Exploring The Hormonal Route. Hair=life.

[pentobean]

My E and T levels are insane
T is 67ng/dl
E is 317ng/dl
My dht went from 111ng/dl when I tested pre finasteride and now it’s at 16ng/dl

 

[Seanrutty]

I wouldnt be that hyped tho. Every single drug for hair loss has failed till now. We are still using meds developed between 1992-2001 to treat Androgenetic Alopecia so yes dont expect anything from this industry anymore honestly. Also kintor already failed once, so I have even less hopes.

I get that but IF this works then it would be huge.. bica and all that female sh*t would be done!! Just put some gt20029 on once a week and be good

 

[Adri23]

I get that but IF this works then it would be huge.. bica and all that female sh*t would be done!! Just put some gt20029 on once a week and be good

Well for me estradiol has more benefit than only hair. It gives smooth skin that T cant give. Gives different fat distribution on face which makes people look younger in general and ofc you get rid off that annoying libido 24/7 that T causes. I will have no testicles soon so there is no way I will inject testosterone when estradiol have more benefits(at least from my point of view). Also I havent gotten feminization so I'm good still living as a man without any issue. But yeah some ppl would like it more than HRT if it rly works as in paper, but anyways it will prevent miniaturization, wont cause any big regrowth,.maybe if you catch it early but def not if you have been balding for 10+ years

 

[Seanrutty]

Well for me estradiol has more benefit than only hair. It gives smooth skin that T cant give. Gives different fat distribution on face which makes people look younger in general and ofc you get rid off that annoying libido 24/7 that T causes. I will have no testicles soon so there is no way I will inject testosterone when estradiol have more benefits(at least from my point of view). Also I havent gotten feminization so I'm good still living as a man without any issue. But yeah some ppl would like it more than HRT if it rly works as in paper, but anyways it will prevent miniaturization, wont cause any big regrowth,.maybe if you catch it early but def not if you have been balding for 10+ years

I kinda agree but I’ve seen ppl regrow dead zones but it’s super rare but even in my case I could get one little hair transplant then just use gt and be over this hair sh*t.. but again like you said we’ll see how it goes.. as far as bica if you had to choose just one in my case would you pick bica or cpa?? If you had to choose and not both but just one

 

[Adri23]

I kinda agree but I’ve seen ppl regrow dead zones but it’s super rare but even in my case I could get one little hair transplant then just use gt and be over this hair sh*t.. but again like you said we’ll see how it goes.. as far as bica if you had to choose just one in my case would you pick bica or cpa?? If you had to choose and not both but just one

Thing is if you are gonna use estradiol bica is best. But if not bica can be an issue if you have aromatization issues, cause T normally aromatize into T, but if you have a sh*t aromatase enzyme like me, all the T will just be transformed into DHT so you will need dutasteride 100%, but you will end with no main hormone. If your body is good at aromatizing T you will end up with highish e2(not sure how much since I've never tried bica mono + im bad aromatizer) which will be worse than using estradiol + bica cause if you want to make bica works on a T dominant body you will indeed need large bica dosages and you will risk liver issues.

On the other hand cpa is better lowering T alone but has lot of side effect + prolactin elevations that could destroy your hair and even increase DHEA-S.

Imo if you are going for the oral anti androgen route it's best to use estradiol + dutasteride cause antiandrogens alone or combined with dutas is not good long term cause your body need a main hormone to be healthy + you will run liver issues eventually.

For short term you have expensive sh*t like GnRH agonists which will shut down T production but again you wont have any sex hormone and you will have troubles

 

[losingbattle88]

I get that but IF this works then it would be huge.. bica and all that female sh*t would be done!! Just put some gt20029 on once a week and be good

Systemic sides bro.

 

[GRme11]

Oh and again with the fagron test it will show if there’s a back door pathway going on?? Just wanted to make sure they want $500 so making sure that’s in there too unless that’s just a possible on a test

I just provided the brochure the other day. It’s all there: https://login.fagrongenomics.com/files/demo/EN-TrichoTest_Brochure.pdf

Yes, the test measures the activity of the 5AR1 and 5AR2, plus many more. Please, read it…

Although, 500$ it’s steep, but IF money it’s not the problem, I would say go for it.

 

[1241241412]

Systemic sides bro.

hey

 

[BeardCombover]

Thing is if you are gonna use estradiol bica is best. But if not bica can be an issue if you have aromatization issues, cause T normally aromatize into T, but if you have a sh*t aromatase enzyme like me, all the T will just be transformed into DHT so you will need dutasteride 100%, but you will end with no main hormone. If your body is good at aromatizing T you will end up with highish e2(not sure how much since I've never tried bica mono + im bad aromatizer) which will be worse than using estradiol + bica cause if you want to make bica works on a T dominant body you will indeed need large bica dosages and you will risk liver issues.

On the other hand cpa is better lowering T alone but has lot of side effect + prolactin elevations that could destroy your hair and even increase DHEA-S.

Dunno guys, I decided to listen to you and give Bica another chance. I crushed Bica tablets and put them into capsules to mb avoid stomach irritation it caused me last time. I think it indeed helped with irritation, but today I woke up with sharp pain in my left kidney area. I never felt kidney pain until now, was really bad. Today is the 3rd day on this drug, I took 50mg total and I felt terrible all day. Never again...
I get it. mb I'm just one of a few unlucky ones totally intolerant to it, but the amount of sides it already given me makes me wonder tbh.

 

[BeardCombover]

I have done a CT scan of my entire body, an abdominal ultrasound, gastroscopy and colonoscopy. Everything was normal there just had H pylori which I eradicated. I am positive in SIBO now so def gotta get that under control. I still need to test bile acids. Lipase was at 23 U/L and Alpha Amylase was at 27 U/L according to the blood test done back when I got hospitalized in late february. I could try the supplements, I will have to take most of them anyways to treat SIBO. I have been like this for years and in the first year of HRT I had the dht at 5.7 ng/dl and 3a diol g in 0.10 ng/dl and now I got it in 0.08 ng/dl so not a big change tho my dht spiked badly and as I said everything is the same as back then(yes even the gastrointestinal issues and bloating I have that even before hrt) so I dont fully understand how things changed dramatically vs a year ago.

The only theory I had from a while ago is that my SHBG started to increase, my free T kept going lower and I am using bica, so my only logic theory was possible upregulation of 5ar1 due to near 0 Testosterone, but I tried to stop bica for a month and a half then did a blood test and DHT wasnt lower, so I resumed it. Maybe I didnt give enough time to let it leave my body entirely idk, but I did the blood test after a month and a half cause bica stays in the system for 30 fays when you stop it.

You're doing great btw. Ye, totally test bile acids, and I would do gastrin as well.

 

[Adri23]

Dunno guys, I decided to listen to you and give Bica another chance. I crushed Bica tablets and put them into capsules to mb avoid stomach irritation it caused me last time. I think it indeed helped with irritation, but today I woke up with sharp pain in my left kidney area. I never felt kidney pain until now, was really bad. Today is the 3rd day on this drug, I took 50mg total and I felt terrible all day. Never again...
I get it. mb I'm just one of a few unlucky ones totally intolerant to it, but the amount of sides it already given me makes me wonder tbh.

It's ok to not use bica if you dont have any short of adrenal T production or some of that stuff. Tbh if you dont have weird conditions all you need is estradiol and maybe just maybe dutasteride for stubborn dht if there is any or if you use prog and want to avoid some conversion in case it happens

 

[Adri23]

You're doing great btw. Ye, totally test bile acids, and I would do gastrin as well.

Aight im gonna pay for those ones. Hope they are not that expensive hehe. If they are in range I wouldn't know where to aim to lower that dht honestly, I think I have tried almost everything hormone related. My body just turned on a switch and I cant turn it off

 

[BeardCombover]

It's ok to not use bica if you dont have any short of adrenal T production or some of that stuff. Tbh if you dont have weird conditions all you need is estradiol and maybe just maybe dutasteride for stubborn dht if there is any or if you use prog and want to avoid some conversion in case it happens

I had around 11ng/dl DHT last time i measured. My hair is ok, but kinda became more coarse lately, so I decided to try Bica to see how it effects my hair. Hair indeed became much softer after 3 days, so It proved my point. At least I got that covered. =(

 

[BeardCombover]

Dunno why I did this sh*t.. I already paid for blood tests, and I feel they're gonna be all fked because of this fkin drug.

 

[Adri23]

I had around 11ng/dl DHT last time i measured. My hair is ok, but kinda became more coarse lately, so I decided to try Bica to see how it effects my hair. Hair indeed became much softer after 3 days, so It proved my point. At least I got that covered. =(

11 ng /dl is ok, you can have better chances with dutasteride than with bica because it also gives you side effects.

Dunno why I did this sh*t.. I already paid for blood tests, and I feel they're gonna be all fked because of this fkin drug.

It's been 3 fays, shouldnt be a major change

 

[BeardCombover]

Dunno why I did this sh*t.. I already paid for blood tests, and I feel they're gonna be all fked because of this fkin drug.

Phew... they sent my money back.

 

[BeardCombover]

It's been 3 fays, shouldnt be a major change

I feel kinda bad and I worry that smth is fked up tbh.

11 ng /dl is ok, you can have better chances with dutasteride than with bica because it also gives you side effects.

Dunno, I tried 2mg Duta for 2 months with only E, it didn't do sh*t for some reason, worked same as 0.5.

 

[BeardCombover]

I feel like because of a fucked up ACTH my adrenal androgens tend to elevate from time to time. It gets better when I stop trying new things. I felt great past few weeks, dunno why I did this, never again! Gonna go sleep, nn.

 

[Adri23]

I feel kinda bad and I worry that smth is fked up tbh.

Health wise maybe but hormones i don't think so

Dunno, I tried 2mg Duta for 2 months with only E, it didn't do sh*t for some reason, worked same as 0.5.

Damn 2 mg is a good dosage. Weird it didnt do anything. But you know bica will be good if you have kinda high free T, wont do that much for dht unless you use like 50 mg or more daily which I think it will make you sick if you are already sick after 3 days. Also bica dries my skin too much. I really want to stop bica but Im afraid my minoxidil hypertrichosis will get worse(it's already kinda bad to be on hrt)

I feel like because of a fucked up ACTH my adrenal androgens tend to elevate from time to time. It gets better when I stop trying new things. I felt great past few weeks, dunno why I did this, never again! Gonna go sleep, nn.

Yeah sometimes we do weird stuff, just like me when I increased bica to 25 mg daily gor no reason. All that said I hope you get better, gn!

 

[GRme11]

I feel like because of a fucked up ACTH my adrenal androgens tend to elevate from time to time. It gets better when I stop trying new things. I felt great past few weeks, dunno why I did this, never again! Gonna go sleep, nn.

IF your hair is fine on the stack you are on, then don’t do any changes. If you are happy with your hair and it looks/feels good, no changes are needed. Just stick to your stack.

I just wanted to ask, why metformin and melatonin? For their other benefits? You have problem with your blood sugar, for example? I would personally remove them if it’s for hair. There are studies for both that shows they inhibit aromatase activity. Also, taurine can enhance testosterone production and that’s same for zinc. Sorry, but I personally see if something can potential affect hair when adding it. My suggestion for someone is to only add supplements when they have deficiencies and they really need it. Every factor, every change can contribute to hair loss.

*This is just my experience. I tried adding supplements all these years without thoroughly researching how they affect aromatase, testosterone, etc., and they were affecting my hair, causing it to shed more and become thinner. Of course, every person is different and it will be different for everyone.

*I'm not trying to be an expert, I'm just telling my experience. For others, something that didn't help me may help them and vice versa.

But again, if your hair is doing great with your current regimen, no changes are needed.