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Almas

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I was on 100mg and patches last year for a couple of months which didn't do much. Only after I added finasteride did things start to work.
Have you tried 100mg + finasteride or 50mg + finasteride? Without E
100mg should work even without finasteride, they block all androgens
 

franzliszt

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Have you tried 100mg + finasteride or 50mg + finasteride? Without E
100mg should work even without finasteride, they block all androgens
In theory it should work, but it just wasn't enough. within 3 weeks of starting finasteride my scalp itch went away, and I started feminizing.
 

tato123

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Have you tried 100mg + finasteride or 50mg + finasteride? Without E
100mg should work even without finasteride, they block all androgens
Correct me if I'm wrong, but I think DHT has more affinity for the receptor than bicalutamide, so I think a 5ar blocker is strictly necessary.
 

Pls_NW-1

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In theory it should work, but it just wasn't enough. within 3 weeks of starting finasteride my scalp itch went away, and I started feminizing.
What do you consider as feminization? What did you experience? Crazy, indeed. 150mg schould stop androgenic action (undetectable PSA) dead in tracks lol
 

Pls_NW-1

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Correct me if I'm wrong, but I think DHT has more affinity for the receptor than bicalutamide, so I think a 5ar blocker is strictly necessary.
It is! But at 150mg, Bica is OP to all androgens for the receptor because there are eg.: 1000 bicas vs. 1 DHT lol. Concentration is a key factor, it is proven that androgen concentration is much higher in balding scalp than in non-balding scalp, I really wonder why!?
 

Almas

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In theory it should work, but it just wasn't enough. within 3 weeks of starting finasteride my scalp itch went away, and I started feminizing.
Have you tried 50 or 75mg with Finasteride? Smaller doses of Bica help, or 100mg is the minimum?
Correct me if I'm wrong, but I think DHT has more affinity for the receptor than bicalutamide, so I think a 5ar blocker is strictly necessary.
Even lowering PSA by 97% doesn't stop this sh*t ...
 

tato123

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It is! But at 150mg, Bica is OP to all androgens for the receptor because there are eg.: 1000 bicas vs. 1 DHT lol. Concentration is a key factor, it is proven that androgen concentration is much higher in balding scalp than in non-balding scalp, I really wonder why!?
Nice explanation, it makes sense, but I would not risk bicalutamida without 5ar blocker in any dosage.
 

franzliszt

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What do you consider as feminization? What did you experience? Crazy, indeed. 150mg schould stop androgenic action (undetectable PSA) dead in tracks
Face softening, lowered sex drive etc. I think there's some unknown action to finasteride, given the brain fog/depression it gives me.
 

tato123

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Face softening, lowered sex drive etc. I think there's some unknown action to finasteride, given the brain fog/depression it gives me.
As far as I know bicalutamide does not cross the blood brain barrier very well, it would explain its low neural effect, most of the analogs of bicalutamide (NSAA ENZALUTAMIDA, FLUTAMIDA) cause seizures and depressive effects, unlike bicalutamide, it is said that her block is only in the AR receptors peripheries

Finasteride blocks essential male neurosteroids, in some cases it can be severe, in others the body compensates for this depression in another way.

In my opinion everyone should try finasteride before dutasteride, I took dutasteride for a few months, I couldn't stand the depression it gave me, and it ended my libido too, this is funny the effect of drugs on each one.

Finasteride decreases my libido but at an acceptable level, bicalutamide I am almost 1 week ago it may be placebo but it seems that my libido is better.

Can you tell me if you are still in this treatment and how are your results?
 

franzliszt

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As far as I know bicalutamide does not cross the blood brain barrier very well, it would explain its low neural effect, most of the analogs of bicalutamide (NSAA ENZALUTAMIDA, FLUTAMIDA) cause seizures and depressive effects, unlike bicalutamide, it is said that her block is only in the AR receptors peripheries

Finasteride blocks essential male neurosteroids, in some cases it can be severe, in others the body compensates for this depression in another way.

In my opinion everyone should try finasteride before dutasteride, I took dutasteride for a few months, I couldn't stand the depression it gave me, and it ended my libido too, this is funny the effect of drugs on each one.

Finasteride decreases my libido but at an acceptable level, bicalutamide I am almost 1 week ago it may be placebo but it seems that my libido is better.

Can you tell me if you are still in this treatment and how are your results?
The results were good at first, I moved onto injections shotly after and things were going good. I was an idiot and decided to lower my finasteride, bica and e doses at the same time and lost most of the hair I gained. My libido shot back up, with greasy hair and oily skin. Since going back on injections, finasteride and bica I haven't been able to get back to where I was, my hair still gets greasy and scalp still itches.
 

Pls_NW-1

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unlike bicalutamide, it is said that her block is only in the AR receptors peripheries
It's because its' low binding affinity. The concentrations of androgens in the brain and in the testicles are soo much higher than that of Bicalutamide.

And because of that; Bicalutamide has almost no existant effects in those areas.
 
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