Exploring The Hormonal Route. Hair=life.

Ikarus

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What is a powerful antiandrogen that won't cause gyno? is there one? I can accept everything else (lower libido, ED, feminization, etc..)

CPA. Theoretically, combining CPA and bicalutamide could prevent gynecomastia...
 

Derelict

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CPA. Theoretically, combining CPA and bicalutamide could prevent gynecomastia...

Im not well read on CPA but doesn't it have a risk of benign tumors or something along those lines? As for bica, are you still ordering it online or has a derm prescribed it to you yet? How is your derm? im sort of dreading the day i go and tell my GP what i have been taking for hair loss, especially since my last GP stopped working and the one i have now is a bit of an arse, wouldn't even prescribe me finasteride when i asked. lol
 

Harv

Established Member
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im on finasteride and dutasteride.
its well known that fina raises T and E by 15%.
Anyways im not getting regrowth, just lost alot of hairs.
My estrogen serum is 139nmol -do they need to be increased with taking E too see if it will help with regrowth or is 139 a good amount?
 

Jordaniel

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I think my goal now is to try and just increase aromatase (promoter i.4) for adipose conversion of T into E and hope that stays local and I can sort of create a trap to make sure that area keeps DHT?T low but with higher E. There are a few studies saying there is depletion of aromatase in the common balding areas in ADA so maybe thats it. I'll try and keep everyone posted.

If anyone knows anything that increases aromatase (other than Dex, EP1 & EP2 agonists, PGE2 & PGE1) let me know!

Yo holy sh*t wait, so high E (low t) should decrease aromatase activation in the scalp? Bro that is news to me. I have estrogen pills. Might just supplement some and see what happens.
 

Ikarus

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Im not well read on CPA but doesn't it have a risk of benign tumors or something along those lines? As for bica, are you still ordering it online or has a derm prescribed it to you yet? How is your derm? im sort of dreading the day i go and tell my GP what i have been taking for hair loss, especially since my last GP stopped working and the one i have now is a bit of an arse, wouldn't even prescribe me finasteride when i asked. lol

If you're using CPA at doses of 6.25mg/day, I would say that the risks are rather minimal. I am still ordering bicalutamide online, I have to wait almost two years to be prescribed bicalutamide so it's best for me to continue ordering it. If you tell your GP what you are taking, just say you are non-binary and that you want to be referred to a gender specialist and see what they say.
 

Sanchez1234

Experienced Member
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311
Guys, im here because im using 1mg dutasteride for 8 months now and oh flut. My hair shedding is the same and lost atleast a norwood and its the the regrow after shedding type. Hair thinnes out all over as well.

Whats next? Anybody here succesfully maintained while dutasteride alone was not enough?
Anybody doing the hormonal right and still has some dick function?
 

LEXUS

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if you want dutasteride to work without anything, take 5 capsules. You can take less if you use HRT, but for hair the most important component of dutasteride, without it it will be difficult and long, maybe in vain. the most harmful of all this is cyproterone, it is anti-estrogenic too. more than 1 mg I will never take again.
 

keepcoolmybabies

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Anybody doing the hormonal right and still has some dick function?
Kinda loaded question. You will probably still be able to get erections (I haven't had an issue), but your libido might be shot so you won't care much to use it. Also you obviously won't be fertile.
 

Ikarus

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CPA = cyproterone acetate, correct? What dosage should I start with? and for how long?

Correct. If you’re going to use an AA, stick with it permanently. I would say to start with 50mg/day of CPA for a month then cut the dose down to 25mg/day, and then see how things go from there. If you’re going to combine it with bicalutamide, use 50mg/day of bicalutamide along with 6.25mg/day of CPA. I find the second option the safest in the long term, but that combination not causing obvious gyno is theoretical.
 

Sanchez1234

Experienced Member
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Kinda loaded question. You will probably still be able to get erections (I haven't had an issue), but your libido might be shot so you won't care much to use it. Also you obviously won't be fertile.

Correct. If you’re going to use an AA, stick with it permanently. I would say to start with 50mg/day of CPA for a month then cut the dose down to 25mg/day, and then see how things go from there. If you’re going to combine it with bicalutamide, use 50mg/day of bicalutamide along with 6.25mg/day of CPA. I find the second option the safest in the long term, but that combination not causing obvious gyno is theoretical.

Thanks for responding. On 1mg dutasteride i can get erection but loss of libido is severe. And i want children in the future.

Is the combi mentioned stronger then dutasteride? @Ikarus

Maybe i am hoping for someone who still can have sex when needed, has a child wish and is on a hardcore regime stronger than dutasteride..
 

keepcoolmybabies

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Thanks for responding. On 1mg dutasteride i can get erection but loss of libido is severe. And i want children in the future.

Is the combi mentioned stronger then dutasteride? @Ikarus

Maybe i am hoping for someone who still can have sex when needed, has a child wish and is on a hardcore regime stronger than dutasteride..
if you want kids, i'd definitely freeze some sperm just in case.
 

Brenna

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Has anyone tried just estrogen and no inhibitors?

Wouldn't work unless you do monotherapy via injections, and those are something that you can't do half measures on; they are designed to turn you into a woman.
 

Tattoo

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That kind of defeats the purpose IMO. If you want to cycle it then yeah.
Only blocks e on the breast tissue. I thought on going on it once I can save enough. It’s expensive at 80$ a month here in Canada.
 

StevenGerrard

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Leo Sheng is a female to male trans actor.. anyway.. watch the clip, he is clearly balding from all the T injections and whatnot :(
 
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