Exploring The Hormonal Route. Hair=life.

[Father_of_Shiseido]

150mg of bicalutamide is equivalent to castration in terms of an AA effect.

The AVOCAT study that compared bicalutamide 150mg + 0.5mg dutasteride found that the combination was actually more effective than castration in terms of stopping the progression of locally advanced prostate cancer.

150mg of bicalutamide is the FDA approved dose to block all AR signaling as a mono therapy drug (by itself) in men.

Your hairs should basically be good for lifetime, thats why I take this regimen.

good luck, we can be brothers , 150mg blca, 0.5mg dutas.

my only side effect is gyno, no muscle loss or ED, and also loss of depression

Loss of depression? Do you mean your depression improved on bicalutamide?

 

[KamKar]

Spironolactone gave me insomnia and cognitive decline. What to Expect from bicalutamide? Will, it also give me similar side effects?

Actually there is a similar risk for Bicalutamide too buddy.

 

[keepcoolmybabies]

Is there a drug to prevent or reduce the risk for gynecomastia?

Yes, a few, but they might mitigate the effectiveness of bica.

 

[Father_of_Shiseido]

Well lack of response can not be easily conveys to its weak uncertain agonistic effect.
Remember the case report of spironolactone-induced reversal of alopecia in an old man whose hair has started to regrow after few years of taking it, so maybe it just need more time to show its effect.
I know there are some studies showing higher efficacy of NSAAs (particularly Flutamide) in comparison with spironolactone, however NSAAs also usually have generally less favorable safety profile and higher feminizing effects in comparison with spironolactone.
Even latest guidelines regarding management of androgenic alopecia in females, suggest spironolactone as the first-line approach if there is lack of enough response to rogaine.
NSAAs may be an option when spironolactone is proven to be ineffective in a case, but generally they should not being considered before spironolactone.
Hope it helps!

I gave spironolactone 11 months.

 

[Father_of_Shiseido]

I dont have anymore depression

It means before starting bicalutamide you had depression?

 

[Father_of_Shiseido]

ye, I was balding.

Have you been on spironolactone/ cypro too? If yes, how long and why did you stop?

 

[bridgeburn]

NSAAs also usually have generally less favorable safety profile and higher feminizing effects in comparison with spironolactone.

higher feminizing effects like more hair, for example

 

[KamKar]

lmao you are literally making up stuff on the spot, NSAAs dont even lower androgen levels and actually increase them

I literally couldn't even lift the same weights back up on spironolactone/cpa, but my physique is still improving on blca

I already posted my face here too which didn't feminize at all.

Stop pulling claims without sourcing information or data.

I respect you DHTcel, but your own personal experience regarding taking this drug for only 3 months is also not considered as a reputable source to refer!
feminizing effects of these drugs are generally dose-dependent and the severity can be different case-by-case.
However as i said, generally Spironolactone is being much more studied for treating androgen-dependent skin conditions and it is still considered to be the prefered choice among systemic anti-androgens for dermatological purposes and most of the latest guidelines have consensus on this.
In men, well there is no reliable clinical evidence regarding their utility to treat androgenic alopecia and they are generally contraindicated due to feminizing effects, so basically almost no medical proffesional recommend them for treating hair loss in men.
All of the evidences are on females and the results generally can not be extended to men as well!
Anyway i am happy for your success on Bica and i wish you will stay safe and healthy on it.
Wish you the best my compariot.

 

[bridgeburn]

well there is no reliable clinical evidence regarding their utility to treat amdrogenic alopecia

We rely on anedoctal guinea pig evidence. There will never be enough proper clinical evidence anyway cause the medical industry doesn't give a sh*t if men go bald.

 

[keepcoolmybabies]

We rely on anedoctal guinea pig evidence. There will never be enough proper clinical evidence anyway cause the medical industry doesn't give a sh*t if men go bald.

I would say for now we have more anecdotal evidence around here of other regimens as bica is newer and has not been tried as frequently. But the science and studies indicate bica would be more effective.

 

[JonnyGo]

LMAO these admins permabanned my old account, my alt account AND they deleted all the photos of my regrowth from bicalutamide.

IN ADDITION, they deleted my posts on bicalutamide and how it can stop hairloss from my old account.

I will NOT be shunned, keep banning my accounts for exposing the truth that the "big 3" is a scam and that the only way to stop hairloss is by blocking testosterone. Now if you will excuse me, I'm gonna re-upload my regrowth photos, and some more photos I took last night.
View attachment 127385 View attachment 127386
View attachment 127387


my email is [email protected] AND [email protected]

email me there, also I am u/persiancel on reddit.

there are gonna keep banning my accounts because they want to make money off of their topical spironolactone and they want to hide word that bica is the cure so MAKE sure you email me so we can keep in touch.

I find it VERY fishy that they deleted ALL my posts on biclautamide and explaining that it can be a great fix for male pattern baldness in addition to my photos of hair regrowth. the left photo is me from the first day of blca and the right photo and the 2 photos above are what my hair looked like yesterday (83 days into bica).

You look better in the first picture. That hairline is way too low. Are you sure you are even balding?

 

[DinkyDino]

Have any of you who used HRT ever had burning on the hairline/area where you were losing hair that went away with taking these drugs? If so, how long after you started the regimen did it go away?

 

[Yar]

6 months, because they weren't working. I stopped them in very early June.

what to do with high testosterone for bika? I can not control the estradiol that enters my blood volume that makes bika! Why do I need high testosterone in the blood even with inactive androgen receptors?

 

[Yar]

Have any of you who used HRT ever had burning on the hairline/area where you were losing hair that went away with taking these drugs? If so, how long after you started the regimen did it go away?

yes there is a rollback when you stop accepting,

 

[I'mme]

what to do with high testosterone for bika? I can not control the estradiol that enters my blood volume that makes bika! Why do I need high testosterone in the blood even with inactive androgen receptors?

Preservation of sexual function and muscles mass. Since Bica can't completely block ARs in brain, brain recognises that body has T and continues sexual function. I don't know how these guys are gaining muscles though. @Lindsay Freeman any comments?

 

[NW3.141592]

Preservation of sexual function and muscles mass. Since Bica can't completely block ARs in brain, brain recognises that body has T and continues sexual function. I don't know how these guys are gaining muscles though. @Lindsay Freeman any comments?

DHTcel once told SAA's can't 100% stop ARs from signaling no matter what high dose is.

 

[I'mme]

DHTcel once told SAA's can't 100% stop ARs from signaling no matter what high dose is.

You don't have to stop 100% ARs from signaling because if T and DHT binding to all of them were causing us hair loss, we would have gone bald in the matter of days. A cis male may simply opt for Bica+ finasteride/dutasteride

 

[bridgeburn]

Ok, I haven't been taking min for the past several days.. I will reduce it to twice a week.
On Monday I'll pop a 10mg pill. On Friday, I'll apply topical.

 

[Stephen788]

Then why am I not responding?

Mate look at this screen shot. I asked you this question in January. You gave me this answer. You posted pictures just last week of your perfectly “recovered” hair. So you are responding. Your hair is fine.

 

[Father_of_Shiseido]

Mate look at this screen shot. I asked you this question in January. You gave me this answer. You posted pictures just last week of your perfectly “recovered” hair. So you are responding. Your hair is fine.

Mate screenshot doesn't indicate that I am not balding now. I have a few hairs with high calibre, which is giving the impression that I am not balding. The truth is that I have a lot of miniaturised hair. My density is too low, especially in the vertex area. I admit that spironolactone has improved my forelock region. But, again, my genetics is winning against spironolactone. I am balding in a pattern of my maternal uncle. Since I am suffering from male pattern baldness for the last nine years, I am in a better position to access if it is getting worse or not. You can't give judgement on my hair based on just a few snapshots. If I was delusional about my hair loss, I would have started taking spironolactone nine years back instead of find/duta. I resorted to spironolactone because thinning was obvious. My family members and friends used to say that my hairs have almost gone. You people got male pattern baldness hardly 2-3 years back and think your judgement is right about the other people. When I say spironolactone is losing the battle, it hurts you people, because AA is the only hope You people rely on. Burying your head into the sand wouldn't help. There is a fair possibility that spironolactone without estradiol wouldn't work for many.

I am almost 29, and I understand my responsibility. I wouldn't give anybody misinformation.

See my vertex, how it is creating a crater on my top.