Exploring The Hormonal Route. Hair=life.

Pls_NW-1

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You're only 17. A lot of those follicles can still be rejuvenated. Versus someone who has had slick bald areas for 20 years.
Yes, I got still vellus hair above my eyebrows lol. The NW0 hairline I had when I was 11/12. But yes, the temple recession I have now has still vellus hairs as well... I am not sure what to do. I want to avoid minoxidil because I want a long term solution for 20+ years.

My plan is continuing with Finasteride, upping soon to Dutasteride, adding 100mg Bicalutamide and 1000mg Resveratrol... but then!? I am really not sure what I should do next because that's the limit before real HRT lol.
 

JaneyElizabeth

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You're only 17. A lot of those follicles can still be rejuvenated. Versus someone who has had slick bald areas for 20 years.
Yes but I am 56, lol and I tell the young guys the same thing about relative period of dormancy mattering but then again, maybe that isn't such an important factor at all. It might just be that dormancy is hard to recover from and that younger guys simply haven't as many dormant follicles but I used to hear that breast growth and scalp hair growth are likely to be lackluster for older MtF's and I don't deny this but it hasn't been my experience at all.
 

Gergely

Experienced Member
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i'm not an expert on the matter but do to slower metabolism that comes with age fat can deposit much faster
 

JaneyElizabeth

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arthemofan sent 17 hours ago

tote ok to refer anyone to the site or me!
just have your friends post questions here, and I'll do my best to answer, but imho it's a very generic problem, not super complicated, and with a generic answer: the only thing that can really help a balding cis guy with minimal side effects is topical estrogel maybe at very high concentration (but they have to brew it themselves) directly applyied on the balding parts - as little gel as possible, just enough to make the skin quite shiny (ie pea size on the finger NOT A FULL PUMP), but OTOH as often as possible, like at least 3 times a day, and more likely 6, then washed after I can't remember how long, but the trigger time between the change of pathways, something like 20 min IIRC.
Or was it 5? It's been a while, but think of the skin like a big shield with tiny holes (where the hair emerge): rub some gel, it goes into the holes immediately. some sit on the shield and eventually go through - but not of you wash it away first. and enough will have gone in the hole that it doesn't matter if you remove some of it that's there.
This will saturate the shunt pathway of the skin (ie go through the follicles) while fully avoiding the stratum corneum, which is double bonus: the hair follicles is where they WANT the E2 to be, the rest is what would raise the blood level and deliver the side effects we want (boobz!) and they dont!!
That's the best summary I can do in 5 min, they should rly learn ab the basics of skin absorption, I made several beginners guides on r/estrogel, can't find them ATM but it's all there, summarized from books and research papers, with plenty links to learn more if some parts are unclear
actually, just feel free to copy paste the above on their forum, so they get the basics right wrt the dose, site and frequency. I don't want ppl to mess up and experience dysphoria or have to pay for gyno removal.
 

Pls_NW-1

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I think I am almost done with development as I was/am an early bloomer. So I might try HRT at 20, if Bicalutamide, Dutasteride and Minoxidil fail me.

Thanks Noah, you are such a great member!

f*** HRT haters lol
 

Pls_NW-1

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Also Dont try taking CPA mono therapy, it gets rid of both testosterone and estrogen and will do nothing for your hair by itself, and you won’t feel very good either lol.
This!
And you cant use dutasteride while on cpa, right? How long does it take to get flushed out of the body!?
 

Pls_NW-1

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You can take CPA with Dutasteride they work well together, you got it backwards it’s Bicalutamide that you can’t take Dutasteride with, though you can take finasteride with it.

Research reports shows no interaction between Bica and finasteride

Research reports show that when Bica and dutasteride are taken together there’s a huge increase of Dutasteride in the blood, because it’s not being metabolized well by the liver.
And because of that it can have many health risks such as blood clots, clinical liver injury and the list goes on!?

How is it that you can take CPA with Dutasteride, while Dutasteride inhibits the metabolization of progestins, and CPA is indeed a progestin derivate!?
 

JaneyElizabeth

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You can take CPA with Dutasteride they work well together, you got it backwards it’s Bicalutamide that you can’t take Dutasteride with, though you can take finasteride with it.

Research reports shows no interaction between Bica and finasteride

Research reports show that when Bica and dutasteride are taken together there’s a huge increase of Dutasteride in the blood, because it’s not being metabolized well by the liver.
E2-only is the way along with P4 and/or provera. Only positive sides from MPA and P4.
 

Nimos0651

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I’ve been on my regimen of 50mg spironolactone 1mg estradiol and .75mg estrogel for 2 months. I think it has reduced my erection quality slightly (not a huge change but still noticeable) is there anything I can do to stop this? Possibly not take my regimen the day I know I’m going to have sex or the day before?
 

Norwoody

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I’ve been on my regimen of 50mg spironolactone 1mg estradiol and .75mg estrogel for 2 months. I think it has reduced my erection quality slightly (not a huge change but still noticeable) is there anything I can do to stop this? Possibly not take my regimen the day I know I’m going to have sex or the day before?
Well it's probably close to steady state, meaning it would take at least a few days to see an effect. Any gyno or other sides?
 

JaneyElizabeth

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I’ve been on my regimen of 50mg spironolactone 1mg estradiol and .75mg estrogel for 2 months. I think it has reduced my erection quality slightly (not a huge change but still noticeable) is there anything I can do to stop this? Possibly not take my regimen the day I know I’m going to have sex or the day before?
cialis.
 

Almas

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871
I see that the hair quality with E improves well, provided your hair is terminal. If Bicalutamide stops baldness, in theory I can restore my hair to ideal and keep it on Bicalutamide

I have high hopes for Bicalutamide.
 

Almas

Banned
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871
Some interesting information
Castration reduces PSA by 93%. It also stops baldness and slightly thickens the existing hair, partially reverses miniaturization, which we can see in the example @Sonolmn98: "Castration stopped further balding completely but no significant regrowth was seen beside the increase n density and texture"
Bicalutamide 75mg combined with 1mg Finasteride also lowers PSA to about 90% +, but it also increases your E, so it may even be more effective than castration in terms of improving texture and reversing miniaturization. We can take the results of Sonolmn and understand what we can expect from Bicalutamide: stop baldness and some thickening of the hair with an improvement in its texture.
It took him 3 months to see the results. Bicalutamide reaches its concentration in 1 month, which means that 4 months is enough for the assessment. And this completely coincides with the experience of Maave, who claimed to have noticed the first results 4 months after starting taking Bicalutamide.

@tato123
@Pls_NW-1,
Bicalutamide will only improve the texture of your hair, and there is hardly any difference in effectiveness between 75 and 100mg, because in both cases a complete blocking of the receptors is achieved. The only way to achieve regrowth is not to increase the dosage of Bicalutamide, but to add E, because only it grows hair
Your plan is this: 75mg Bicalutamide + 1mg Finasteride. Surgery to remove gynecomastia. Adding Estradiol. After receiving the results, remove E and maintain the results on Bicalutamide.
 

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Pls_NW-1

Senior Member
My Regimen
Reaction score
1,104
Some interesting information
Castration reduces PSA by 93%. It also stops baldness and slightly thickens the existing hair, partially reverses miniaturization, which we can see in the example @Sonolmn98: "Castration stopped further balding completely but no significant regrowth was seen beside the increase n density and texture"
Bicalutamide 75mg combined with 1mg Finasteride also lowers PSA to about 90% +, but it also increases your E, so it may even be more effective than castration in terms of improving texture and reversing miniaturization. We can take the results of Sonolmn and understand what we can expect from Bicalutamide: stop baldness and some thickening of the hair with an improvement in its texture.
It took him 3 months to see the results. Bicalutamide reaches its concentration in 1 month, which means that 4 months is enough for the assessment. And this completely coincides with the experience of Maave, who claimed to have noticed the first results 4 months after starting taking Bicalutamide.

@tato123
@Pls_NW-1,
Bicalutamide will only improve the texture of your hair, and there is hardly any difference in effectiveness between 75 and 100mg, because in both cases a complete blocking of the receptors is achieved. The only way to achieve regrowth is not to increase the dosage of Bicalutamide, but to add E, because only it grows hair
Your plan is this: 75mg Bicalutamide + 1mg Finasteride. Surgery to remove gynecomastia. Adding Estradiol. After receiving the results, remove E and maintain the results on Bicalutamide.
Great post! Is this you, Almas? What was the persons treatment, and he has less acne on the forehead...
 
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