Finasteride's Effect on Scalp DHT Levels

BaldingHelpMe

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I will definitely take it every day from now on... but I do want to find some of the studies that were mentioned... mainly on IC50 variances in different tissues and some of the inconsistencies of studies.

This is something called dosage schedule. I read that 24-hour is most effective; even 12-hour is less effective than 24-hour. So definitely try to take it every day around the same time.
 

Prada1

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Actually, Bernstein usually prescribed dutasteride these days. I don't think he prescribes
Finasteride any more.

The common dosage of Finasteride, which many men did well with, was 1.25 milligrams.

In other words, Proscar (five milligram Finasteride), cut in fourths.

That usually did between 70 - 75 % DHT reduction. Dustasteride is much better, and 0.5 milligrams
reduces DHT by ninety percent.

For the record, I myself (and I have Norwood 3v hair, used to have Norwood five back in 2013, use
liquid Finasteride.

Liquid Finasteride is basically the same, except is reduces DHT by slightly more (~ 80% DHT reduction).

However, it still doesn't beat Dustasteride. dutasteride is only in solid form, as far as I know.

Also note, the side effects from topical really aren't any different. In my own personal opinion, I believe
one in twenty (five percent) of men will have side effects. Although nineteen out of twenty (95%), will
not have any issues with it.

It should also be noted, most men who are white, do not regrow temple hair (I said most). However, your
central hairline will probably grow back. And it might/probably will retard temple balding, or completely halt it.

In my opinion, Finasteride should be used with five percent Minoxidil foam. Once your DHT is under control,
a hair regrowth agent helps.


The OP asked about scalp DHT levels. Doesn't fina reduce it by 90% while it reduces systemic DHT by 70%?

If so I would think in theory fina would be a better drug because you still maintain some DHT though out the body whereas duta just kills all DHT by over 90%.
 

Afro_Vacancy

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We know the sensitivity curves for finasteride in the scalp and the serum: its effect saturates at around 0.05 mg/day, which is far lower than the recommended dose.

What are the sensitivity curves in the cerebrospinal fluid, in the liver, and in the prostate?

No idea, but they probably contribute to sides.
 
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