Exploring The Hormonal Route. Hair=life.

[sg2000]

No clue, thats very individual. The only thing ill mention (that i didnt before) is that on high E2 dose you just need to know you SHBG. It can be a marker of elevated E metabolites, E1 for example (which is a pretty strong coagulant and can cause blood clots). You could also just test E1 and compare to E2. If it's 5+:1 ratio, you should consider loweing E2 dose.

can too high shbg levels or e2 levels can block hair growth? If yes how much?

 

[sg2000]

That is my main concern since my levels of e2 were 429 pg ml 2 weeks after the prevoius injections so ive wondered how high levels were just after the injection @BeardCombover

 

[losingbattle88]

I dont rly care mate, I might be a coward but I achieve what I wanted, and I can ensure you not many people has the balls to inject alcohol in a part of their bodies. It takes too much courage that not everyone has

I

what abt when u get off ur shift ur just gonna go home and drink and jerk again?

No I will never drink again.

 

[sg2000]

Dunno, but it might be the only chance for some lost causes like this:
View attachment 189872

if my dht lowered to 22 ng dl after 1 year of dutasteride and then after starting hrt down to 5,0 ng dl am i excluded ?

 

[Adri23]

There is an interesting post on reddit about it:

https://www.reddit.com/r/estrogel/comments/jcxpw2

I still don't trust that theory. They are saying the culprit is DHEA and DHEA-S yet when my DHEA and DHEA-S were higher back in 2023 my DHT was 4.5-5 ng/dl and now my DHEA and DHEA-S are lower and my DHT sits on 18 to 22 ng/dl. I won't say the theory is fake by any means, some peope could fit on that theory but it is not true for me.

 

[Adri23]

I am gonna start prog again and this time Im gonna keep taking it cause i have nothing to lose.

In this study '' https://pubmed.ncbi.nlm.nih.gov/25201454/ '' they mention this:

The combination of abiraterone and dutasteride decreased testosterone and DHT in the presence of progesterone but increased DHT in the absence of progesterone.

I will not be using abiraterone for obvious reasons but maybe e2 + bica + dutasteride kinda leads to a similar blockade of androgens in non high DHEA/DHEA-S people, so maybe prog could decrease dht in presence of dutasteride + e2 + bica in people without heightened DHEA and DHEA-S (again I am speculating and I will test it since I have nothing to lose at this point).

I am starting with 100 mg prog rectally and will increase it if I don't feel anything is improving or if my next blood test shows similar DHT as now. If my DHT gets lower I will keep the 100 mg and if it gets higher I will stop it entirely.

 

[SnortingFinasteride]

I still don't trust that theory. They are saying the culprit is DHEA and DHEA-S yet when my DHEA and DHEA-S were higher back in 2023 my DHT was 4.5-5 ng/dl and now my DHEA and DHEA-S are lower and my DHT sits on 18 to 22 ng/dl. I won't say the theory is fake by any means, some peope could fit on that theory but it is not true for me.

your free T level is higher as well, probably corresponding to the increase in DHT seen

And your SHBG is very high. It is soaking up all the E that you have in your body, leaving you with more fractional free T

 

[Adri23]

your free T level is higher as well, probably corresponding to the increase in DHT seen

And your SHBG is very high. It is soaking up all the E that you have in your body, leaving you with more fractional free T

It is not higher than when i had very low DHT tho(in july 2023 i had 3 pg/ml T yet the lowest DHT i ever had), so it still makes no sense. SHBG is not that high, only in august 2024. SHBG actually helps because it binds way more to T and DHT than e2 so it is doing its function there acting as an AA

 

[SnortingFinasteride]

It is not higher than when i had very low DHT tho(in july 2023 i had 3 pg/ml T yet the lowest DHT i ever had), so it still makes no sense. SHBG is not that high, only in august 2024. SHBG actually helps because it binds way more to T and DHT than e2 so it is doing its function there acting as an AA

Yet it makes no sense how DHT shot to the double digits. And also, SHBG does prefer binding to T and DHT more, but when androgen levels are already castrate range / low levels, it starts soaking up Estradiol instead. Since you have high E levels, high SHBG is doing more harm in this case

 

[Adri23]

Yet it makes no sense how DHT shot to the double digits.

Yeah I think i am an exception cause i dont have high DHEA-S/DHEA/Androstenedione, I also take dutasteride so it makes things even weirder. As I said I don't have many new stuff to use anymore so I will try with progesterone and see what I can achieve

And also, SHBG does prefer binding to T and DHT more, but when androgen levels are already castrate range / low levels, it starts soaking up Estradiol instead. Since you have high E levels, high SHBG is doing more harm in this case

Yeah im planning on lowering it when I get my dht under control and get physically castratred which should happen at any point cause as i said previously my testicles are ischemic and it is a matter of time since they become necrotic and start to give me serious issues. I remember when I had lower shbg I had more feminization but I always blame on dht and not shbg but prob both are contributing.

 

[sg2000]

Yet it makes no sense how DHT shot to the double digits. And also, SHBG does prefer binding to T and DHT more, but when androgen levels are already castrate range / low levels, it starts soaking up Estradiol instead. Since you have high E levels, high SHBG is doing more harm in this case

When high e2 levels can spike shbg and so doing problems? Over 1000 pg ml?

 

[SnortingFinasteride]

When high e2 levels can spike shbg and so doing problems? Over 1000 pg ml?

Yes

 

[SnortingFinasteride]

Yeah I think i am an exception cause i dont have high DHEA-S/DHEA/Androstenedione, I also take dutasteride so it makes things even weirder. As I said I don't have many new stuff to use anymore so I will try with progesterone and see what I can achieve

Yeah im planning on lowering it when I get my dht under control and get physically castratred which should happen at any point cause as i said previously my testicles are ischemic and it is a matter of time since they become necrotic and start to give me serious issues. I remember when I had lower shbg I had more feminization but I always blame on dht and not shbg but prob both are contributing.

If you found the cause make sure to tell us. This sh*t is so criminally understudied it's crazy

 

[Adri23]

If you found the cause make sure to tell us. This sh*t is so criminally understudied it's crazy

I will. I rly hope progesterone can save me cause if it doesnt, it's over for me

 

[sg2000]

Yes

if my e2 levels were 429 pgml after 14 days my prevoius injections is there a chance that they might have been higher on the 7th day or l 2-3 days after the first one? The simulator is not trustworthy to be honest or maybe im just a dickhead and cant use it

 

[SnortingFinasteride]

I will. I rly hope progesterone can save me cause if it doesnt, it's over for me

What's the reason you're adding prog ?

 

[Adri23]

What's the reason you're adding prog ?

Try to see if it fixes my metabolism. It is so fucked rn maybe it helps with dht or maybe not who knows

 

[SnortingFinasteride]

Try to see if it fixes my metabolism. It is so fucked rn maybe it helps with dht or maybe not who knows

Prog can convert to DHT. Be careful

 

[SnortingFinasteride]

if my e2 levels were 429 pgml after 14 days my prevoius injections is there a chance that they might have been higher on the 7th day or l 2-3 days after the first one? The simulator is not trustworthy to be honest or maybe im just a dickhead and cant use it

Yes. If 429 pg/ml is your trough level (the lowest level before your next injection), then you need to lower your E dosage. Your levels are supraphysiologic

Test for SHBG to be absolutely sure. If it's more than 100, then reduce your E

 

[Adri23]

Prog can convert to DHT. Be careful

Yes Im aware of it but it also help some people, it is a 50/50 chance. My next blood test is in late may so in the worst case scenario i would be like 2 months with high DHT which at this point it doesnt matter since i have been having high DHT for more than a year now. Also I am using dutasteride, the chances are lower