finasteride v spironolactone

[fairhaired]

I know that Finasteride is something that most people highly recommend, but when I tried it the sides were just not worth it.

For the last 6 months I've been using spironolactone cream, to what I think have been decent results, but nothing amazing, as my hair is still steadily receding. I am between a Norwood 1 OR Norwood 2 I would say. I also regularly use nizoral. I know that everyone on here emphasises the importance of a solid anti-androgen blocker so My question is: what could, or should, I add to my S5 cream?

And also, I know it's not a DHT blocker, but should I start using Rogaine? How important is it?

Would really appreciate any recommendations, especially with regards to the anti-androgen addition. Thank you.

 

[slurms mackenzie]

How often are you using the cream?

Perhaps you could use it more often.

 

[fairhaired]

Thanks for the replies!

sir chugalot - I use s5 twice a day, before bed, and when i wake up.

With regards to the two recommendations from 'finfighter' ; thanks a lot for that, will have a little look at them two.

 

[slurms mackenzie]

well using spironolactone more would be a complete pain in the *** then

Some people would add revivogen to the mix, as if you're still losing slowly, you still need more punch blocking the dht.

I'm guessing it's weaker than some of the topicals mentioned in FinFighters sig, CB 03 01 truly looks awsome, but it looks like a hassle to get hold of and no-one knows when the first batch will arrive. Revivogen has the advantage that you could get it tommorow or the day after.

After dropping finasteride, i'm on spironolactone twice a day and revivogen, i can't say whether or not it will be successful, but it should tide me over until CB 03 01 becomes more commonplace (ie more labs selling it), which is what i predict will happen.

minoxidil won't stop you from losing hair, but should make you grow more hair, this hair makes it look like you're losing less hair, people can have great results with it lasting for years.

I personally would only want to add minoxidil for some regrowth once i'd got the hair loss under control via dht inhibition, otherwise the minoxidil could disguise the fact your losing hair.

 

[fairhaired]

well using spironolactone more would be a complete pain in the *** then

Some people would add revivogen to the mix, as if you're still losing slowly, you still need more punch blocking the dht.

I'm guessing it's weaker than some of the topicals mentioned in FinFighters sig, CB 03 01 truly looks awsome, but it looks like a hassle to get hold of and no-one knows when the first batch will arrive. Revivogen has the advantage that you could get it tommorow or the day after.

After dropping finasteride, i'm on spironolactone twice a day and revivogen, i can't say whether or not it will be successful, but it should tide me over until CB 03 01 becomes more commonplace (ie more labs selling it), which is what i predict will happen.

minoxidil won't stop you from losing hair, but should make you grow more hair, this hair makes it look like you're losing less hair, people can have great results with it lasting for years.

I personally would only want to add minoxidil for some regrowth once i'd got the hair loss under control via dht inhibition, otherwise the minoxidil could disguise the fact your losing hair.

Thanks again Sir Chugalot, appreciate it. Having had a look at FinFighters sig, I agree with you on CB 03 01 and RU, with regards to their availability. Revivogen certainly interests me in the meantime, especially with people having pretty decent results.

My question is: How would it best be used, alongside my spironolactone cream? spironolactone in the morning, Revivogen at night? Or both at the same time, considering S5 cream is supposed to be used twice a day.

Thanks a lot again.

 

[1750]

given testosterone is at it's peak in the morning... using spironolactone at this time makes sense...

RE revivogen.. understand they have revised the formula... not sure if you get away avoiding the yellowish tinge to the product that comes from the saw palmetto and beta sisterols in it... (would have to read about the revised product.. but the old one was stain city).

so if you do add revivogen to you regime and use it at night... don't sleep on your best linen as your pillow can get stained to sheit ...

 

[John979]

I tried spironolactone both alone and in prescription Proxiphen. Neither provided any real regrowth. At one point I was using Xanfrox 15% Plus along with Proxiphen. No real regrowth. In the past, I tried oral finesteride plus minoxidil. No real regrowth.

Then, instead of looking at things from the perspective of what might work, I began to think more critically -- why is this not working for me?

Regarding spironolactone, I came to the conclusion that its anti-angiogenic properties make it a poor AI choice for somebody with aggressive hair loss such as myself. I also began thinking that maybe minoxidil was not the best hair stimulant, at least when used alone.

That's when I decided to give topical dutasteride plus 2% ketoconazole a try. That combination is the only combination of agents to provide me meaningful regrowth.

 

[1750]

That's when I decided to give topical dutasteride plus 2% ketoconazole a try. That combination is the only combination of agents to provide me meaningful regrowth.

the soft tissue on the scalp makes it more permeable... you no systemic absorption from dutasteride at all?? is very powerful stuff! (personally tried it topically... and I got sides)..

 

[John979]

That's when I decided to give topical dutasteride plus 2% ketoconazole a try. That combination is the only combination of agents to provide me meaningful regrowth.

the soft tissue on the scalp makes it more permeable... you no systemic absorption from dutasteride at all?? is very powerful stuff! (personally tried it topically... and I got sides)..

I apply every other day about 0.33 mg per ml of vehicle.

 

[1750]

That's when I decided to give topical dutasteride plus 2% ketoconazole a try. That combination is the only combination of agents to provide me meaningful regrowth.

the soft tissue on the scalp makes it more permeable... you no systemic absorption from dutasteride at all?? is very powerful stuff! (personally tried it topically... and I got sides)..

I apply every other day about 0.33 mg per ml of vehicle.

cool.. glad it works for you wish it did for me

 

[LooseItAll]

I am testing spironolactone ATM. Keep in mind regrowth is rare, the main goal with AA should be maintaining.

 

[slurms mackenzie]

Thanks again Sir Chugalot, appreciate it. Having had a look at FinFighters sig, I agree with you on CB 03 01 and RU, with regards to their availability. Revivogen certainly interests me in the meantime, especially with people having pretty decent results.

My question is: How would it best be used, alongside my spironolactone cream? spironolactone in the morning, Revivogen at night? Or both at the same time, considering S5 cream is supposed to be used twice a day.

Thanks a lot again.

I'm no expert on this but i think people who use one of the topical twice a day put the revivogen on before the spironolactone, the new forumula really isn't that sticky, i've been putting it on 1ml before going to work and then an extra .25 ml on my crown in the evening, then the spironolactone get's put on just before bedtime.

Its worth adding though that i'm going to jump ship to cb 03 01 soon more as a convenience thing than anything else the problem isn't the revivogen it's the spironolactone.

 

[John979]

I am testing spironolactone ATM. Keep in mind regrowth is rare, the main goal with AA should be maintaining.

You would still be better off with topical dutasteride.

 

[fairhaired]

I am testing spironolactone ATM. Keep in mind regrowth is rare, the main goal with AA should be maintaining.

You would still be better off with topical dutasteride.

Where could I get Dudasteride? Is it expensive, and more to the point: is it more effective than Revivogen? Thanks again.

 

[LooseItAll]

I am testing spironolactone ATM. Keep in mind regrowth is rare, the main goal with AA should be maintaining.

You would still be better off with topical dutasteride.

Doesn't duta absorb systemically?

 

[John979]

I am testing spironolactone ATM. Keep in mind regrowth is rare, the main goal with AA should be maintaining.

You would still be better off with topical dutasteride.

Where could I get Dudasteride? Is it expensive, and more to the point: is it more effective than Revivogen? Thanks again.

I don't view Revivogen as a very effective treatment for aggressive hair loss.

 

[John979]

I am testing spironolactone ATM. Keep in mind regrowth is rare, the main goal with AA should be maintaining.

You would still be better off with topical dutasteride.

Doesn't duta absorb systemically?

To date, I have not seen any studies quantifying DHT absorbtion. The one study on topical dutasteride and regrowth did not do any hormonal profiling, although no side effects regarding decreased libido were reported.

In my own experiment, I propose that only 1/3 the recommmed oral dose is effectively absorbed. This is on the assumption that 80% of the topical dose is absorbed and I apply a bit less than 0.5 mg every other day.

 

[Bryan]

To date, I have not seen any studies quantifying DHT absorbtion. The one study on topical dutasteride and regrowth did not do any hormonal profiling, although no side effects regarding decreased libido were reported.

I've never seen or heard of a study using topical dutasteride. Can you cite it for me?

 

[John979]

To date, I have not seen any studies quantifying DHT absorbtion. The one study on topical dutasteride and regrowth did not do any hormonal profiling, although no side effects regarding decreased libido were reported.

I've never seen or heard of a study using topical dutasteride. Can you cite it for me?

http://panarabderm.org/en/components/co ... 37-145.pdf

 

[Bryan]

Thanks for providing that interesting study, although I wouldn't exactly consider injected dutasteride to be the same as topical dutasteride! :shock: