anti-androgen.
Hunty, I am not that knowledgable on spironolactone. I believe it does increase estrogen, otherwise you would not experience regrowth from it. If it didn't increase E, then how can it lead to feminisation or other estrogenic effects?
https://www.ncbi.nlm.nih.gov/pubmed/747893
Within this study (at 300mg/day for more than 40 weeks), it states:
'In the high-dosage group, serum oestrone maintained high levels from the beginning of this study, and serum oestradiol concentrations increased with the development of gynaecomastia.'
'Thus, long-term spironolactone treatment increased the serum levels of oestrone and oestradiol in hypertensive men followed by the development of gynaecomastia. The elevation in circulating oestrogens could well explain the oestrogenic side-effects of spironolactone treatment.'
Furthermore (at 75mg to 150mg for 12 weeks), it states:
'In the conventional-dosage group, serum oestrone concentrations significantly increased (P less than 0.01) at 12 weeks, serum oestradiol concentrations gradually increased throughout the study period, however, the increments were not statistically significant (P less than 0.2).'
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spironolactone itself has some estrogenic effect, read it on wikkipedia. Because of this reason, even women experience breast enlargements while taking spironolactone.
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Waiting to arrive
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finasteride or dutasteride increases the level of temptosterone, but inhibits its conversion into dgt. I recommend only the finasteride + estradiol regimen so that the pituitary gland does not produce testosterone.
It doesn't. It's because my body is attempting to produce more T (an increase of LH can just signal that bicalutamide is working). What matters more is your actual testosterone levels (mine was 136 ng/dL when I had my blood test).
I will opt for an orchiectomy eventually... I might add more estradiol; I might increase my dose to 4mg/day.
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finasteride and dutasteride increase the level of free testosterone. Much has been written about this !!!
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that LG that FSG are working on testosterone production
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Estrogen inhibits the secretion of luteinizing hormone (LH), but not the secretion of follicle-stimulating hormone
https://www.ncbi.nlm.nih.gov/m/pubmed/3133202/