- Reaction score
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My guess is at 25mg of CPA, Bica won't have much left behind to raise. So T will be lower. Then Bica won't let them bind to AR.
Are u still using estrogen ? I have been on bica for months now and all i could gain is gyno and weight.Seems like really not doing anything without minoxidil or estrogen. What a disappointment.
So basicaly oral minoxidil, CPA, E and Duta + castration
My guess is at 25mg of CPA, Bica won't have much left behind to raise. So T will be lower. Then Bica won't let them bind to AR.
One question, my next regimen will be cyproterone, but I don't want to use high doses just 25 mg a day, I would like to combine it with flutsmide or bicalutamide.
My question is, will blood testosterone drop or rise?
cyproteone decreases lh but bica increases testosterone by positive feedback.
There's actually an old case study of a man who got strong regrowth with spironolactone monotherapy. That just shows that spironolactone is more than just an AA.
Nobody's fault that your taking for granted "medical advise" from insecure, retarded and mentally ill kids from a hairloss forum. We and me personally have posted tons of information about this drug, all being ignored and downplayed by the bunch of retarded fucks who think they are doctors or some kind of scientists from their mothers basements after reading some studies and anecdotal reports...
Unfortunately you can't guard and warn all the people who visit these forums about it's dangers, meaning the mentally ill fucks who are castrating themselves and after saying that they are still males or perfectly healthy and so on and that encourage others to go on their route. I'm sorry for your experience but in the same time you kind of deserve it for trusting blindly a bunch of unknown retards from a hairloss forum...
And, I’d like to say that bicalutamide *is* a magical pill when compared with other AAs.
@bridgeburn got regrowth with cpa at higher doses and Estradiol. And I don't reckon him using spironolactone at anytime.There's actually an old case study of a man who got strong regrowth with spironolactone monotherapy. That just shows that spironolactone is more than just an AA.
@bridgeburn got regrowth with cpa at higher doses and Estradiol. And I don't reckon him using spironolactone at anytime.
He was taking 100mg spironolactone i believe.
Didn't someone say they got better results on duta+spironolactone than duta+bica, i think bica is better if you are taking E maybe, but if not spironolactone may be the better option.
@bridgeburn got regrowth with cpa at higher doses and Estradiol. And I don't reckon him using spironolactone at anytime.
Can you confirm this? A quick search for @bridgeburn and spironolactone returns his negative comments on the drug. I reread the first page of this post and no mention of spironolactone too just high level of CPA.
Beside why would he be using spironolactone with a high dose of CPA. That's a weaker AA.
I should have added ‘in regards to androgenic suppression’, since that’s what I mean. Bicalutamide is inferior with regrowth, but superior for dealing with androgens.
Bica is inferior with regrowth?
@mryellowman what dose of Bica did you try? If 50mg how did you know it was enough to block all T & DHT ? As a monotherapy for hair loss it seems dosage should be higher.
I was using 50 mg EOD but shouldn't matter so much because of its high half-life. 50 mg doesn't block all T's.
I don't think you have to block all of them. There are lots of success with low dose of spironolactone and cypro and those are like block 50% - 60 % of the testosterone.
There was a chart which tells what dose of bica blocks estimated T's but i couldn't find it right now. Maybe ikarus will share it.
Yes it's on reddit mtfhrt channel and the rule of thumbs is pretty simple, no need for a chart. My fear with not being accurate with Bica is not blocking enough AR so DHT can still be generated. The mystery to me with Spyro is people are quick to criticize it as weak AA terrible sides but when it comes to hair regrowth it's a winner. Or is it just caused by E added to the regiment and not enough data on Bica used for that purpose?
To be fair I never saw hair regrow results with a monotherapy drug like Cypro spironolactone or Bica. If there is I'd like to read it though. Is there a raise in E level with CPA & Spyro that Bica can't provide since it doesn't block T from circulating?
That's why you should use bica with something like dutasteride. I don't think you can compensate the increased dht from bica with bica alone. There are stories here with only spironolactone and minoxidil combined, no E were added. You can dig it on this site.
https://www.gourmetstylewellness.com/interact/threads/i-prevail-the-end-of-a-long-agonizing-road.119786/
And there is this guy. Cypro , combined with high dose of minoxidil without E . This guy doesn't block all T's for sure. There should be still good amount of T circulating in his body with this regimen but seems like it doesn't matter. I don't remember exactly but i think i saw couple of success stories with spironolactone only, not even minoxidil used but its been so long since i lurk through this stories.
I don't think E level raises with CPA, logically it should be lowered because Less T = Less E for males.But since there is low levels of testosterone and dht , it can not compensate with estorgens so the body becomes estrogen dominant. That's why there is a chance to get gyno with something like cypro.