Exploring The Hormonal Route. Hair=life.

[hahahamyhairisdead]

Dude, most interesting and pity’s that they finally will lose hair and destroyed health.

That's their problem, not your. Maybe they want to be a woman.
But I understand your position, because I tried bicalutamide and dropped it after 2 months because I'm not prepared for the consequences.

 

[baldingAF]

I'm going to answer your question in 2 parts:

1) yes men get most of their E2 from aromatase, testosterone is an E2 precursor.

2) aromatase does the opposite of contributing to AA, rather the correlation I was referring to is that the areas of the scalp which are deficient in aromatase tend to be the same areas prone to baldness (especially the temples). In women for example the frontotemporal region of the scalp tends to have around 600% the amount of aromatase as it does in men and that is part of the reason the temples are often spared in women with FPB even though men with low T still lose their temple hair sometimes. You see, even with low T if E2/aromatase are low then you can still have high site specific androgen signalling in the scalp follicles due to paracrine activity via 5AR enzymes when there isn't cyp19a to siphon off the testosterone in situ, most prominently in the temples and crown (typical male pattern baldness areas).

Can you send me any/all of your aromatase research or at least the more prominent ones? agonists? cancer/damage increasing aromatase? I am about to start treatment and I want to have anything I may have overlooked

 

[Ikarus]

Dude, most interesting and pity’s that they finally will lose hair and destroyed health.

No sex, no hair, no health, no men

Ok!

 

[Gergely]

I'm starting to worry, my hair is falling out like crazy. Is that normal on spironolactone and estradiol?

 

[keepcoolmybabies]

I'm starting to worry, my hair is falling out like crazy. Is that normal on spironolactone and estradiol?

What's your dosage and how long have you been on it?

 

[Gergely]

What's your dosage and how long have you been on it?

22 days total 100mg spironolactone after day 19 200mg. 20 days on 2mg estradiol under the tongue

 

[keepcoolmybabies]

22 days total 100mg spironolactone after day 19 200mg. 20 days on 2mg estradiol under the tongue

Definitely not enough time to gauge what to attribute the shedding to. There's the possibility that, as with many hair loss treatments, it's a shed preceding regrowth. Or there's also a decent chance that you triggered Telogen Effluvium, which can happen anytime you throw your hormones off their typical cycle. If it's indeed Telogen Effluvium the hair should grow back in several months assuming your levels stay consistent.

Id reassess how your shedding is at 3 months and then hopefully you begin to see growth by 6 months.

 

[Gergely]

Well, that is depressing. Thank you for your quick answer
Edit: Once i triggered it, it's a done deal right? doesn't matter what i do

 

[Mr. Grey]

Well, that is depressing. Thank you for your quick answer
Edit: Once i triggered it, it's a done deal right? doesn't matter what i do

You have to wait couple of months, you early took 200 mg, 100 will work perfect. With spironolactone you don’t need estro. Take pity your eggs and dick, not entrance in castrates club. You also need use scalp massage, you can find this topic on this forum (alternative methods)

 

[Ikarus]

I'm starting to worry, my hair is falling out like crazy. Is that normal on spironolactone and estradiol?

Yes. When I started spironolactone and estradiol, I got that too. It’s due to a hormonal shift, it definitely won’t be bad though.

You have to wait couple of months, you early took 200 mg, 100 will work perfect. With spironolactone you don’t need estro. Take pity your eggs and dick, not entrance in castrates club. You also need use scalp massage, you can find this topic on this forum (alternative methods)

Take pity to your scalp massages

 

[bridgeburn]

Collagen

 

[Derelict]

Collagen

View attachment 133864

I have been taking collagen and hyaluronic acid supplements for quite a while, can't hurt. I just take 2g a day of collagen and 200mg hyaluronic.

 

[Ikarus]

Those don’t do anything at all. It’s like taking bcaas to gain muscle.

It’s for skin benefits

 

[fugged]

Jesus bridgeburn sorry I'm late to the party, absorbing this but how is your hair and your health? I was considering topical soy isoflavones, but a bit nervous. I cant believe the gains you made.

 

[KobayashiYuuta]

so this may be considered to be normal 'estradiol shedding'? i'm just on spironolactone 100-150mg and estradiol 1mg a day (i think this is a very small dose) for about a month, shedding is increasing... i'm thinking about adding yasmin to my regimen, is this necessary? also, my gyno occured with this dose but i'm enjoying with it

 

[Ikarus]

so this may be considered to be normal 'estradiol shedding'? i'm just on spironolactone 100-150mg and estradiol 1mg a day (i think this is a very small dose) for about a month, shedding is increasing... i'm thinking about adding yasmin to my regimen, is this necessary? also, my gyno occured with this dose but i'm enjoying with it

It is normal, but maybe you should switch our Spironolactone for another anti-androgen?

 

[Salvador Adam Llopis]

anyone knows anything about exosomes?
this article is interesting:

https://www.ncbi.nlm.nih.gov/pubmed/30924959

 

[Gergely]

Weird question, is it "normal" for gyno to occur on the less prominent side sooner?

 

[KobayashiYuuta]

It is normal, but maybe you should switch our Spironolactone for another anti-androgen?

i asked my dr. for cpa and bica but he refused. he said my current regimen is crazy and the limit lol. i can't get these from online overseas pharmacy in my country either due to the strict laws, or would be confiscated by the custom. spironolactone is the only one i can get. so sad.

 

[Derelict]

i asked my dr. for cpa and bica but he refused. he said my current regimen is crazy and the limit lol. i can't get these from online overseas pharmacy in my country either due to the strict laws, or would be confiscated by the custom. spironolactone is the only one i can get. so sad.

That sucks, where are you from if i may ask?