Exploring The Hormonal Route. Hair=life.

Blackweasel

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I think it’s weird because anyone using it disappeared and never spoke of their results again

Ikarus, I see you are knowledgeable on Bicalutamide. I have chosen to give my current regimen 3 more months to assess for progress.

If that doesnt happen next step is to add Bica and RU58841. What dosage would you suggest for Bica for someone wanting hair but minimal feminine side effects? I also want results by end of year if ofcourse possible so need some bang too.
Am already on dutasteride, topical spironolactone minoxidil etc
 

NorwoodingMyWay

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Ikarus, I see you are knowledgeable on Bicalutamide. I have chosen to give my current regimen 3 more months to assess for progress.

If that doesnt happen next step is to add Bica and RU58841. What dosage would you suggest for Bica for someone wanting hair but minimal feminine side effects? I also want results by end of year if ofcourse possible so need some bang too.
Am already on dutasteride, topical spironolactone minoxidil etc
The thing with Bica is its very high gyno chances at recommended doses of 50mg-100mg. Mixing both RU and Bica is pointless since Bica does everything RU does but better and it's actually a documented drug unlike RU (smearing untested chemical compounds from china is questionable at least). Plus, administrating Bica will raise your T levels 2 folds, so it may or may not block all of it at the recommended doses.





About topical spironolactone, it's pretty much pointless. Spironolactone needs to be metabolised in the liver into its active forms to produce its effects. Topical application mostly inhibits this metabolism and the very little that makes it into the blood is negligible to do anything. Dutasteride and minoxidil are very good for the majority, unless you started balding in your teens.
 

Blackweasel

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The thing with Bica is its very high gyno chances at recommended doses of 50mg-100mg. Mixing both RU and Bica is pointless since Bica does everything RU does but better and it's actually a documented drug unlike RU (smearing untested chemical compounds from china is questionable at least). Plus, administrating Bica will raise your T levels 2 folds, so it may or may not block all of it at the recommended doses.





About topical spironolactone, it's pretty much pointless. Spironolactone needs to be metabolised in the liver into its active forms to produce its effects. Topical application mostly inhibits this metabolism and the very little that makes it into the blood is negligible to do anything. Dutasteride and minoxidil are very good for the majority, unless you started balding in your teens.

Im a ‘special’ case as I started balding at 17 due to anabolic steroid use. All males in my family are NW5-7 and nobody makes it past 30 with hair.
If Bicalutamide inscreases testosterone (as does dutasteride) then how does it help regrow hair? I will be cycling raloxifene to combat gyno and may opt for surgery down the line. When I use topical spironolactone this is after dermarolling, maybe this will have more effect?
 

Father_of_Shiseido

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Im a ‘special’ case as I started balding at 17 due to anabolic steroid use. All males in my family are NW5-7 and nobody makes it past 30 with hair.
If Bicalutamide inscreases testosterone (as does dutasteride) then how does it help regrow hair? I will be cycling raloxifene to combat gyno and may opt for surgery down the line. When I use topical spironolactone this is after dermarolling, maybe this will have more effect?
Bicalutamide will stop the progression of your hair loss at a dose of 50 my, but the increase in testosterone is followed by an increase in estradiol and therefore you will lose most of your masculine trait. You can try it but I think you would not be able to take it for a full year.
 

Blackweasel

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Bicalutamide will stop the progression of your hair loss at a dose of 50 my, but the increase in testosterone is followed by an increase in estradiol and therefore you will lose most of your masculine trait. You can try it but I think you would not be able to take it for a full year.
Is there any point trying 30mg every second day? I already have low DHT with dutasteride but have high testosterone which is stopping regrowth and possibly attacking my follicles.
I would need an Anti androgen to reduce test but really want to try all else before oral spironolactone or cypro, I want to half my testosterone but not eradicate it.
 

Father_of_Shiseido

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Is there any point trying 30mg every second day? I already have low DHT with dutasteride but have high testosterone which is stopping regrowth and possibly attacking my follicles.
I would need an Anti androgen to reduce test but really want to try all else before oral spironolactone or cypro, I want to half my testosterone but not eradicate it.
Bicalutamide at 25 mg should do the trick for you, but it is highly feminising. For eg. you can read this Anecdotal report
https://docs.google.com/document/u/0/d/1PYWaZaHazpbyOtGEWIq4krsVmqLxENIhFqJW4fBuXv8/mobilebasic
 

Blackweasel

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Bicalutamide at 25 mg should do the trick for you, but it is highly feminising. For eg. you can read this Anecdotal report
https://docs.google.com/document/u/0/d/1PYWaZaHazpbyOtGEWIq4krsVmqLxENIhFqJW4fBuXv8/mobilebasic

Thanks for the link! I have read through it.... it seems that Bic and finasteride were really increasing testosterone for him which would be a problem for my hair. My testosterone is naturally very high and ive suffered from acne and hair loss for a long time, its even higher now with dutasteride and am getting more acne.
I may need to micro dose on cypro even like 6mg 2x per week, im just afraid Bicalutamide is going to further increase testosterone. Ill also be on Raloxifene to try and limit gyno whilst I save up for surgery to remove glands altogether if i get it.
Its gonna be quite the journey... f$&@ng hair..
 

Father_of_Shiseido

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Thanks for the link! I have read through it.... it seems that Bic and finasteride were really increasing testosterone for him which would be a problem for my hair. My testosterone is naturally very high and ive suffered from acne and hair loss for a long time, its even higher now with dutasteride and am getting more acne.
I may need to micro dose on cypro even like 6mg 2x per week, im just afraid Bicalutamide is going to further increase testosterone. Ill also be on Raloxifene to try and limit gyno whilst I save up for surgery to remove glands altogether if i get it.
Its gonna be quite the journey... f$&@ng hair..
50 mg bica would block most of the test, but the real danger is significant feminisation. Didn't you notice it in that guy in the link?
 

Blackweasel

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50 mg bica would block most of the test, but the real danger is significant feminisation. Didn't you notice it in that guy in the link?

I did but he was more feminine than I am to begin with. I am basically too masculin, well defined body, extremely thick facial hair, Androgenetic Alopecia, rough skin+ acne ,hirsutism and excessive body hair... I think this can benefit me to be honest. I naturally have too much test. I would also take smaller dose than he did as im only after hair restoration in mid scalp and crown. My only question is will Bica+ dutasteride cause higher test and more problems since it doubles it like it did to him? Will I need cypro or can I go without? @Father_of_Shiseido thanks for your help by the way. Its hard to figure all this out without experience. I will research Bica fuether.
 

Ikarus

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Ikarus, I see you are knowledgeable on Bicalutamide. I have chosen to give my current regimen 3 more months to assess for progress.

If that doesnt happen next step is to add Bica and RU58841. What dosage would you suggest for Bica for someone wanting hair but minimal feminine side effects? I also want results by end of year if ofcourse possible so need some bang too.
Am already on dutasteride, topical spironolactone minoxidil etc

With your age, you won't experience much 'feminisation' from bicalutamide at the doses of 50mg/day, but you will produce gynecomastia and will appear demasculinised nonetheless, and the gynecomastia is certain even with low doses. I think you should just combine dutasteride and oral minoxidil, and see how that goes.
 

Blackweasel

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With your age, you won't experience much 'feminisation' from bicalutamide at the doses of 50mg/day, but you will produce gynecomastia and will appear demasculinised nonetheless, and the gynecomastia is certain even with low doses. I think you should just combine dutasteride and oral minoxidil, and see how that goes.
Ill give oral minoxidl and dutasteride etc some more months and assess from there. Thanks for your feedback :)
 

Father_of_Shiseido

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I did but he was more feminine than I am to begin with. I am basically too masculin, well defined body, extremely thick facial hair, Androgenetic Alopecia, rough skin+ acne ,hirsutism and excessive body hair... I think this can benefit me to be honest. I naturally have too much test. I would also take smaller dose than he did as im only after hair restoration in mid scalp and crown. My only question is will Bica+ dutasteride cause higher test and more problems since it doubles it like it did to him? Will I need cypro or can I go without? @Father_of_Shiseido thanks for your help by the way. Its hard to figure all this out without experience. I will research Bica fuether.
Even if bica increases your test level it will still be blocked. Don’t worry but keep watching for facial feminization.
 

Deacr4

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Hey guys, first found this thread a few years ago and found out about how hormones play such a role in hair loss. Amazed at the continued results a lot of you are getting ^^

I first really noticed hair loss around 19 but it must have started at 16/17, mainly lost hair around the temples and a little thinner generally on top but it's not so bad. I've started taking Bica 50mg for a couple of months now as well as Fina, what are the chances of getting regrowth with this combo? I'm about a 2 or 3 on the norwood scale. Thinking about adding in 2mg Estradiol as well :) I don't mind all of the side effects haha, some I welcome tbh. I'll have to get my sperm frozen first though.

Anyway thanks for the inspiration, I feel lucky to be born at a time where this is possible and there's all this info on the net, yet unlucky to have lost hair so young :confused: haha
 
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Father_of_Shiseido

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Hey guys, first found this thread a few years ago and found out about how hormones play such a role in hair loss. Amazed at the continued results a lot of you are getting ^^

I first really noticed hair loss around 19 but it must have started at 16/17, mainly lost hair around the temples and a little thinner generally on top but it's not so bad. I've started taking Bica 50mg for a couple of months now as well as Fina, what are the chances of getting regrowth with this combo? I'm about a 2 or 3 on the norwood scale. Thinking about adding in 2mg Estradiol as well :) I don't mind all of the side effects haha, some I welcome tbh. I'll have to get my sperm frozen first though.

Anyway thanks for the inspiration, I feel lucky to be born at a time where this is possible and there's all this info on the net, yet unlucky to have lost hair so young :confused: haha
What side effects do you have on bicalutamide?
 

Kaue carrera

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With your age, you won't experience much 'feminisation' from bicalutamide at the doses of 50mg/day, but you will produce gynecomastia and will appear demasculinised nonetheless, and the gynecomastia is certain even with low doses. I think you should just combine dutasteride and oral minoxidil, and see how that goes.


Ikarus

For people who take finasteride once a day

Does adding Dutasteride once a week make any sense?
 

baldingAF

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What is the active form of spironolatone? Is it something that can be applied topically?

dang bica sounds good besides the gyno. Is that the only negative side? Also has anyone had regrowth on bica WITHOUT some additional E2?

I need a solid agent for the androgen receptor and I’ll be good for a few months as I think what I have covers the other angles.
 

Ikarus

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Ikarus

For people who take finasteride once a day

Does adding Dutasteride once a week make any sense?

In my opinion, no, since dutasteride has to build up in your body to reach its effect. It will build up with that weekly dosage, but it’d take much longer.
 
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