Exploring The Hormonal Route. Hair=life.

[keepcoolmybabies]

To add, everyone's hair loss rate is different. So some people get a "mature" hairline or some temple recession and then their rate seemingly slows down dramatically regardless of treatment. Other people go completely bald in a few years after initial signs.

 

[Yar]

That's what I am trying to clarify. So unless, if you apply an anti-androgen, scalp DHT is always present even if serum DHT is normal, right? It is as if when DHT binds to androgen receptors, it doesn't go away after a period of time during which you dermarolled, massaged, applied topicals, etc.

Even though hair loss is normalized, nothing can remove scalp DHT and it is "glued" to the androgen receptors unless if you take finasteride/dutasteride, right?

What if you solely take estradiol? Is that enough to remove scalp DHT?

Thanks man for the input. Means a lot!

maybe it will take a year or two for the receptors to cease to be androgenic and become estrogenic. Otherwise, they will become shemali. Perhaps the dosage is 2 mg for the first 3 months, then 4-6. My hair stopped falling out on one estradiol.

 

[bridgeburn]

I am curious to know how anti-DHT drugs and estrogen can scientifically minimize or eliminate fibrosis along with calcification?

Women have thinner skin

 

[DinkyDino]

a lot of people here do not seem to dermaroll. do you think it's not very effective or just unnecessary?

 

[Yar]

Dermarolling alone won't do jack sh*t for regrowth. You need to combine it with potent DHT inhibitors or MX. Dr. Cots even said we as humans don't produce enough FGF 7 as mice do. FGF 7 is arguable the most important hair growth modulator. Without it, hair cannot grow.

Dermarolling doesn't upregulate FGF 7 in us humans unfortunately. Only in mice.

@bridgeburns. I know you're shy, but I think it's imperative for all of us to work together and have a Q&A session. Whoever feels comfortable in talking over the phone, I am all ears.

When we combine seasoned minds bilaterally, it only benefits us as whole in getting us one step closer to an ultimate cure. It also helps answer puzzling and pressing questions.

Guys. I am serious. I am tired in spending 8 plus years of my life reading study after study only to find out that 99% of treatments are bogus.

And most people like myself don't feel comfortable in taking the trans route. It is a very difficult decision to make to go from Male > Female.

Just something to think about and highly consider!

in fact, at the beginning of the way it seems difficult, then it starts to like!

 

[Yar]

[QUOTE = "Resurrectedhair, post: 1837694, member: 142897"] Я знаю, что я не уверен, что отвечает на мой вопрос. Что такое эстроген и анти-DHT препараты, которые удаляют фиброзную ткань и кальцифицируют наши скальпы, которые в основном находятся в кожных сосочках и наружной корневой оболочке фолликула?

Как будто эстроген, основанный на моих исследованиях, является всеобъемлющим тяжелым нападающим: он действует как пролифератор стволовых клеток, генетический пролифератор, пролифератор гормона роста, ингибитор DHT и фиброзный элиминатор.

Хммм. Массаж и ДР не нужны, чтобы показать, что происходит фиброз или кальцификация. [/ QUOTE]
вам не нужно использовать ингибиторы 5а, поскольку вы тем самым нарушаете метаболизм не только андрогенов, но и гестагенов. Метаболиты прогестерона также проходят через 5а. Если 5a ингибируется, метаболизм всех гормонов нарушается

 

[Yar]

[QUOTE = "Капоне, пост: 1837631, участник: 29953"] Что есть? [/ QUOTE]
this is estradiol, it is a dihydrotestosterone antagonist. Since both are metabolized from testosterone. When using only one estradiol, the hair stops falling out and gives growth. Estradiol is weaker than dihydrotestosterone, so either spironolactone or cpa are needed that will help estradiol to keep up! Do not use inhibitors 5a, when the inhibitor 5a is used, the metabolism of the chains is violated, including those metabolites from which estradiol should be obtained, but it is not there, that metabolite is not, because the conversion chain is broken by the inhibitor 5a.

 

[keepcoolmybabies]

[QUOTE = "Капоне, пост: 1837631, участник: 29953"] Что есть? [/ QUOTE]
this is estradiol, it is a dihydrotestosterone antagonist. Since both are metabolized from testosterone. When using only one estradiol, the hair stops falling out and gives growth. Estradiol is weaker than dihydrotestosterone, so either spironolactone or cpa are needed that will help estradiol to keep up! Do not use inhibitors 5a, when the inhibitor 5a is used, the metabolism of the chains is violated, including those metabolites from which estradiol should be obtained, but it is not there, that metabolite is not, because the conversion chain is broken by the inhibitor 5a.

Estradiol, AAs, and 5ar inhibitors all have different modes of action which I would think would be symbiotic. Not sure why you say not to use 5ar inhibitor.

 

[bridgeburn]

What is it about estrogen and anti-DHT drugs that remove fibrotic tissue and calcification from our scalps

estrogen upregulates the vitamin D receptor, perhaps that plays a role In getting calcium where it's supposed to go

 

[Mr. Grey]

What more harmful for eggs, anti androgens or estradiol?

 

[Yar]

[QUOTE = "keepcoolmybabies, post: 1837712, member: 142367"] Эстрадиол, АА и ингибиторы 5ar имеют разные способы действия, которые, я думаю, были бы симбиотическими. Не уверен, почему вы говорите не использовать 5ar ингибитор. [/ QUOTE]
metabolic mechanism violates not only androgens but also progestogens

 

[Yar]

[QUOTE = "keepcoolmybabies, post: 1837712, member: 142367"] Эстрадиол, АА и ингибиторы 5ar имеют разные способы действия, которые, я думаю, были бы симбиотическими. Не уверен, почему вы говорите не использовать 5ar ингибитор. [/ QUOTE]
найти механизм метаболизма андрогенов и прогестагенов, которые проходят через 5а

 

[Yar]

Estradiol, AAs, and 5ar inhibitors all have different modes of action which I would think would be symbiotic. Not sure why you say not to use 5ar inhibitor.

hair grows on ordinary aa and e, reddit confirms this, many asked what they used, spironolactone + e

 

[Father_of_Shiseido]

How to deal with thinning chick on spironolactone?

 

[SaitamaSensei]

The F are you talking about? This is really bad advice to give since some people are really stupid and will try everything they read online. Regimen you're describing has irreversible effects on the male body since it alters hormones on a serious level. There are plenty of people who regrew their hair even on finasteride 1mg and minoxidil alone. It all comes down to how you respond to drugs. Most people on this forum want to regrew their hair to appeal to girls and look their best. If you have hair but cant perform in bed than whats the point of putting your liver in such stress and risking to have diseases later in life.

[QUOTE = "resurrectedhair, post: 1837586, member: 142897"] Мне всегда было интересно, когда DHT связывается с рецепторами волос, что происходит с DHT кожи головы ?

Разве скальп DHT не исчезнет, пока вы не примените антиандроген?

Признаки того , что DHT в коже головы отсутствует, если есть предположения, что у людей есть проблемы с возобновлением роста волос?

Это потому, что они не нашли правильные формулы для стимулирования цикла отрастания? Или это потому, что DHT скальпа все еще Присутствует, а «правильные» формулы специально не предназначены для устранения препятствий - то есть, сначала удаляют скальп DHT?

Причина, по которой я задаю эту провоцирующую мысль, заключается в том, что я попробовал буквально все в Руководстве по андрогенной алопеции, кроме антиандрогенов. (в том числе среди дермароллингов, штамповок, топиков, масел и т. д.). Казалось, ничего не работает, как ожидалось.

Чтобы избавиться от волос, нужно сначала удалить DHT кожи головы .

Я открыт для любых исправлений!

Большое спасибо за любой вклад в звук! [/ QUOTE]
[QUOTE = "resurrectedhair, post: 1837586, member: 142897"] Мне всегда было интересно, когда DHT связывается с рецепторами андрогенов и вы замечаете, что выпадение волос нормализуется, что происходит с DHT кожи головы ?

Разве скальп DHT не исчезнет, пока вы не примените антиандроген?

Признаки того , что DHT в коже головы отсутствует , если есть предположения, что у людей есть проблемы с возобновлением роста волос ?

Это потому, что они не нашли правильные формулы для стимулирования цикла отрастания? Или это потому, что DHT скальпа все еще Присутствует, а «правильные» формулы специально не предназначены для устранения препятствий - то есть, сначала удаляют скальп DHT?

Причина, по которой я задаю эту провоцирующую мысль, заключается в том, что я попробовал буквально все в Руководстве по андрогенной алопеции, кроме антиандрогенов. (в том числе среди дермароллингов, штамповок, топиков, масел и т. д.). Казалось, ничего не работает, как ожидалось.

Чтобы избавиться от волос, нужно сначала удалить DHT кожи головы .

Я открыт для любых исправлений!
to prevent further baldness, you need to switch to a trans mode, no more. Taking normal aa and e together. It can be spironolactone 50-100-200mg or cypro 12-25-50mg. Estradiol starting from 2mg further 4-6-8-12mg. Then you kind of start to recode your body to aromatase. And it all starts on the female type. There are no more ways. Neither finasteride nor dutasteride are able to grow hair, you start to have a female type haircut with a feminine appearance and feminine, thighs, fat distribution, chest, lack of body hair, smooth skin, lack of s masculine smell sh*t! My feet are at the moment on the female type.

 

[Derelict]

The F are you talking about? This is really bad advice to give since some people are really stupid and will try everything they read online. Regimen you're describing has irreversible effects on the male body since it alters hormones on a serious level. There are plenty of people who regrew their hair even on finasteride 1mg and minoxidil alone. It all comes down to how you respond to drugs. Most people on this forum want to regrew their hair to appeal to girls and look their best. If you have hair but cant perform in bed than whats the point of putting your liver in such stress and risking to have diseases later in life.

This thread is about aggressive hormonal treatments for hair loss, makes sense people would be talking about estradiol etc If you don't like it no one is forcing you to read it.

 

[Mr. Grey]

What about balls? What more damages eggs, aa or estro???

 

[Mr. Grey]

Can you safe hair with only estro? Example 2 mg per day. Yes, i assumes to take 0,5 duta every day

 

[Mr. Grey]

I have some maintenance with 2 mg estro+12,5 cpa+0,5 duta. My balls was damaged. I refused from cpa.

 

[Yar]

The F are you talking about? This is really bad advice to give since some people are really stupid and will try everything they read online. Regimen you're describing has irreversible effects on the male body since it alters hormones on a serious level. There are plenty of people who regrew their hair even on finasteride 1mg and minoxidil alone. It all comes down to how you respond to drugs. Most people on this forum want to regrew their hair to appeal to girls and look their best. If you have hair but cant perform in bed than whats the point of putting your liver in such stress and risking to have diseases later in life.

finasteride and dutasteride is sh*t! After finasteride, a terrible hair fall started! After cpa and e there is nothing like that, everything grew stronger and grew.