Exploring The Hormonal Route. Hair=life.

JaneyElizabeth

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I have been taking topical minoxidil orally for the past five days. Not sure how much I have been taking. I've been doing 3-5 drops, but they aren't always the same size.

Still planning, since I plan on using an AA only for the first three months, I feel as though I can choose one without worrying about the effects of long term use. Since I am dove-tailing hair treatment with actual transition, I will be doing this through Planned Parenthood, which offers HRT services under Informed Consent. From what I hear, doctors are more likely to prescribe spironolactone because it is the AA they are most familiar with, Bica seems to be a little harder to convince an endo to prescribe.

I'll likely go with an AA + 4mg E2 for the first two-three months then after that time period, up E2 to 6+ mg as monotherapy. Progesterone sounds like it could be a useful medication to add at some point down the road. Right now, Finasteride is more accessible than Dutasteride, so I'll likely stick with that, at least for a while.

T and even DHT have blessed me with so many gifts over the years, but then they tried to take my hair and my near perfect skin. Now I must say good bye to them. I know I could likely preserve my hair using oral minoxidil and finasteride/dutasteride, but my ambitions are a bit grander than that...
All true especially about spironolactone in my experience and if I can do anything to help you, please let me know.
 

Pls_NW-1

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@Itsnoahkennedy another question lol sorry

Would you say that your chest ist currently normal looking? And would you like to give out a short story on your gyno journey lol. Like when it began, how it wss and when you removed it (I assume after HRT?)?

Oh and I don't understand how a surgeon can remove the whole gland without leaving a sunken chest/deformity, so it cannot return, despite of being on HRT (/lite lol).
 

Pls_NW-1

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So long story short story;

My sister suffers from hyperandgernism [diagnosed]. She may have the same problem as me; too many adrenal androgen precursors (-> DHEA-S).

The only thing helping here is Bicalutamide.
Or well, Abiraterone Acetate and maybe even Spironolactone.

And she has severe diffuse thinning, like I do.
 

Almas

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So long story short story;

My sister suffers from hyperandgernism [diagnosed]. She may have the same problem as me; too many adrenal androgen precursors (-> DHEA-S).

The only thing helping here is Bicalutamide.
Or well, Abiraterone Acetate and maybe even Spironolactone.

And she has severe diffuse thinning, like I do.
My mom seems to have baldness. She does not go bald much, she does not cure it in any way and does not complain of deterioration, but her hair is of poor quality. She may have female AHA, which is not progressing due to the low amount of T
At the same time, everything is fine with her own sister, just like with her sister's son. And my grandfather (her father) began to go bald at the age of 70. I am a loser...
Perhaps my mom is a carrier of Androgenetic Alopecia. Because my father has no bald people in his family. They say that Asians do not go bald, but I am Asian and have been balding since I was 16. I hate my destiny
 

Pls_NW-1

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My mom seems to have baldness. She does not go bald much, she does not cure it in any way and does not complain of deterioration, but her hair is of poor quality. She may have female AHA, which is not progressing due to the low amount of T
At the same time, everything is fine with her own sister, just like with her sister's son. And my grandfather (her father) began to go bald at the age of 70. I am a loser...
Perhaps my mom is a carrier of Androgenetic Alopecia. Because my father has no bald people in his family. They say that Asians do not go bald, but I am Asian and have been balding since I was 16. I hate my destiny
This is really fucked up, don't know what to do. I think I am a DHT mutant because of the backdoor pathway lol. Only Bicalutamide in high doses may help here welp.
 

Pls_NW-1

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Let's hope we can resist on Bicalutamide for the next 20 years, till a baldness cure comes out with androgen resistant follicles. fingers crossed
 

Almas

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Ayy glad to finally be able to make my account here.
Been on 6mg sublingual E & 50mg bica daily for 2 months (and finasteride for 6 months before and still taking it) and after 2 month of increased shedding I think I'm starting to see a little progress on my hairline this week. Hopefully it fixes my diffuse thinning a bit soon cause still very much struggling there. Yall are an inspiration
How are you doing?
 

Almas

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Ein has long hair. He noticed thickening after 8 months. I think Bicalutamide gave him results within the first 4 months, but he didn't notice it until his hair was branching. I don't know, perhaps the decision to increase the dosage should be applied as early as June, that is, at the 5th month
I'm running out of patience. I want to jump on the HRT, then I want to kill myself out of painful anticipation and fear. But I promised to test this dosage for the sake of others. If I take 100mg right away, we will never know which dosage is the minimum for hair.
If Bicalutamide works, you probably need 75mg. 50mg hasn't completely stopped sebum production, and I also have acne. I wonder what kind of T Ein had?
I urgently need a time machine 6 months ahead!
 

Pls_NW-1

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Gals and boyos. Hairline wants to die, we gotta rescue it!

Alright, now serious talk lol.

I am thinking about, if spironolactone would be much better than bicalutamide, for regrowth, but bica seems much safer.
 

Almas

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Maybe I should increase my dosage to 75mg right now? I start to lose hope at 50mg. But at 75mg I will definitely have gynecomastia. It is tempting to go on with 50mg and get the result without gynecomastia. That would be a cool win
 

BetaBoy

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Okay. I'll give 50mg a chance. I will try 75mg in July if I don't see results before then.
I think if you can avoid gyno it is always preferential and with NSAA's the risk only increases with the dose. If you are able to avoid gyno or any other deleterious side effect at a sustained 50mg dose but don't see the hair payoffs you were hoping for maybe consider adding something like RU to further reduce scalp AR expression before increasing your bica dose.
 

Almas

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I think if you can avoid gyno it is always preferential and with NSAA's the risk only increases with the dose. If you are able to avoid gyno or any other deleterious side effect at a sustained 50mg dose but don't see the hair payoffs you were hoping for maybe consider adding something like RU to further reduce scalp AR expression before increasing your bica dose.
RU is a dummy. Never seen him do anything. When it comes to aggressive baldness, we must increase the strength of the treatment at least one and a half times each time, otherwise we risk losing too much time. Time is very valuable if you want to keep Norwood 0
 

BetaBoy

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RU is a dummy. Never seen him do anything. When it comes to aggressive baldness, we must increase the strength of the treatment at least one and a half times each time, otherwise we risk losing too much time. Time is very valuable if you want to keep Norwood 0
Well I don't know if it is, AR saturation is the aim of the game here, I mean bicalutamide is only good because of it's long half life, it's binding affinity is actually dog sh*t.
 
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