Exploring The Hormonal Route. Hair=life.

[BeardCombover]

Russian people got the worst hair genes. No wonder there are so many of them on this forum lmao. Just drink your vodka and COPE.

Agreed, with only one nuance. More frequent baldness in Russia is mostly not gene determined, more like environmental dependent. Terrible climate, lack of freedom, overall wartime stress play a much higher role imo. In my case, just getting the FK outa there (before war started) helped with my hair situation and overall mental stability tremendously!

 

[Almas_NW0]

I am from Russia. In a group of 300 people aged 18-25, not a single one has baldness. I have seen young people with baldness a couple of times in my life. But in 30+ years it is more common

 

[exwhyyou]

estrogen isnt enough you need a high protein diet and head massages to get the estrogen up to your scalp

 

[exwhyyou]

@Adri23 ^^^^^^^^^^^

 

[exwhyyou]

also you can’t orgasm. orgasming ruins that swaggy bounciness for like a week

 

[exwhyyou]

100s of pages of this bullshit and no one is talking about the importance of swaggy bounciness!!!! i f*****g hate you guys

 

[Adri23]

Literally nothing works for hair loss if you have aggressive baldness and you caught it somewhat 'late'. I am just doing all this cause I hate f*****g testosterone & DHT and it destroyed my entire body and hair, nothing else

 

[exwhyyou]

Literally nothing works for hair loss if you have aggressive baldness and you caught it somewhat 'late'. I am just doing all this cause I hate f*****g testosterone & DHT and it destroyed my entire body and hair, nothing else

i hate that you cant say anything here. you already recovered from hair loss with castration now your hair looks sh*t because your malnourished and gravity drained all the blood from your scalp

 

[Dav1234]

Is there a difference between taking 50mg Bica daily vs every other day?

 

[BeardCombover]

Is there a difference between taking 50mg Bica daily vs every other day?

50mg EOD = 25mg daily, you will basically have the same steady state levels. Taking 25mg is marginally safer tho, cause even with same steady state, the initial spike of taking 50mg is higher and might influence your liver more.

 

[Dav1234]

For people that stopped hairloss do you still shed a decent amount?

 

[exwhyyou]

For people that stopped hairloss do you still shed a decent amount?

yes and honestly the shedding was accumulating before i got more militant about calories and head massages

 

[Dav1234]

I’m thinking about taking 50mg bica twice weekly with my estrogen injection. It seems to work best when I use in conjunction but Bica feels useless when using on other days seems it may do worsez

 

[BeardCombover]

I’m thinking about taking 50mg bica twice weekly with my estrogen injection. It seems to work best when I use in conjunction but Bica feels useless when using on other days seems it may do worsez

Bica is trash, and should only be used if monotherapy isn't enough for some reason (same as spironolactone and cpa) and only in a small dose (12.5-15mg/day). If you want to do it correctly, taper off it and take your blood tests after month w/o it, cause it makes blood tests useless when included and there's a high chance you don't need it at all.
Levels needed for mono are:
LH<0.5 iu/l. It shows if your HPG axis it still intact or, simplier, if your testies are still making test.
SHBG≈80-115 nmol/l. Basically works like AA and binds to free T, preventing half of it from interacting with receptor. You dont need more than 115 tho, cause it binds to free E also (less effectively, but still), especially if your T is already low, which it should be (T≈10-45ng/dl is needed).
E2≈250-350 pg/ml. You dont need more in most cases, cause its enough to obliterate your LH and more E=more SHBG, which is counterproductive.
If, even with these levels, you feel smth is off, you should also check your DHEA-S (and 17-OH progesterone if needed) to see if your adrenal gland is mb enlarged and makes too much androgens and 3α-Androstanediol (another androgen). Thyroid panel might help too.
If any of these androgens will be elevated and your main panels (CMP, CBC, lipids) are healthy, you'll get the permision to use Bica. GL.

 

[Dav1234]

Bica is trash, and should only be used if monotherapy isn't enough for some reason (same as spironolactone and cpa) and only in a small dose (12.5-15mg/day). If you want to do it correctly, taper off it and take your blood tests after month w/o it, cause it makes blood tests useless when included and there's a high chance you don't need it at all.
Levels needed for mono are:
LH<0.5 iu/l. It shows if your HPG axis it still intact or, simplier, if your testies are still making test.
SHBG≈80-115 nmol/l. Basically works like AA and binds to free T, preventing half of it from interacting with receptor. You dont need more than 115 tho, cause it binds to free E also (less effectively, but still), especially if your T is already low, which it should be (T≈10-45ng/dl is needed).
E2≈250-350 pg/ml. You dont need more in most cases, cause its enough to obliterate your LH and more E=more SHBG, which is counterproductive.
If, even with these levels, you feel smth is off, you should also check your DHEA-S (and 17-OH progesterone if needed) to see if your adrenal gland is mb enlarged and makes too much androgens and 3α-Androstanediol (another androgen). Thyroid panel might help too.
If any of these androgens will be elevated and your main panels (CMP, CBC, lipids) are healthy, you'll get the permision to use Bica. GL.

And if I had reflex from finasteride would topical work better and does topical block more scalp dht any studies on this?

 

[Dav1234]

Bica is trash, and should only be used if monotherapy isn't enough for some reason (same as spironolactone and cpa) and only in a small dose (12.5-15mg/day). If you want to do it correctly, taper off it and take your blood tests after month w/o it, cause it makes blood tests useless when included and there's a high chance you don't need it at all.
Levels needed for mono are:
LH<0.5 iu/l. It shows if your HPG axis it still intact or, simplier, if your testies are still making test.
SHBG≈80-115 nmol/l. Basically works like AA and binds to free T, preventing half of it from interacting with receptor. You dont need more than 115 tho, cause it binds to free E also (less effectively, but still), especially if your T is already low, which it should be (T≈10-45ng/dl is needed).
E2≈250-350 pg/ml. You dont need more in most cases, cause its enough to obliterate your LH and more E=more SHBG, which is counterproductive.
If, even with these levels, you feel smth is off, you should also check your DHEA-S (and 17-OH progesterone if needed) to see if your adrenal gland is mb enlarged and makes too much androgens and 3α-Androstanediol (another androgen). Thyroid panel might help too.
If any of these androgens will be elevated and your main panels (CMP, CBC, lipids) are healthy, you'll get the permision to use Bica. GL.

Already use Bica. But want to lower the amount I take it because I noticed it worked best on days I take my estrogen injections.

 

[BeardCombover]

And if I had reflex from finasteride would topical work better and does topical block more scalp dht any studies on this?

Studies on topical finasteride are conflicted AFAIK. And no, it doesn't block more than oral, cause serum dht is more reliable vs all dht in your body.
Reflex hyperandrogenicity is a syndrome, which can be caused by anything and finasteride might not be the main culprit.
Anyways, finasteride kinda sucks and its less effective than duta, especially on hrt. And you don't need it if you are on bica.

Already use Bica. But want to lower the amount I take it because I noticed it worked best on days I take my estrogen injections.

Bica has a pretty long half life, i really doubt it makes any difference when its been used if you are on a steady state. Might be an effect of estrogen itself, which made you think that.

 

[Almas_NW0]

Estradiol alone is not enough to stop my skin from being oily. I use Bika because it reduces oiliness, tightens pores and improves skin condition. 37.5mg 3 times a week.

 

[Dav1234]

Estradiol alone is not enough to stop my skin from being oily. I use Bika because it reduces oiliness, tightens pores and improves skin condition. 37.5mg 3 times a week.

if I possibly had reflex from finasteride. Oily hair/ hairloss but now I’m on estrogen and Bica can I start finasteride back up since testerone is eliminated?

 

[BeardCombover]

Estradiol alone is not enough to stop my skin from being oily. I use Bika because it reduces oiliness, tightens pores and improves skin condition. 37.5mg 3 times a week.

Well, i mean, using lifelong bica can only be justified if you tried all the other (safer) options IMO. Especially if its only used for oily skin. Especially considering it can fk up your liver pretty fast at any time basically.
What i would of done first:
Get on Duta 0.5 + high dose of Zinc for like 2 months.
If no improvements, add rectal Progesterone (it can make things better or worse tho, about 50/50). Melatonin before sleep with Prog (its optional, good for sleep and helped me somehow counter cortisol and adrenalin, which are both bad for skin if elevated).
If still no improvement, stop Prog and here goes blood tests. Sex hormone tests i mentioned in the other post + DHT and thyroid panel can be done in Lab4u for example, for pretty cheap. All the others (CMP, CBC, lipids), can be done in polyclinic for free if you're from Russia (if im not mistaken). Adrenal and thyroid tests you dont need to take often, but they are good to know anyways at least once in you life.
Tests could show elevated Prolactin for example, that Cabergoline could handle pretty quickly. Boron or Tongkat for elevated SHBG. For adrenal problems, corticosteroids could help. All those are safer than bica if used properly, IMO, and thats just a few examples.