Exploring The Hormonal Route. Hair=life.

[I'mme]

Igf-1, hmmm

"Men with higher levels of testosterone were more likely to have vertex baldness (odds ratio [OR] = 2.5, 95% confidence interval [CI: 0.9 to 7.8] per 194 ng/dL increment of testosterone). In addition, for each 59 ng/mL increase in IGF-1, the odds of having vertex baldness doubled (95% CI [1.0 to 4.6]). Those who were found to have higher circulating levels of SHBG were less likely to have dense hair on their chest (OR = 0.4, 95% CI [0.1 to 0.9] per 24 nmol/L increment in SHBG])."

Dropped Mk677 as I was scared.

 

[Father_of_Shiseido]

Dropped Mk677 as I was scared.

Did you see any regrowth on spironolactone?

 

[I'mme]

Did you see any regrowth on spironolactone?

If there is, it is not noticeable yet. I'm not taking it for a week now tho, since raloxifene is not available and tamox also seems to be going out of stock.

Maybe I should be happy with no further hair loss and continue waiting.

I'm interested in Cyproterone Acetate but it is also not available in India and I don't have payments methods that inhousepharmacy asks for.

 

[Peace]

If there is, it is not noticeable yet. I'm not taking it for a week now tho, since raloxifene is not available and tamox also seems to be going out of stock.

Maybe I should be happy with no further hair loss and continue waiting.

I'm interested in Cyproterone Acetate but it is also not available in India and I don't have payments methods that inhousepharmacy asks for.

I think it will be fatal

 

[I'mme]

I think it will be fatal

What will be fatal?

 

[Father_of_Shiseido]

If there is, it is not noticeable yet. I'm not taking it for a week now tho, since raloxifene is not available and tamox also seems to be going out of stock.

Maybe I should be happy with no further hair loss and continue waiting.

I'm interested in Cyproterone Acetate but it is also not available in India and I don't have payments methods that inhousepharmacy asks for.

Ralox is available on 1mg.com. You will never be able to import medicines from the in-house pharmacy, and the customs department might impose a heavy penalty on you.

 

[Jonny Craig]

there's less Dht in your balls

Oh, lol yeah.. thought he was asking about sides though.

 

[bridgeburn]

Oh, lol yeah.. thought he was asking about sides though.

Are there any studies about P on the balls?

 

[I'mme]

Ralox is available on 1mg.com. You will never be able to import medicines from the in-house pharmacy, and the customs department might impose a heavy penalty on you.

It isn't available in any online app. They may be showing it there in your area but once you order they'll tell you that there's no stock of it.

 

[Jonny Craig]

Are there any studies about P on the balls?

In his book, "What Your Doctor May Not Tell You About Prostate Health and Natural Hormone Supplementation", Dr. John Lee writes that in the prostate (and in the hair follicles) is an enzyme (5-alpha-reductase) that converts testosterone into dihydrotestosterone (DHT). Higher DHT levels in hair follicles is a primary cause of male pattern baldness. He states that DHT stimulates proliferation of prostate cells enlarging the prostate gland and narrowing the urethral channel, leading to urination problems, and speculation that elevated DHT is the cause of prostate cancer.

Since progesterone is a potent inhibitor of 5-alpha-reductase, the decline of progesterone in aging males plays a role in increasing the conversion rate of testosterone to DHT. Supplementing with progesterone cream helps restore normal inhibition of 5-alpha-reductase, thus preventing testosterone from changing into dihydrotestosterone (DHT), which stimulates proliferation of prostate cells. Dr. Lee suggests that men over the age of 40 use 8 - 12 mg of natural progesterone applied directly to their scrotum twice daily every day of the week to protect against prostate cancer.

Not sure how accurate all of these studies are, but:

At the Institute for Biological Medical Experiments in Buenos Aires it was shown progesterone shrank prostate weight in test animals as well as reduced 5-alpha reductase activity.

At Central Hospital University in Paris progesterone was shown to inhibit the formation of DHT as well as binding of it to the prostate. DHT content in the prostate is the single most causative factor in prostate disease.

At the Biochemical Medical Laboratory in France the doctors demonstrated in human BPH tissue there are more progesterone receptors which show how responsive the prostate is to this hormone.

At the Institute of Clinical Chemistry in Bochum, Germany progesterone in human BPH tissue reduced the activity of 5-alpha reductase strongly.

 

[bridgeburn]

At the Institute for Biological Medical Experiments in Buenos Aires it was shown progesterone shrank prostate weight in test animals as well as reduced 5-alpha reductase activity.

At Central Hospital University in Paris progesterone was shown to inhibit the formation of DHT as well as binding of it to the prostate. DHT content in the prostate is the single most causative factor in prostate disease.

At the Biochemical Medical Laboratory in France the doctors demonstrated in human BPH tissue there are more progesterone receptors which show how responsive the prostate is to this hormone.

At the Institute of Clinical Chemistry in Bochum, Germany progesterone in human BPH tissue reduced the activity of 5-alpha reductase strongly.

I wonder if more reaches the prostate through rectal administration... Hmm

 

[bridgeburn]

Jok3r aka ObsoleteTinker is not only banned but Super banned ( all his posts are deleted) lol

 

[yourworld001]

Can someone please send me a invite to the discord group, recently started Estrogel so would like to see how others are getting on...

 

[baldingAF]

@bridgeburn
https://www.ncbi.nlm.nih.gov/pubmed/30817981

For another possible buffer for the aromatase angle, but is it safe. The more promising of the list was the following two:

• n-butylparaben - https://onlinelibrary.wiley.com/doi/abs/10.1002/bdrb.20153
• benzophenone-2: http://sci-hub.tw/10.1016/j.mce.2019.02.016 , https://www.ncbi.nlm.nih.gov/pubmed/30817981

But still safety. It seems a lot of things in this real that increase these factors are seemingly harmful.

 

[keepcoolmybabies]

In his book, "What Your Doctor May Not Tell You About Prostate Health and Natural Hormone Supplementation", Dr. John Lee writes that in the prostate (and in the hair follicles) is an enzyme (5-alpha-reductase) that converts testosterone into dihydrotestosterone (DHT). Higher DHT levels in hair follicles is a primary cause of male pattern baldness. He states that DHT stimulates proliferation of prostate cells enlarging the prostate gland and narrowing the urethral channel, leading to urination problems, and speculation that elevated DHT is the cause of prostate cancer.

Since progesterone is a potent inhibitor of 5-alpha-reductase, the decline of progesterone in aging males plays a role in increasing the conversion rate of testosterone to DHT. Supplementing with progesterone cream helps restore normal inhibition of 5-alpha-reductase, thus preventing testosterone from changing into dihydrotestosterone (DHT), which stimulates proliferation of prostate cells. Dr. Lee suggests that men over the age of 40 use 8 - 12 mg of natural progesterone applied directly to their scrotum twice daily every day of the week to protect against prostate cancer.

Not sure how accurate all of these studies are, but:

At the Institute for Biological Medical Experiments in Buenos Aires it was shown progesterone shrank prostate weight in test animals as well as reduced 5-alpha reductase activity.

At Central Hospital University in Paris progesterone was shown to inhibit the formation of DHT as well as binding of it to the prostate. DHT content in the prostate is the single most causative factor in prostate disease.

At the Biochemical Medical Laboratory in France the doctors demonstrated in human BPH tissue there are more progesterone receptors which show how responsive the prostate is to this hormone.

At the Institute of Clinical Chemistry in Bochum, Germany progesterone in human BPH tissue reduced the activity of 5-alpha reductase strongly.

I'm probably going to start taking progesterone soon as it can be a very potent AA due to it's gonadotropin effects. Particularly if you have high enough circulating progesterone, it's able to overstimulate your pituitary causing it to signal your body to stop producing testosterone. Then you can reprogram your endocrine system. Granted if you still want T, it's not the way to go. But for those on strong AA's it might be a more viable (and potentially healthier long term) option.

 

[E-nC]

Can someone recommend me an estrogen that's effective, but wont harm me?

 

[E-nC]

estrofem/Oestrogel

I can get it in a topical right?

 

[LEXUS]

Oestrogel is transdermal

you did not answer me. Are you still taking avodart? I accept so far. Dutasteride first gives a strong barn. You can even completely bald. but then. a miracle happens. a real miracle. Together with cyproterone and spironolactone Avodart is a very powerful tool. do you accept avodart

 

[Obsessive]

you did not answer me. Are you still taking avodart? I accept so far. Dutasteride first gives a strong barn. You can even completely bald. but then. a miracle happens. a real miracle. Together with cyproterone and spironolactone Avodart is a very powerful tool. do you accept avodart

Well, I experienced the part where dutasteride was turning me to Mr Clean really fast. Not the look I'm going for. After 4 months I'd seen enough and dropped it. I have a hard time understanding why one needs to go bald before the regrowth starts with any drug

 

[LEXUS]

Well, I experienced the part where dutasteride was turning me to Mr Clean really fast. Not the look I'm going for. After 4 months I'd seen enough and dropped it. I have a hard time understanding why one needs to go bald before the regrowth starts with any drug

It’s also hard for me to understand. maybe the hair that grows from antiandrogens is completely different. they even have a different structure. another cycle. and everything else. what grew from testosterone falls out. I do not know.